Atlas유전자
ROR2
ROR family WNT receptor 2
요약
- 세포유전학적 위치
- 9q22.31
- 좌표
- 염색체 9: 91,722,601–91,950,228 (GRCh38)
- 엑손
- 엑손 9개, 227.6 kb에 걸쳐
- 단백질
- 아미노산 943개
- 이전 기호
- NTRKR2, BDB, BDB1
- MANE Select 전사체
- ENST00000375708.4NM_004560.4
- 유전자좌 유형
- Protein-coding
- Very high
- Confident
- Low
- Very low
Atlas이 페이지의 데이터
페이지 주소 끝에 .json을 붙이거나 application/json을 요청하면 JSON 형식으로 읽을 수 있습니다.
library(jsonlite)
url <- "https://dantelabs.com/genes/ror2.json"
page <- fromJSON(url)
page$gene$name이 유전자와 관련된 큐레이션 보고서
No Genome Test report reads ROR2 yet. The test sequences your whole genome, so your data includes it all the same.
ROR2의 구조
- 코딩 서열
- 비번역 영역
- 인트론
- 전사 방향
- 알려진 질병 유발 부위
- 짧은 리드가 판독하기 어려운 구간
v1.5 릴리스 기준, 이 유전자의 MANE Select 전사체 엑손이며 NCBI와 EMBL-EBI 자료를 바탕으로 하고 GRCh38 참조 게놈에 기반합니다.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
유전자 전체 227.6 kb 중 엑손이 4.2 kb를 차지하며, 이 중 2,832개의 염기가 단백질을 암호화합니다.
전장 유전체 검사가 ROR2 유전자를 읽는 방법
25
ROR2 내 위치 중 ClinVar가 병원성 또는 가능성 높은 병원성으로 분류하는 위치
이 중 어느 곳도 짧은 리드가 판독하기 어려운 구간에 있지 않습니다.
전장 유전체 검사는 인트론을 포함해 ROR2의 전체 227.6kb를 모두 포함하며, 엑손 4.2kb만 보는 것이 아닙니다.
Traits linked to ROR2
The Human Phenotype Ontology lists these as features of the rare conditions ROR2 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Short nose
- Abnormal dentition
- Downturned corners of mouth
- Midface retrusion
- Nasal tip, upturned
- Open bite
- Prominent forehead
- Wide mouth
Show 36 more traits
- Wide nasal bridge
- Abnormally small tongue
- Big calvaria
- Broad opening between the eyelids
- Cleft tongue
- Decreased number of teeth
- Depressed nasal bridge
- Downward slanting of the opening between the eyelids
- Eye folds
- Frontal bossing
- Gum enlargement
- Little lower jaw
- Long eyelashes
- Long philtrum
- Narrow palate
- Receding chin
- Short neck
- Tented mouth
- Thin red part of the upper lip
- Tongue tied
- Triangular mouth
- Upward slanting of the opening between the eyelids
- Abnormality of the palate
- Cleft of the mouth
- Exaggerated cupid's bow
- Extra teeth
- Failure of development of between one and six teeth
- Short philtrum
- Abnormally large tongue
- Absent uvula
- Delayed cranial suture closure
- Delayed eruption of permanent teeth
- Dental crowding
- Flat face
- Wider-than-typical soft spot of skull
- Zygomatic flattening
Abnormality of limbs
- Disproportionately short middle portion of limb
- Fused innermost and middle bones of little finger
- Short fingers or toes
- Absent/small outermost finger bone of the hand
- Curvature of digit
- Curvature of little finger
- Short outermost finger bone
- Short palm
Show 34 more traits
- Bilateral ulnar hypoplasia
- Bowing of outer large bone of the forearm
- Broad big toe
- Broad bone of big toe
- Broad thumb
- Dislocated radial head
- Elbow dislocation
- Limited pronation/supination of forearm
- Mesomelic arm shortening
- Single interphalangeal crease of fifth finger
- Underdeveloped outer large forearm bone
- Bilateral single transverse palmar creases
- Finger syndactyly
- Fused toes
- Fusion of wrist bones
- Gap between 1st and 2nd toes
- Hip dislocation
- Permanent flexion of the finger
- Single transverse palmar crease
- Split hand
- Webbed fingers
- Webbed fingers or toes
- Absent/small long bones of hand
- Absent/small outermost bones of toe
- Broad toe
- Duplication of the outermost bone of hand
- Joint contracture of the hand
- Notched outermost bones of toes
- Radial deviation of finger
- Short digit
- Short middle bone of finger
- Short middle bone of the little finger
- Small hand
- Type B brachydactyly
Abnormality of the genitourinary system
- Short penis
- Underdeveloped penis
- Hydronephrosis
- Increased calcium level in kidney
- Kidney stone
- Underdeveloped female external genitalia
- Underdeveloped inner lips
- Undescended testes
Show 4 more traits
Abnormality of the integument
- Small nail
- Abnormal fingernail development
- Atypical nail growth
- Beauty mark
- Hair loss
- port-wine stain
- Spinal dimple
- Absent nails
Show 1 more traits
Abnormality of the cardiovascular system
- Abnormal aortic morphology
- Abnormal pulmonary valve morphology
- Abnormal tricuspid valve morphology
- Abnormality of the heart
- An opening in the wall separating the top two chambers of the heart
- Hole in heart wall separating two lower heart chambers
- Tetralogy of Fallot
- Right ventricular outlet tract obstruction
외부 링크
단백질
이 정보의 출처
- HGNC: 유전자의 기호, 명칭, 다른 기호 및 위치입니다.
- NCBI와 EMBL-EBI의 MANE Select v1.5: 전사체, 엑손 및 코딩 서열입니다.
- ClinVar와 GIAB 층화 자료: 알려진 질병 유발 부위와 짧은 리드(short read)로 분석하기 어려운 영역입니다.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- 데이터 릴리스 2026.10.17-8666dff2.
Cite this page
Dante Labs. (n.d.). ROR2 gene: ROR family WNT receptor 2. Retrieved 2026년 10월 18일, from https://dantelabs.com/ko/genes/ror2
Dante Labs. ROR2 gene: ROR family WNT receptor 2 [Internet]. [cited 2026년 10월 18일]. Available from: https://dantelabs.com/ko/genes/ror2
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