Skip to content
Use your HSA or FSA funds

Gene

B4GAT1

beta-1,4-glucuronyltransferase 1

Summary

Cytogenetic location
11q13.2
Coordinates
Chromosome 11: 66,345,374–66,347,629 (GRCh38)
Exons
2 exons across 2.3 kb
Protein
415 amino acids
Also known as
IGnT, iGAT, BETA3GNTI, B3GN-T1
Previous symbols
B3GNT6, B3GNT1
MANE Select transcript
ENST00000311181.5NM_006876.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Congenital Muscular Dystrophies

    • Congenital muscular dystrophy

      A group of muscular dystrophies with onset at birth or in infancy, including dystroglycanopathies (such as FKRP, FKTN and POMT1/2-related forms).

      • ClinGen rates the link moderate
      • 2 GenCC submitters rate it definitive or strong

How B4GAT1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 11, with a bracket where B4GAT1 sits. B4GAT1 and 46 genes near it on chromosome 11, from 65,846,502 to 66,846,501.Chromosome 1111q13.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2566 Mb66.2 Mb66.4 Mb66.6 Mb66.8 MbCFL1: 65,823,022–65,862,026, reverse strandSNX32: 65,833,664–65,856,896, forward strandMUS81: 65,857,126–65,867,653, forward strandEFEMP2: 65,866,300–65,878,497, reverse strandCTSW: 65,879,809–65,883,741, forward strandFIBP: 65,883,740–65,888,532, reverse strandCCDC85B: 65,890,673–65,891,635, forward strandCCDC85BFOSL1: 65,892,049–65,900,573, reverse strandFOSL1C11orf68: 65,916,810–65,919,137, reverse strandC11orf68DRAP1: 65,919,258–65,921,565, forward strandDRAP1TSGA10IP: 65,945,480–65,960,217, forward strandSART1: 65,961,681–65,980,137, forward strandEIF1AD: 65,992,009–66,002,472, reverse strandBANF1: 66,001,832–66,004,170, forward strandBANF1CST6: 66,011,506–66,013,505, forward strandCST6CATSPER1: 66,016,752–66,026,479, reverse strandCATSPER1GAL3ST3: 66,040,748–66,049,502, reverse strandGAL3ST3SF3B2: 66,050,729–66,069,308, forward strandSF3B2PACS1: 66,070,017–66,248,638, forward strandPACS1KLC2: 66,257,267–66,267,862, forward strandKLC2RAB1B: 66,268,586–66,277,492, forward strandRAB1BCNIH2: 66,278,170–66,285,301, forward strandCNIH2YIF1A: 66,284,253–66,289,688, reverse strandYIF1ATMEM151A: 66,291,832–66,299,036, forward strandCD248: 66,314,494–66,317,044, reverse strandRIN1: 66,330,241–66,336,840, reverse strandRIN1BRMS1: 66,337,332–66,345,136, reverse strandBRMS1B4GAT1: 66,345,374–66,347,629, reverse strandB4GAT1SLC29A2: 66,360,101–66,372,476, reverse strandSLC29A2NPAS4: 66,421,033–66,426,707, forward strandNPAS4MRPL11: 66,435,075–66,466,738, reverse strandMRPL11PELI3: 66,466,303–66,478,998, forward strandPELI3DPP3: 66,479,990–66,510,188, forward strandDPP3: 66,509,079–66,533,613, forward strandBBS1: 66,510,606–66,534,660, forward strandBBS1ZDHHC24: 66,520,620–66,546,244, reverse strandZDHHC24ACTN3: 66,546,395–66,563,334, forward strandACTN3CTSF: 66,563,462–66,568,879, reverse strandCTSFCCDC87: 66,590,176–66,593,063, reverse strandCCDC87CCS: 66,592,843–66,606,703, forward strandCCSRBM14: 66,616,594–66,629,934, forward strandRBM14RBM14-RBM4: 66,616,626–66,646,469, forward strandRBM14-RBM4RBM4: 66,637,771–66,668,380, forward strandRBM4RBM4B: 66,664,994–66,677,925, reverse strandRBM4BSPTBN2: 66,682,496–66,744,670, reverse strandSPTBN2TOP6BL: 66,744,451–66,843,516, forward strandTOP6BLRCE1: 66,842,835–66,848,159, forward strandRCE1Diagram of B4GAT1: 2 exons on the reverse strand of chromosome 11Exon 1: 2 known disease-causing sitesExon 2: 66,345,374–66,346,240, 867 basesExon 1: 66,346,490–66,347,629, 1,140 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 2.3 kb; 1,248 of those bases code for the protein.

How a genome test reads B4GAT1

2

positions in B4GAT1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 2.3 kb of B4GAT1, introns included, not only the 2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). B4GAT1 gene: beta-1,4-glucuronyltransferase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/b4gat1

Vancouver

Dante Labs. B4GAT1 gene: beta-1,4-glucuronyltransferase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/b4gat1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test