Trait
Small nail
A nail that is diminished in length and width, i.e., underdeveloped nail.
Summary
- Also called
- Small nails, Hypoplastic nail, Hypoplastic nails, Nail hypoplasia
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test108 genes linked to Small nail
Changes in these genes cause rare conditions in which Small nail is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ARID1AAT-rich interaction domain 1A | Always | In 2 conditions |
| ARID2AT-rich interaction domain 2 | Always | In 2 conditions |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Always | In 1 condition |
| DSTdystonin | Always | In 1 condition |
| HEPHL1hephaestin like 1 | Always | In 1 condition |
| HOXA13homeobox A13 | Always | In 1 condition |
| HOXC13homeobox C13 | Always | In 1 condition |
| HYAL2hyaluronidase 2 | Always | In 1 condition |
| KCNN3potassium calcium-activated channel subfamily N member 3 | Always | In 1 condition |
| MED16mediator complex subunit 16 | Always | In 1 condition |
| NSDHLNAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL | Always | In 1 condition |
| PTBP1polypyrimidine tract binding protein 1 | Always | In 1 condition |
| RIPK4receptor interacting serine/threonine kinase 4 | Always | In 1 condition |
| RMP64ribonuclease MRP subunit p64 | Always | In 1 condition |
| ROR2ROR family WNT receptor 2 | Always | In 1 condition |
| TOMM7translocase of outer mitochondrial membrane 7 | Always | In 1 condition |
| TSPAN7tetraspanin 7 | Always | In 1 condition |
| UBAP2Lubiquitin associated protein 2 like | Always | In 1 condition |
| ARID1BAT-rich interaction domain 1B | Very often (80–99%) | In 1 condition |
| CTNNB1catenin beta 1 | Very often (80–99%) | In 1 condition |
| DPF2double PHD fingers 2 | Very often (80–99%) | In 1 condition |
| EVCEvC ciliary complex subunit 1 | Very often (80–99%) | In 2 conditions |
| EVC2EvC ciliary complex subunit 2 | Very often (80–99%) | In 2 conditions |
| SLC25A24solute carrier family 25 member 24 | Very often (80–99%) | In 1 condition |
| SMARCA4SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 | Very often (80–99%) | In 1 condition |
| SMARCAD1SNF2 related chromatin remodeling ATPase with DExD box 1 | Very often (80–99%) | In 2 conditions |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Very often (80–99%) | In 1 condition |
| SMARCC2SWI/SNF related BAF chromatin remodeling complex subunit C2 | Very often (80–99%) | In 1 condition |
| SMARCD1SWI/SNF related BAF chromatin remodeling complex subunit D1 | Very often (80–99%) | In 1 condition |
| SMARCE1SWI/SNF related BAF chromatin remodeling complex subunit E1 | Very often (80–99%) | In 1 condition |
| SOX11SRY-box transcription factor 11 | Very often (80–99%) | In 1 condition |
| SOX4SRY-box transcription factor 4 | Very often (80–99%) | In 1 condition |
| CKAP2Lcytoskeleton associated protein 2L | Often (30–79%) | In 1 condition |
| ELNelastin | Often (30–79%) | In 1 condition |
| FRAS1Fraser extracellular matrix complex subunit 1 | Often (30–79%) | In 1 condition |
| GDF5growth differentiation factor 5 | Often (30–79%) | In 1 condition |
| GPC3glypican 3 | Often (30–79%) | In 1 condition |
| GPC4glypican 4 | Often (30–79%) | In 1 condition |
| IHHIndian hedgehog signaling molecule | Often (30–79%) | In 1 condition |
| KCNH1potassium voltage-gated channel subfamily H member 1 | Often (30–79%) | In 1 condition |
Show 68 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| KIF15kinesin family member 15 | Often (30–79%) | In 1 condition |
| MCTP2multiple C2 and transmembrane domain containing 2 | Often (30–79%) | In 1 condition |
| MLXIPLMLX interacting protein like | Often (30–79%) | In 1 condition |
| ODC1ornithine decarboxylase 1 | Often (30–79%) | In 2 conditions |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Often (30–79%) | In 1 condition |
| PIGBphosphatidylinositol glycan anchor biosynthesis class B | Often (30–79%) | In 2 conditions |
| PIGVphosphatidylinositol glycan anchor biosynthesis class V | Often (30–79%) | In 2 conditions |
| PORCNporcupine O-acyltransferase | Often (30–79%) | In 1 condition |
| PPM1Dprotein phosphatase, Mg2+/Mn2+ dependent 1D | Often (30–79%) | In 1 condition |
| PRR12proline rich 12 | Often (30–79%) | In 1 condition |
| TWIST1twist family bHLH transcription factor 1 | Often (30–79%) | In 1 condition |
| ACTL6Bactin like 6B | Sometimes (5–29%) | In 1 condition |
