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Gene

ADD3

adducin 3

Summary

Cytogenetic location
10q25.1-q25.2
Coordinates
Chromosome 10: 110,007,984–110,135,565 (GRCh38)
Exons
15 exons across 127.6 kb
Protein
706 amino acids
Previous symbols
ADDL
MANE Select transcript
ENST00000356080.9NM_016824.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ADD3 yet. The test sequences your whole genome, so your data includes it all the same.

How ADD3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 10, with a bracket where ADD3 sits. ADD3 and 5 genes near it on chromosome 10, from 109,571,775 to 110,571,774.Chromosome 1010q25.1-q25.2p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.3109.6 Mb109.8 Mb110 Mb110.2 Mb110.4 MbXPNPEP1: 109,864,491–109,923,574, reverse strandXPNPEP1ADD3: 110,007,984–110,135,565, forward strandADD3MXI1: 110,207,546–110,287,916, forward strandMXI1SMNDC1: 110,289,425–110,305,001, reverse strandSMNDC1DUSP5: 110,497,907–110,511,544, forward strandDUSP5SMC3: 110,567,668–110,606,063, forward strandSMC3Diagram of ADD3: 15 exons on the forward strand of chromosome 10Exon 9: 1 known disease-causing siteExon 1: 110,007,984–110,008,299, 316 basesExon 2: 110,100,625–110,100,848, 224 basesExon 3: 110,112,777–110,112,915, 139 basesExon 4: 110,116,259–110,116,410, 152 basesExon 5: 110,117,342–110,117,422, 81 basesExon 6: 110,118,587–110,118,736, 150 basesExon 7: 110,119,211–110,119,354, 144 basesExon 8: 110,119,466–110,119,564, 99 basesExon 9: 110,122,110–110,122,292, 183 basesExon 10: 110,124,017–110,124,274, 258 basesExon 11: 110,125,826–110,125,945, 120 basesExon 12: 110,126,417–110,126,503, 87 basesExon 13: 110,130,363–110,130,486, 124 basesExon 14: 110,132,305–110,132,400, 96 basesExon 15: 110,133,326–110,135,565, 2,240 bases1510155′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.4 kb of the gene's 127.6 kb; 2,121 of those bases code for the protein.

How a genome test reads ADD3

1

position in ADD3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 127.6 kb of ADD3, introns included, not only the 4.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ADD3 gene: adducin 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/add3

Vancouver

Dante Labs. ADD3 gene: adducin 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/add3

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