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Gene

RALGAPA1

Ral GTPase activating protein catalytic subunit alpha 1

Summary

Cytogenetic location
14q13.2
Coordinates
Chromosome 14: 35,538,356–35,809,295 (GRCh38)
Exons
42 exons across 270.9 kb
Protein
2,542 amino acids
Also known as
GRIPE, DKFZp667F074, KIAA0884, Tulip1, RalGAPalpha1
Previous symbols
GARNL1
MANE Select transcript
ENST00000680220.1NM_001346249.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RALGAPA1 yet. The test sequences your whole genome, so your data includes it all the same.

How RALGAPA1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where RALGAPA1 sits. RALGAPA1 and 6 genes near it on chromosome 14, from 35,173,826 to 36,173,825.Chromosome 1414q13.2p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3335.2 Mb35.4 Mb35.6 Mb35.8 Mb36 MbPRORP: 35,121,842–35,278,538, forward strandPRORP: 35,122,549–35,317,474, forward strandPSMA6: 35,278,596–35,318,734, forward strandPSMA6NFKBIA: 35,401,079–35,404,749, reverse strandNFKBIAINSM2: 35,534,164–35,537,054, forward strandINSM2RALGAPA1: 35,538,356–35,809,295, reverse strandRALGAPA1BRMS1L: 35,826,299–35,932,325, forward strandBRMS1LDiagram of RALGAPA1: 42 exons on the reverse strand of chromosome 14Exon 37: 1 known disease-causing siteExon 28: 1 known disease-causing siteExon 25: 1 known disease-causing siteExon 18: 1 known disease-causing siteExon 11: 1 known disease-causing siteExon 42: 35,538,356–35,539,690, 1,335 basesExon 41: 35,548,508–35,548,538, 31 basesExon 40: 35,549,110–35,549,234, 125 basesExon 39: 35,570,617–35,570,744, 128 basesExon 38: 35,572,560–35,572,718, 159 basesExon 37: 35,595,634–35,595,789, 156 basesExon 36: 35,605,586–35,605,709, 124 basesExon 35: 35,625,361–35,625,432, 72 basesExon 34: 35,627,090–35,627,951, 862 basesExon 33: 35,634,574–35,634,757, 184 basesExon 32: 35,635,464–35,635,598, 135 basesExon 31: 35,651,805–35,651,873, 69 basesExon 30: 35,654,367–35,654,477, 111 basesExon 29: 35,655,807–35,655,915, 109 basesExon 28: 35,659,138–35,659,196, 59 basesExon 27: 35,664,642–35,664,767, 126 basesExon 26: 35,671,389–35,671,517, 129 basesExon 25: 35,672,867–35,673,022, 156 basesExon 24: 35,674,180–35,674,278, 99 basesExon 23: 35,674,516–35,674,709, 194 basesExon 22: 35,677,950–35,678,102, 153 basesExon 21: 35,683,809–35,683,985, 177 basesExon 20: 35,684,929–35,685,145, 217 basesExon 19: 35,686,542–35,686,666, 125 basesExon 18: 35,688,459–35,690,003, 1,545 basesExon 17: 35,700,162–35,700,302, 141 basesExon 16: 35,721,688–35,721,849, 162 basesExon 15: 35,723,027–35,723,264, 238 basesExon 14: 35,725,024–35,725,153, 130 basesExon 13: 35,728,362–35,728,510, 149 basesExon 12: 35,738,513–35,738,650, 138 basesExon 11: 35,742,368–35,742,565, 198 basesExon 10: 35,748,585–35,748,824, 240 basesExon 9: 35,750,482–35,750,690, 209 basesExon 8: 35,752,024–35,752,162, 139 basesExon 7: 35,756,793–35,756,908, 116 basesExon 6: 35,760,829–35,761,006, 178 basesExon 5: 35,762,710–35,762,753, 44 basesExon 4: 35,770,942–35,770,999, 58 basesExon 3: 35,775,006–35,775,055, 50 basesExon 2: 35,775,635–35,775,745, 111 basesExon 1: 35,808,730–35,809,295, 566 bases4240353025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.4 kb of the gene's 270.9 kb; 7,629 of those bases code for the protein.

How a genome test reads RALGAPA1

6

positions in RALGAPA1 where ClinVar classes a change as pathogenic or likely pathogenic

4 of them (67%) fall in regions short reads find hard.

  • Low mappability (4 sites)Regions where 100 bp or 250 bp reads cannot be placed uniquely.

A whole genome covers all 270.9 kb of RALGAPA1, introns included, not only the 9.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RALGAPA1 gene: Ral GTPase activating protein catalytic subunit alpha 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/ralgapa1

Vancouver

Dante Labs. RALGAPA1 gene: Ral GTPase activating protein catalytic subunit alpha 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ralgapa1

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