| ALG12ALG12 alpha-1,6-mannosyltransferase | Sometimes (5–29%) | In 1 condition |
| ALOX12Barachidonate 12-lipoxygenase, 12R type | Sometimes (5–29%) | In 1 condition |
| ALOXE3arachidonate epidermal lipoxygenase 3 | Sometimes (5–29%) | In 1 condition |
| BICRABRD4 interacting chromatin remodeling complex associated protein | Sometimes (5–29%) | In 1 condition |
| CDIN1CDAN1 interacting nuclease 1 | Sometimes (5–29%) | In 1 condition |
| COL7A1collagen type VII alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| CWC27CWC27 spliceosome associated cyclophilin | Sometimes (5–29%) | In 2 conditions |
| DHX37DEAH-box helicase 37 | Sometimes (5–29%) | In 1 condition |
| DLK1delta like non-canonical Notch ligand 1 | Sometimes (5–29%) | In 1 condition |
| FOSL2FOS like 2, AP-1 transcription factor subunit | Sometimes (5–29%) | In 1 condition |
| GJB6gap junction protein beta 6 | Sometimes (5–29%) | In 2 conditions |
| HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 | Sometimes (5–29%) | In 1 condition |
| KMT2Dlysine methyltransferase 2D | Sometimes (5–29%) | In 1 condition |
| MEG3maternally expressed 3 | Sometimes (5–29%) | In 1 condition |
| OTUD5OTU deubiquitinase 5 | Sometimes (5–29%) | In 1 condition |
| PEX2peroxisomal biogenesis factor 2 | Sometimes (5–29%) | In 1 condition |
| PGAP2post-GPI attachment to proteins 2 | Sometimes (5–29%) | In 1 condition |
| PGAP3post-GPI attachment to proteins phospholipase 3 | Sometimes (5–29%) | In 1 condition |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Sometimes (5–29%) | In 1 condition |
| PIGOphosphatidylinositol glycan anchor biosynthesis class O | Sometimes (5–29%) | In 1 condition |
| PIGWphosphatidylinositol glycan anchor biosynthesis class W | Sometimes (5–29%) | In 1 condition |
| PIGYphosphatidylinositol glycan anchor biosynthesis class Y | Sometimes (5–29%) | In 1 condition |
| POP1POP1 ribonuclease P/MRP subunit | Sometimes (5–29%) | In 1 condition |
| REREarginine-glutamic acid dipeptide repeats | Sometimes (5–29%) | In 1 condition |
| RNU5B-1RNA, U5B small nuclear 1 | Sometimes (5–29%) | In 1 condition |
| RTL1retrotransposon Gag like 1 | Sometimes (5–29%) | In 1 condition |
| SIAH1siah E3 ubiquitin protein ligase 1 | Sometimes (5–29%) | In 1 condition |
| SPENspen family transcriptional repressor | Sometimes (5–29%) | In 1 condition |
| TMEM222transmembrane protein 222 | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| APC2APC regulator of Wnt signaling pathway 2 | Rarely (1–4%) | In 1 condition |
| NSD1nuclear receptor binding SET domain protein 1 | Rarely (1–4%) | In 2 conditions |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Rarely (1–4%) | In 1 condition |
| ADAMTSL2ADAMTS like 2 | Not recorded | In 1 condition |
| ALG3ALG3 alpha-1,3- mannosyltransferase | Not recorded | In 1 condition |
| ARHGAP31Rho GTPase activating protein 31 | Not recorded | In 1 condition |
| BHLHA9basic helix-loop-helix family member a9 | Not recorded | In 1 condition |
| CDH1cadherin 1 | Not recorded | In 1 condition |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Not recorded | In 1 condition |
| DOCK6dedicator of cytokinesis 6 | Not recorded | In 1 condition |
| EEDembryonic ectoderm development | Not recorded | In 1 condition |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Not recorded | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Not recorded | In 1 condition |
| MPLKIPM-phase specific PLK1 interacting protein | Not recorded | In 1 condition |
| NECTIN4nectin cell adhesion molecule 4 | Not recorded | In 1 condition |
| NHP2NHP2 ribonucleoprotein | Not recorded | In 1 condition |
| NOP10NOP10 ribonucleoprotein | Not recorded | In 1 condition |
| POC1APOC1 centriolar protein A | Not recorded | In 1 condition |
| POLR3ARNA polymerase III subunit A | Not recorded | In 1 condition |
| RLIMring finger protein, LIM domain interacting | Not recorded | In 1 condition |
| RSPO1R-spondin 1 | Not recorded | In 1 condition |
| STAMBPSTAM binding protein | Not recorded | In 1 condition |
| TP63tumor protein p63 | Not recorded | In 1 condition |
| TRRAPtransformation/transcription domain associated protein | Not recorded | In 1 condition |
| WDR73WD repeat domain 73 | Not recorded | In 1 condition |
| WNT10AWnt family member 10A | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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