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Gene

CCDC8

coiled-coil domain containing 8 subunit of 3M complex

Summary

Cytogenetic location
19q13.32
Coordinates
Chromosome 19: 46,410,329–46,413,564 (GRCh38)
Exons
1 exon across 3.2 kb
Protein
538 amino acids
Also known as
DKFZp564K0322, 3M3, PPP1R20, p90
MANE Select transcript
ENST00000307522.5NM_032040.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CCDC8 yet. The test sequences your whole genome, so your data includes it all the same.

How CCDC8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 19, with a bracket where CCDC8 sits. CCDC8 and 23 genes near it on chromosome 19, from 45,911,947 to 46,911,946.Chromosome 1919q13.32p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4346 Mb46.2 Mb46.4 Mb46.6 Mb46.8 MbNANOS2: 45,913,214–45,914,778, reverse strandNANOS2NOVA2: 45,933,734–45,974,044, reverse strandNOVA2CCDC61: 45,995,444–46,021,318, forward strandCCDC61PGLYRP1: 46,019,153–46,023,367, reverse strandPGLYRP1IGFL4: 46,039,182–46,077,118, reverse strandIGFL4IGFL2: 46,079,126–46,161,298, forward strandIGFL2IGFL3: 46,120,067–46,124,698, reverse strandIGFL3IGFL1: 46,229,732–46,231,243, forward strandIGFL1HIF3A: 46,297,026–46,343,433, forward strandHIF3APPP5C: 46,346,994–46,393,000, forward strandPPP5CCCDC8: 46,410,329–46,413,564, reverse strandCCDC8PNMA8C: 46,424,697–46,428,936, reverse strandPNMA8CPNMA8A: 46,466,491–46,471,572, reverse strandPNMA8APNMA8B: 46,486,906–46,495,879, reverse strandPNMA8BCALM3: 46,601,074–46,610,795, forward strandCALM3PTGIR: 46,618,550–46,625,534, reverse strandPTGIRGNG8: 46,633,947–46,639,623, reverse strandGNG8DACT3: 46,646,872–46,661,199, reverse strandDACT3PRKD2: 46,673,661–46,717,144, reverse strandPRKD2STRN4: 46,719,507–46,746,994, reverse strandSTRN4FKRP: 46,746,046–46,776,988, forward strandFKRPSLC1A5: 46,758,394–46,788,617, reverse strandSLC1A5AP2S1: 46,838,136–46,850,962, reverse strandAP2S1ARHGAP35: 46,860,433–47,005,077, forward strandARHGAP35Diagram of CCDC8: one exon on the reverse strand of chromosome 19Exon 1: 13 known disease-causing sitesExon 1: 46,410,329–46,413,564, 3,236 bases15′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.2 kb of the gene's 3.2 kb; 1,617 of those bases code for the protein.

How a genome test reads CCDC8

13

positions in CCDC8 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 3.2 kb of CCDC8, introns included, not only the 3.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CCDC8 gene: coiled-coil domain containing 8 subunit of 3M complex. Retrieved 16 October 2026, from https://dantelabs.com/genes/ccdc8

Vancouver

Dante Labs. CCDC8 gene: coiled-coil domain containing 8 subunit of 3M complex [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ccdc8

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