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Gene

DCX

doublecortin

Summary

Cytogenetic location
Xq23
Coordinates
Chromosome X: 111,293,779–111,412,192 (GRCh38)
Exons
7 exons across 118.4 kb
Protein
366 amino acids
Also known as
SCLH, DC, LISX, DBCN, XLIS
MANE Select transcript
ENST00000636035.2NM_001195553.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DCX yet. The test sequences your whole genome, so your data includes it all the same.

How DCX is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome X, with a bracket where DCX sits. DCX and 5 genes near it on chromosome X, from 110,852,986 to 111,852,985.Chromosome XXq23p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q28111 Mb111.2 Mb111.4 Mb111.6 Mb111.8 MbPAK3: 110,944,285–111,227,361, forward strandPAK3CAPN6: 111,245,099–111,270,550, reverse strandCAPN6DCX: 111,293,779–111,412,192, reverse strandDCXSERTM2: 111,511,645–111,522,473, forward strandSERTM2ALG13: 111,665,811–111,766,130, forward strandALG13TRPC5: 111,768,011–112,082,776, reverse strandTRPC5Diagram of DCX: 7 exons on the reverse strand of chromosome XExon 7: 1 known disease-causing siteExon 5: 3 known disease-causing sitesExon 3: 16 known disease-causing sitesExon 2: 15 known disease-causing sitesExon 7: 111,293,779–111,301,743, 7,965 basesExon 6: 111,312,639–111,312,736, 98 basesExon 5: 111,330,904–111,331,041, 138 basesExon 4: 111,333,051–111,333,153, 103 basesExon 3: 111,400,990–111,401,330, 341 basesExon 2: 111,410,035–111,410,420, 386 basesExon 1: 111,412,138–111,412,192, 55 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.1 kb of the gene's 118.4 kb; 1,101 of those bases code for the protein.

How a genome test reads DCX

38

positions in DCX where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 118.4 kb of DCX, introns included, not only the 9.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DCX gene: doublecortin. Retrieved 16 October 2026, from https://dantelabs.com/genes/dcx

Vancouver

Dante Labs. DCX gene: doublecortin [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dcx

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