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Gene

SOX4

SRY-box transcription factor 4

Summary

Cytogenetic location
6p22.3
Coordinates
Chromosome 6: 21,593,751–21,598,619 (GRCh38)
Exons
1 exon across 4.9 kb
Protein
474 amino acids
MANE Select transcript
ENST00000244745.4NM_003107.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SOX4 yet. The test sequences your whole genome, so your data includes it all the same.

How SOX4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 6, with a bracket where SOX4 sits. SOX4 and 1 gene near it on chromosome 6, from 21,096,185 to 22,096,184.Chromosome 66p22.3p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2721.2 Mb21.4 Mb21.6 Mb21.8 Mb22 MbCDKAL1: 20,534,442–21,232,855, forward strandCDKAL1SOX4: 21,593,751–21,598,619, forward strandSOX4Diagram of SOX4: one exon on the forward strand of chromosome 6Exon 1: 13 known disease-causing sitesExon 1: 21,593,751–21,598,619, 4,869 bases15′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.9 kb of the gene's 4.9 kb; 1,425 of those bases code for the protein.

How a genome test reads SOX4

13

positions in SOX4 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 4.9 kb of SOX4, introns included, not only the 4.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SOX4 gene: SRY-box transcription factor 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/sox4

Vancouver

Dante Labs. SOX4 gene: SRY-box transcription factor 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sox4

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