유전자
STAT4
signal transducer and activator of transcription 4
요약
- 세포유전학적 위치
- 2q32.2-q32.3
- 좌표
- 염색체 2: 191,029,576–191,150,994 (GRCh38)
- 엑손
- 엑손 24개, 121.4 kb에 걸쳐
- 단백질
- 아미노산 748개
- MANE Select 전사체
- ENST00000392320.7NM_003151.4
- 유전자좌 유형
- gene with protein product
- Very high
- Confident
- Low
- Very low
기준 게놈GRCh38hg38
유전자 및 변이 페이지의 위치 정보는 이 브라우저에서 선택한 설정을 따릅니다.
이 유전자와 관련된 큐레이션 보고서
No Genome Test report reads STAT4 yet. The test sequences your whole genome, so your data includes it all the same.
STAT4의 구조
- 코딩 서열
- 비번역 영역
- 인트론
- 전사 방향
- 짧은 리드가 판독하기 어려운 구간
v1.5 릴리스 기준, 이 유전자의 MANE Select 전사체 엑손이며 NCBI와 EMBL-EBI 자료를 바탕으로 하고 GRCh38 참조 게놈에 기반합니다.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
유전자 전체 121.4 kb 중 엑손이 2.6 kb를 차지하며, 이 중 2,247개의 염기가 단백질을 암호화합니다.
Traits linked to STAT4
The Human Phenotype Ontology lists these as features of the rare conditions STAT4 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the immune system
- Antinuclear antibody positivity
- Decreased circulating complement C3 concentration
- Decreased circulating complement C4 concentration
- Meningitis
- Abnormal circulating interleukin concentration
- Acne
- Anti-complement component C1q antibody positivity
- Anti-ribosome Po antibody positivity
Show 26 more traits
- Anti-titin antibody positivity
- Antineutrophil antibody positivity
- Antiphospholipid antibody positivity
- Autoimmunity
- Erythema nodosum
- Immunologic hypersensitivity
- Increased circulating interferon-gamma concentration
- Increased inflammatory response
- Malar rash
- Pimple
- Recurrent infections
- Skin rash
- Anti-dsDNA antibody positivity
- Anti-La/SS-B antibody positivity
- Anti-nucleoporin 62 antibody positivity
- Anti-phosphatidic acid antibody positivity
- Anti-Ro52/TRIM21 antibody positivity
- Anti-Sm antibody positivity
- Anti-U1 ribonucleoprotein antibody positivity
- Brain inflammation
- Discoid lupus rash
- Lupus anticoagulant
- Muscle inflammation
- Non-infectious meningitis
- Serositis
- Systemic lupus erythematosus
Abnormality of the nervous system
- Migraine
- Abnormal gait
- Confusion
- Headache
- Weakness of one side of body
- Abnormal pyramidal sign
- Abnormality of the nervous system
- Ataxia
Show 16 more traits
- Behavioral abnormality
- Cranial nerve paralysis
- Depression
- Disturbances of consciousness
- Epilepsy
- Increased reflexes
- Irritability
- Loss of developmental milestones
- Memory impairment
- Paralysis on one side of body
- Pins and needles feeling
- Psychosis
- Rise in pressure inside skull
- Chorea
- Cognitive impairment
- Language impairment
Abnormality of the genitourinary system
- Inflammation of testicles
- Genital ulcers
- Kidney inflammation
- Lupus nephritis
- Nephrotic syndrome
- Renal failure
- Urinary tract abnormalities
- Epididymitis
Show 2 more traits
Abnormality of the integument
- Morphea
- Open skin sore
- Firm lump under the skin
- Papule
- Abnormal blistering of the skin
- Abnormality of the skin
- Hair loss
- Positive pathergy test
Show 2 more traits
외부 링크
단백질
이 정보의 출처
- HGNC: 유전자의 기호, 명칭, 다른 기호 및 위치입니다.
- NCBI와 EMBL-EBI의 MANE Select v1.5: 전사체, 엑손 및 코딩 서열입니다.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). STAT4 gene: signal transducer and activator of transcription 4. Retrieved 2026년 10월 17일, from https://dantelabs.com/ko/genes/stat4
Dante Labs. STAT4 gene: signal transducer and activator of transcription 4 [Internet]. [cited 2026년 10월 17일]. Available from: https://dantelabs.com/ko/genes/stat4
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