Trait
Gray matter heterotopia
Heterotopia or neuronal heterotopia are macroscopic clusters of misplaced neurons (gray matter), most often situated along the ventricular walls or within the subcortical white matter.
Summary
- Also called
- Gray matter heterotopias, Grey matter heterotopia, Grey matter heterotopias, Heterotopia, Heterotopias, Neuronal heterotopia
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Gray matter heterotopia, and the rest of your genome, with one test.
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Get my Genome Test97 genes linked to Gray matter heterotopia
Changes in these genes cause rare conditions in which Gray matter heterotopia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ACTBactin beta | Always | In 1 condition |
| B4GAT1beta-1,4-glucuronyltransferase 1 | Always | In 1 condition |
| EML1EMAP like 1 | Always | In 1 condition |
| GPSM2G protein signaling modulator 2 | Always | In 2 conditions |
| MAP1Bmicrotubule associated protein 1B | Always | In 1 condition |
| NEDD4LNEDD4 like E3 ubiquitin protein ligase | Always | In 1 condition |
| PEX14peroxisomal biogenesis factor 14 | Always | In 1 condition |
| RAP1BRAP1B, member of RAS oncogene family | Always | In 1 condition |
| RNU4-2RNA, U4 small nuclear 2 | Always | In 1 condition |
| WSB2WD repeat and SOCS box containing 2 | Always | In 1 condition |
| ANKLE2ankyrin repeat and LEM domain containing 2 | Very often (80–99%) | In 1 condition |
| ASPMassembly factor for spindle microtubules | Very often (80–99%) | In 1 condition |
| CDK5RAP2CDK5 regulatory subunit associated protein 2 | Very often (80–99%) | In 1 condition |
| CDK6cyclin dependent kinase 6 | Very often (80–99%) | In 1 condition |
| CENPEcentromere protein E | Very often (80–99%) | In 1 condition |
| CEP135centrosomal protein 135 | Very often (80–99%) | In 1 condition |
| CEP152centrosomal protein 152 | Very often (80–99%) | In 1 condition |
| CITcitron rho-interacting serine/threonine kinase | Very often (80–99%) | In 1 condition |
| COPB2coat protein complex I subunit beta 2 | Very often (80–99%) | In 1 condition |
| CPAPcentrosome assembly and centriole elongation protein | Very often (80–99%) | In 1 condition |
| ERMARDER membrane associated RNA degradation | Very often (80–99%) | In 1 condition |
| KIF14kinesin family member 14 | Very often (80–99%) | In 1 condition |
| KNL1kinetochore scaffold 1 | Very often (80–99%) | In 1 condition |
| MCM7minichromosome maintenance complex component 7 | Very often (80–99%) | In 1 condition |
| MCPH1microcephalin 1 | Very often (80–99%) | In 1 condition |
| METTL5methyltransferase 5, N6-adenosine | Very often (80–99%) | In 1 condition |
| MFSD2AMFSD2 lysolipid transporter A, lysophospholipid | Very often (80–99%) | In 1 condition |
| NCAPD3non-SMC condensin II complex subunit D3 | Very often (80–99%) | In 1 condition |
| NUP37nucleoporin 37 | Very often (80–99%) | In 1 condition |
| PDCD6IPprogrammed cell death 6 interacting protein | Very often (80–99%) | In 1 condition |
| PHC1polyhomeotic homolog 1 | Very often (80–99%) | In 1 condition |
| PYCR2pyrroline-5-carboxylate reductase 2 | Very often (80–99%) | In 1 condition |
| SARS1seryl-tRNA synthetase 1 | Very often (80–99%) | In 1 condition |
| SASS6SAS-6 centriolar assembly protein | Very often (80–99%) | In 1 condition |
| STILSTIL centriolar assembly protein | Very often (80–99%) | In 1 condition |
| TAF13TATA-box binding protein associated factor 13 | Very often (80–99%) | In 1 condition |
| TRAPPC10trafficking protein particle complex subunit 10 | Very often (80–99%) | In 1 condition |
| TRAPPC14trafficking protein particle complex subunit 14 | Very often (80–99%) | In 1 condition |
| WARS1tryptophanyl-tRNA synthetase 1 | Very often (80–99%) | In 1 condition |
| WDR62WD repeat domain 62 | Very often (80–99%) | In 2 conditions |
Show 57 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| EPG5ectopic P-granules 5 autophagy tethering factor | Often (30–79%) | In 2 conditions |
| FKRPfukutin related protein | Often (30–79%) | In 2 conditions |
| GGT1gamma-glutamyltransferase 1 | Often (30–79%) | In 1 condition |
