AtlasPožymis
Brittle nails
Klinikinis pavadinimas: Fragile nails
Nails that easily break.
Santrauka
- Kūno sistema
- Abnormality of the integument
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Ši puslapis kaip duomenys
Norėdami perskaityti jį kaip JSON, pridėkite .json prie puslapio adreso arba nurodykite application/json.
library(jsonlite)
url <- "https://dantelabs.com/traits/fragile-nails.json"
page <- fromJSON(url)
page$trait$nameVienu tyrimu sužinokite genus, susijusius su Brittle nails, ir kitą jūsų genomo dalį.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test30 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Epidermolysis BullosaReads 5 of these genesCOL7A1KRT14DSPCOL17A1LAMB3About this report →
- Craniofrontonasal SyndromeReads 1 of these genesEFNB1About this report →
- Hereditary Palmoplantar Keratodermas and Pachyonychia CongenitaReads 5 of these genesKRT14DSPAP1B1GJA1SLURP1About this report →
- Darier and Hailey-Hailey DiseaseReads 1 of these genesATP2A2About this report →
Show 26 more reports
- Amelogenesis ImperfectaReads 2 of these genesDLX3LAMB3About this report →
- DNA Repair DiseaseReads 3 of these genesERCC2ERCC3GTF2H5About this report →
- Hereditary Orofacial CleftingReads 1 of these genesMSX1About this report →
- Hypodontia and AnodontiaReads 1 of these genesMSX1About this report →
- Progressive Cardiac Conduction Disease & Sick Sinus SyndromeReads 1 of these genesLMNAAbout this report →
- Charcot-Marie-Tooth DiseaseReads 3 of these genesITPR3LMNAAARS1About this report →
- Neurodegeneration with Brain Iron Accumulation (NBIA)Reads 1 of these genesFTLAbout this report →
- Arrhythmogenic CardiomyopathyReads 1 of these genesDSPAbout this report →
- LipodystrophyReads 1 of these genesLMNAAbout this report →
- Cutis LaxaReads 1 of these genesATP6V0A2About this report →
- Ectodermal DysplasiasReads 1 of these genesKRT14About this report →
- Hereditary Corneal DystrophiesReads 1 of these genesCOL17A1About this report →
- Noonan SyndromeReads 1 of these genesHRASAbout this report →
- Hereditary Congenital & Juvenile CataractReads 1 of these genesFTLAbout this report →
- Rare Hereditary Peripheral NeuropathiesReads 3 of these genesITPR3LMNAAARS1About this report →
- Intellectual DisabilityReads 3 of these genesFOSL2SIN3ACAMK2GAbout this report →
- Microphthalmia, Anophthalmia & ColobomaReads 1 of these genesERCC2About this report →
- Limb-Girdle Muscular DystrophyReads 1 of these genesLMNAAbout this report →
- Osteogenesis ImperfectaReads 1 of these genesATP6V0A2About this report →
- Dilated CardiomyopathyReads 1 of these genesLMNAAbout this report →
- Hypertrophic CardiomyopathyReads 1 of these genesHRASAbout this report →
- Other Inherited LeukodystrophiesReads 1 of these genesAARS1About this report →
- Inherited Neurodegenerative DisordersReads 2 of these genesAARS1FTLAbout this report →
- Congenital Disorders of GlycosylationReads 1 of these genesATP6V0A2About this report →
- Epilepsy (Full Panel)Reads 1 of these genesAARS1About this report →
- Other Inborn Errors of ImmunityReads 1 of these genesITPR3About this report →
Vienu tyrimu sužinokite genus, susijusius su Brittle nails, ir kitą jūsų genomo dalį.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test35 genų susiję su Brittle nails
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Brittle nails. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| HEPHL1hephaestin like 1 | Visada | 1 ligoje |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Visada | 1 ligoje |
| COL7A1collagen type VII alpha 1 chain | Labai dažnai (80–99%) | 1 ligoje |
| LMNAlamin A/C | Labai dažnai (80–99%) | 1 ligoje |
| MSX1msh homeobox 1 | Labai dažnai (80–99%) | 1 ligoje |
| ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 | Dažnai (30–79%) | 1 ligoje |
| DLX3distal-less homeobox 3 | Dažnai (30–79%) | 2 ligose |
| KRT14keratin 14 | Dažnai (30–79%) | 2 ligose |
| PRKD1protein kinase D1 | Dažnai (30–79%) | 1 ligoje |
| SMARCD2SWI/SNF related BAF chromatin remodeling complex subunit D2 | Dažnai (30–79%) | 1 ligoje |
| TRPS1transcriptional repressor GATA binding 1 | Dažnai (30–79%) | 1 ligoje |
| AARS1alanyl-tRNA synthetase 1 | Kartais (5–29%) | 1 ligoje |
| CARS1cysteinyl-tRNA synthetase 1 | Kartais (5–29%) | 1 ligoje |
| DBR1debranching RNA lariats 1 | Kartais (5–29%) | 1 ligoje |
| DSPdesmoplakin | Kartais (5–29%) | 1 ligoje |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Kartais (5–29%) | 2 ligose |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Kartais (5–29%) | 1 ligoje |
| FOSL2FOS like 2, AP-1 transcription factor subunit | Kartais (5–29%) | 1 ligoje |
| FTLferritin light chain | Kartais (5–29%) | 1 ligoje |
| GTF2E2general transcription factor IIE subunit 2 | Kartais (5–29%) | 1 ligoje |
| GTF2H5general transcription factor IIH subunit 5 | Kartais (5–29%) | 1 ligoje |
| MPLKIPM-phase specific PLK1 interacting protein | Kartais (5–29%) | 1 ligoje |
| RNF113Aring finger protein 113A | Kartais (5–29%) | 1 ligoje |
| SIN3ASIN3 transcription regulator family member A | Kartais (5–29%) | 2 ligose |
| SIN3BSIN3 transcription regulator family member B | Kartais (5–29%) | 1 ligoje |
| TARS1threonyl-tRNA synthetase 1 | Kartais (5–29%) | 1 ligoje |
| CAMK2Gcalcium/calmodulin dependent protein kinase II gamma | Retai (1–4 %) | 1 ligoje |
| AP1B1adaptor related protein complex 1 subunit beta 1 | Neužfiksuota | 1 ligoje |
| ATP6V0A2ATPase H+ transporting V0 subunit a2 | Neužfiksuota | 1 ligoje |
| COL17A1collagen type XVII alpha 1 chain | Neužfiksuota | 1 ligoje |
| EFNB1ephrin B1 | Neužfiksuota | 1 ligoje |
| GJA1gap junction protein alpha 1 | Neužfiksuota | 1 ligoje |
| HRASHRas proto-oncogene, GTPase | Neužfiksuota | 1 ligoje |
| LAMB3laminin subunit beta 3 | Neužfiksuota | 1 ligoje |
| SLURP1secreted LY6/PLAUR domain containing 1 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.19-9814e911.
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