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Gene

LAMA1

laminin subunit alpha 1

Summary

Cytogenetic location
18p11.31
Coordinates
Chromosome 18: 6,941,742–7,117,797 (GRCh38)
Exons
63 exons across 176.1 kb
Protein
3,075 amino acids
Previous symbols
LAMA
MANE Select transcript
ENST00000389658.4NM_005559.4
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads LAMA1 yet. The test sequences your whole genome, so your data includes it all the same.

How LAMA1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 18, with a bracket where LAMA1 sits. LAMA1 and 2 genes near it on chromosome 18, from 6,529,770 to 7,529,769.Chromosome 1818p11.31p11.32p11.31p11.23p11.22p11.21p11.1q11.1q11.2q12.1q12.2q12.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q236.6 Mb6.8 Mb7 Mb7.2 Mb7.4 MbARHGAP28: 6,729,668–6,915,716, forward strandARHGAP28LAMA1: 6,941,742–7,117,797, reverse strandLAMA1LRRC30: 7,231,089–7,232,044, forward strandLRRC30Diagram of LAMA1: 63 exons on the reverse strand of chromosome 18Exon 63: 1 known disease-causing siteExon 61: 2 known disease-causing sitesExon 60: 3 known disease-causing sitesExon 58: 1 known disease-causing siteExon 56: 1 known disease-causing siteExon 54: 1 known disease-causing siteExon 50: 1 known disease-causing siteExon 49: 1 known disease-causing siteExon 47: 2 known disease-causing sitesExon 44: 1 known disease-causing siteExon 40: 1 known disease-causing siteExon 39: 1 known disease-causing siteExon 38: 3 known disease-causing sitesExon 37: 1 known disease-causing siteExon 36: 1 known disease-causing siteExon 35: 1 known disease-causing siteExon 33: 3 known disease-causing sitesExon 32: 1 known disease-causing siteExon 29: 2 known disease-causing sitesExon 28: 1 known disease-causing siteExon 27: 1 known disease-causing siteExon 26: 2 known disease-causing sitesExon 24: 2 known disease-causing sitesExon 23: 2 known disease-causing sitesExon 22: 1 known disease-causing siteExon 21: 4 known disease-causing sitesExon 18: 1 known disease-causing siteExon 17: 1 known disease-causing siteExon 14: 1 known disease-causing siteExon 12: 2 known disease-causing sitesExon 10: 1 known disease-causing siteExon 9: 2 known disease-causing sitesExon 8: 1 known disease-causing siteExon 7: 2 known disease-causing sitesExon 5: 1 known disease-causing siteExon 4: 2 known disease-causing sitesExon 3: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 63: 6,941,742–6,942,239, 498 basesExon 62: 6,943,180–6,943,402, 223 basesExon 61: 6,947,163–6,947,296, 134 basesExon 60: 6,948,403–6,948,556, 154 basesExon 59: 6,949,101–6,949,259, 159 basesExon 58: 6,950,782–6,950,971, 190 basesExon 57: 6,955,353–6,955,465, 113 basesExon 56: 6,956,636–6,956,765, 130 basesExon 55: 6,958,477–6,958,662, 186 basesExon 54: 6,959,341–6,959,492, 152 basesExon 53: 6,961,586–6,961,759, 174 basesExon 52: 6,961,945–6,962,059, 115 basesExon 51: 6,964,662–6,964,803, 142 basesExon 50: 6,965,288–6,965,432, 145 basesExon 49: 6,966,147–6,966,297, 151 basesExon 48: 6,971,857–6,971,981, 125 basesExon 47: 6,973,057–6,973,207, 151 basesExon 46: 6,974,903–6,975,036, 134 basesExon 45: 6,975,937–6,976,080, 144 basesExon 44: 6,977,727–6,977,881, 155 basesExon 43: 6,978,196–6,978,378, 183 basesExon 42: 6,980,521–6,980,637, 117 basesExon 41: 6,982,497–6,982,590, 94 basesExon 40: 6,983,099–6,983,234, 136 basesExon 39: 6,985,237–6,985,400, 164 basesExon 38: 6,985,527–6,985,643, 117 basesExon 37: 6,986,137–6,986,347, 211 basesExon 36: 6,992,561–6,992,720, 160 basesExon 35: 6,993,641–6,993,752, 112 basesExon 34: 6,995,357–6,995,446, 90 basesExon 33: 6,997,742–6,997,884, 143 basesExon 32: 6,999,445–6,999,638, 194 basesExon 31: 6,999,911–6,999,997, 87 basesExon 30: 7,002,264–7,002,385, 122 basesExon 29: 7,007,139–7,007,276, 138 basesExon 28: 7,008,488–7,008,608, 121 basesExon 27: 7,009,239–7,009,366, 128 basesExon 26: 7,010,200–7,010,385, 186 basesExon 25: 7,011,300–7,011,479, 180 basesExon 24: 7,011,995–7,012,138, 144 basesExon 23: 7,013,815–7,014,051, 237 basesExon 22: 7,015,722–7,015,858, 137 basesExon 21: 7,016,491–7,016,671, 181 basesExon 20: 7,017,278–7,017,384, 107 basesExon 19: 7,023,164–7,023,375, 212 basesExon 18: 7,024,380–7,024,466, 87 basesExon 17: 7,025,979–7,026,106, 128 basesExon 16: 7,032,066–7,032,176, 111 basesExon 15: 7,032,984–7,033,095, 112 basesExon 14: 7,034,479–7,034,690, 212 basesExon 13: 7,035,987–7,036,088, 102 basesExon 12: 7,037,578–7,037,751, 174 basesExon 11: 7,038,810–7,038,950, 141 basesExon 10: 7,040,076–7,040,236, 161 basesExon 9: 7,042,145–7,042,250, 106 basesExon 8: 7,043,227–7,043,405, 179 basesExon 7: 7,044,722–7,044,839, 118 basesExon 6: 7,046,278–7,046,367, 90 basesExon 5: 7,049,078–7,049,257, 180 basesExon 4: 7,050,694–7,050,936, 243 basesExon 3: 7,079,975–7,080,087, 113 basesExon 2: 7,080,287–7,080,457, 171 basesExon 1: 7,117,660–7,117,797, 138 bases636055504540353025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.6 kb of the gene's 176.1 kb; 9,228 of those bases code for the protein.

How a genome test reads LAMA1

71

positions in LAMA1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 176.1 kb of LAMA1, introns included, not only the 9.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). LAMA1 gene: laminin subunit alpha 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/lama1

Vancouver

Dante Labs. LAMA1 gene: laminin subunit alpha 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/lama1

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