| GMPPBGDP-mannose pyrophosphorylase B | Often (30–79%) | In 1 condition |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Often (30–79%) | In 2 conditions |
| LAMB1laminin subunit beta 1 | Often (30–79%) | In 2 conditions |
| MAN2C1mannosidase alpha class 2C member 1 | Often (30–79%) | In 1 condition |
| MLH1mutL homolog 1 | Often (30–79%) | In 1 condition |
| PMS2PMS1 homolog 2, mismatch repair system component | Often (30–79%) | In 1 condition |
| POMGNT1protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | Often (30–79%) | In 1 condition |
| POMKprotein O-mannose kinase | Often (30–79%) | In 1 condition |
| POMT1protein O-mannosyltransferase 1 | Often (30–79%) | In 2 conditions |
| POMT2protein O-mannosyltransferase 2 | Often (30–79%) | In 1 condition |
| SLC4A10solute carrier family 4 member 10 | Often (30–79%) | In 1 condition |
| TCP1t-complex 1 | Often (30–79%) | In 1 condition |
| TMTC3transmembrane O-mannosyltransferase targeting cadherins 3 | Often (30–79%) | In 1 condition |
| UGGT1UDP-glucose glycoprotein glucosyltransferase 1 | Often (30–79%) | In 1 condition |
| ADD3adducin 3 | Sometimes (5–29%) | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Sometimes (5–29%) | In 1 condition |
| AKT3AKT serine/threonine kinase 3 | Sometimes (5–29%) | In 1 condition |
| ALG11ALG11 alpha-1,2-mannosyltransferase | Sometimes (5–29%) | In 1 condition |
| ARMC9armadillo repeat containing 9 | Sometimes (5–29%) | In 1 condition |
| CRB2crumbs cell polarity complex component 2 | Sometimes (5–29%) | In 1 condition |
| DCHS1dachsous cadherin-related 1 | Sometimes (5–29%) | In 2 conditions |
| FAT4FAT atypical cadherin 4 | Sometimes (5–29%) | In 2 conditions |
| FGFR3fibroblast growth factor receptor 3 | Sometimes (5–29%) | In 2 conditions |
| LMBRD2LMBR1 domain containing 2 | Sometimes (5–29%) | In 1 condition |
| MTORmechanistic target of rapamycin kinase | Sometimes (5–29%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| PLCH1phospholipase C eta 1 | Sometimes (5–29%) | In 1 condition |
| PPFIBP1PPFIB scaffold protein 1 | Sometimes (5–29%) | In 1 condition |
| PPP1R12Aprotein phosphatase 1 regulatory subunit 12A | Sometimes (5–29%) | In 1 condition |
| RALGAPA1Ral GTPase activating protein catalytic subunit alpha 1 | Sometimes (5–29%) | In 1 condition |
| RNU2-2RNA, U2 small nuclear 2 | Sometimes (5–29%) | In 1 condition |
| RNU4ATACRNA, U4atac small nuclear | Sometimes (5–29%) | In 1 condition |
| SPENspen family transcriptional repressor | Sometimes (5–29%) | In 1 condition |
| TUBB2Btubulin beta 2B class IIb | Sometimes (5–29%) | In 1 condition |
| CRPPACDP-L-ribitol pyrophosphorylase A | Rarely (1–4%) | In 2 conditions |
| FKTNfukutin | Rarely (1–4%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Not recorded | In 1 condition |
| BLTP1bridge-like lipid transfer protein family member 1 | Not recorded | In 1 condition |
| DCXdoublecortin | Not recorded | In 1 condition |
| FLNAfilamin A | Not recorded | In 1 condition |
| HYLS1HYLS1 centriolar and ciliogenesis associated | Not recorded | In 1 condition |
| KANSL1KAT8 regulatory NSL complex subunit 1 | Not recorded | In 1 condition |
| KIF2Akinesin family member 2A | Not recorded | In 1 condition |
| LAMA1laminin subunit alpha 1 | Not recorded | In 1 condition |
| MED12mediator complex subunit 12 | Not recorded | In 1 condition |
| MPDZmultiple PDZ domain crumbs cell polarity complex component | Not recorded | In 1 condition |
| OFD1OFD1 centriole and centriolar satellite protein | Not recorded | In 1 condition |
| PAFAH1B1platelet activating factor acetylhydrolase 1b regulatory subunit 1 | Not recorded | In 1 condition |
| PEX1peroxisomal biogenesis factor 1 | Not recorded | In 1 condition |
| SLC25A24solute carrier family 25 member 24 | Not recorded | In 1 condition |
| TMEM107transmembrane protein 107 | Not recorded | In 1 condition |
| TUBA1Atubulin alpha 1a | Not recorded | In 1 condition |
| USP18ubiquitin specific peptidase 18 | Not recorded | In 1 condition |
| ZSWIM6zinc finger SWIM-type containing 6 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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