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Gene

MCM7

minichromosome maintenance complex component 7

Summary

Cytogenetic location
7q22.1
Coordinates
Chromosome 7: 100,092,728–100,101,397 (GRCh38)
Exons
15 exons across 8.7 kb
Protein
719 amino acids
Also known as
CDC47, PPP1R104
Previous symbols
MCM2
MANE Select transcript
ENST00000303887.10NM_005916.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MCM7 yet. The test sequences your whole genome, so your data includes it all the same.

How MCM7 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where MCM7 sits. MCM7 and 42 genes near it on chromosome 7, from 99,597,063 to 100,597,062.Chromosome 77q22.1p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.399.6 Mb99.8 Mb100 Mb100.2 Mb100.4 Mb: 99,558,695–99,607,810, forward strandTMEM225B: 99,597,868–99,611,045, forward strandTMEM225BZSCAN25: 99,616,623–99,738,531, forward strandZSCAN25CYP3A5: 99,647,442–99,680,043, reverse strandCYP3A5CYP3A7-CYP3A51P: 99,684,957–99,735,102, reverse strandCYP3A7-CYP3A51PCYP3A7: 99,704,105–99,735,196, reverse strandCYP3A7CYP3A4: 99,756,954–99,784,327, reverse strandCYP3A4CYP3A43: 99,827,922–99,867,801, forward strandCYP3A43OR2AE1: 99,876,062–99,877,033, reverse strandOR2AE1TRIM4: 99,876,958–99,919,604, reverse strandTRIM4GJC3: 99,923,266–99,929,620, reverse strandGJC3AZGP1: 99,966,720–99,976,074, reverse strandAZGP1ZKSCAN1: 100,015,570–100,047,430, forward strandZKSCAN1ZSCAN21: 100,049,767–100,081,304, forward strandZNF3: 100,056,868–100,082,706, reverse strandZNF3COPS6: 100,088,948–100,095,185, forward strandCOPS6MCM7: 100,092,728–100,101,397, reverse strandMCM7AP4M1: 100,100,841–100,110,345, forward strandAP4M1TAF6: 100,106,876–100,127,187, reverse strandTAF6CNPY4: 100,119,614–100,125,511, forward strandMBLAC1: 100,126,694–100,128,498, forward strandLAMTOR4: 100,148,888–100,155,945, forward strandTRAPPC14: 100,154,420–100,158,737, reverse strandGAL3ST4: 100,159,244–100,168,953, reverse strandGPC2: 100,169,602–100,177,389, reverse strandGPC2STAG3: 100,177,563–100,214,387, forward strandSTAG3: 100,205,357–100,221,488, forward strandPVRIG: 100,218,241–100,221,490, forward strandPVRIGSPDYE3: 100,307,702–100,322,372, forward strandSPDYE3PILRB: 100,351,627–100,367,831, forward strandPILRBPILRA: 100,367,530–100,400,098, forward strandPILRA: 100,397,577–100,434,107, forward strandZCWPW1: 100,400,826–100,428,992, reverse strandZCWPW1MEPCE: 100,428,322–100,435,138, forward strandMEPCEPPP1R35: 100,435,261–100,436,546, reverse strandSPACDR: 100,456,620–100,464,277, reverse strandTSC22D4: 100,466,508–100,479,257, reverse strand: 100,478,099–100,478,170, reverse strandNYAP1: 100,483,605–100,494,802, forward strandNYAP1AGFG2: 100,539,169–100,569,429, forward strandAGFG2SAP25: 100,572,228–100,573,916, reverse strandSAP25LRCH4: 100,574,011–100,586,236, reverse strandLRCH4FBXO24: 100,583,982–100,601,117, forward strandFBXO24Diagram of MCM7: 15 exons on the reverse strand of chromosome 7Exon 7: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 15: 100,092,728–100,093,133, 406 basesExon 14: 100,093,292–100,093,401, 110 basesExon 13: 100,094,173–100,094,341, 169 basesExon 12: 100,095,387–100,095,470, 84 basesExon 11: 100,095,774–100,096,167, 394 basesExon 10: 100,097,301–100,097,384, 84 basesExon 9: 100,097,614–100,097,745, 132 basesExon 8: 100,097,834–100,097,948, 115 basesExon 7: 100,098,141–100,098,290, 150 basesExon 6: 100,098,578–100,098,715, 138 basesExon 5: 100,099,023–100,099,203, 181 basesExon 4: 100,099,279–100,099,403, 125 basesExon 3: 100,099,589–100,099,753, 165 basesExon 2: 100,100,014–100,100,093, 80 basesExon 1: 100,101,264–100,101,397, 134 bases1514131211109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 8.7 kb; 2,160 of those bases code for the protein.

How a genome test reads MCM7

2

positions in MCM7 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 8.7 kb of MCM7, introns included, not only the 2.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). MCM7 gene: minichromosome maintenance complex component 7. Retrieved 16 October 2026, from https://dantelabs.com/genes/mcm7

Vancouver

Dante Labs. MCM7 gene: minichromosome maintenance complex component 7 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/mcm7

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