Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

TRRAP

transformation/transcription domain associated protein

Summary

Cytogenetic location
7q22.1
Coordinates
Chromosome 7: 98,878,532–99,013,241 (GRCh38)
Exons
73 exons across 134.7 kb
Protein
3,873 amino acids
Also known as
TR-AP, PAF400, Tra1
MANE Select transcript
ENST00000456197.2NM_001375524.1
Locus type
Protein-coding

Curated reports relevant to this gene

No Genome Test report reads TRRAP yet. The test sequences your whole genome, so your data includes it all the same.

How TRRAP is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where TRRAP sits. TRRAP and 13 genes near it on chromosome 7, from 98,445,887 to 99,445,886.Chromosome 77q22.1p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.398.6 Mb98.8 Mb99 Mb99.2 Mb99.4 MbNPTX2: 98,617,254–98,629,870, forward strandNPTX2TMEM130: 98,846,478–98,870,771, reverse strandTMEM130TRRAP: 98,878,532–99,013,241, forward strandTRRAPSMURF1: 99,027,435–99,144,171, reverse strandSMURF1KPNA7: 99,173,572–99,250,075, reverse strandKPNA7MYH16: 99,272,839–99,311,132, forward strandMYH16ARPC1A: 99,325,879–99,366,527, forward strandARPC1A: 99,325,879–99,394,653, forward strandARPC1B: 99,374,226–99,398,124, forward strandARPC1BPDAP1: 99,392,048–99,408,831, reverse strandPDAP1BUD31: 99,408,610–99,419,618, forward strandBUD31PTCD1: 99,415,192–99,466,201, reverse strandPTCD1ATP5MF-PTCD1: 99,419,749–99,466,197, reverse strandCPSF4: 99,438,908–99,458,910, forward strandDiagram of TRRAP: 73 exons on the forward strand of chromosome 7Exon 5: 1 known disease-causing siteExon 23: 3 known disease-causing sitesExon 24: 2 known disease-causing sitesExon 25: 1 known disease-causing siteExon 27: 1 known disease-causing siteExon 40: 1 known disease-causing siteExon 41: 1 known disease-causing siteExon 45: 1 known disease-causing siteExon 59: 1 known disease-causing siteExon 63: 1 known disease-causing siteExon 66: 1 known disease-causing siteExon 1: 98,878,532–98,878,637, 106 basesExon 2: 98,881,090–98,881,250, 161 basesExon 3: 98,881,975–98,882,024, 50 basesExon 4: 98,890,335–98,890,445, 111 basesExon 5: 98,892,424–98,892,528, 105 basesExon 6: 98,893,798–98,893,881, 84 basesExon 7: 98,895,764–98,895,820, 57 basesExon 8: 98,897,741–98,897,866, 126 basesExon 9: 98,899,422–98,899,499, 78 basesExon 10: 98,899,679–98,899,767, 89 basesExon 11: 98,900,624–98,900,720, 97 basesExon 12: 98,903,379–98,903,517, 139 basesExon 13: 98,906,177–98,906,255, 79 basesExon 14: 98,908,728–98,908,962, 235 basesExon 15: 98,910,056–98,910,419, 364 basesExon 16: 98,910,510–98,910,607, 98 basesExon 17: 98,911,077–98,911,271, 195 basesExon 18: 98,912,022–98,912,213, 192 basesExon 19: 98,915,723–98,915,888, 166 basesExon 20: 98,917,423–98,917,679, 257 basesExon 21: 98,921,753–98,921,953, 201 basesExon 22: 98,925,112–98,925,263, 152 basesExon 23: 98,927,167–98,927,366, 200 basesExon 24: 98,929,989–98,930,206, 218 basesExon 25: 98,930,633–98,930,830, 198 basesExon 26: 98,931,405–98,931,665, 261 basesExon 27: 98,933,241–98,933,402, 162 basesExon 28: 98,935,579–98,935,675, 97 basesExon 29: 98,937,156–98,937,277, 122 basesExon 30: 98,937,650–98,937,820, 171 basesExon 31: 98,942,949–98,943,017, 69 basesExon 32: 98,945,747–98,945,800, 54 basesExon 33: 98,945,930–98,945,950, 21 basesExon 34: 98,948,221–98,948,340, 120 basesExon 35: 98,948,566–98,948,685, 120 basesExon 36: 98,949,417–98,949,581, 165 basesExon 37: 98,949,660–98,949,841, 182 basesExon 38: 98,950,064–98,950,262, 199 basesExon 39: 98,950,876–98,951,004, 129 basesExon 40: 98,953,167–98,953,433, 267 basesExon 41: 98,955,098–98,955,304, 207 basesExon 42: 98,956,146–98,956,304, 159 basesExon 43: 98,956,399–98,956,533, 135 basesExon 44: 98,957,981–98,958,091, 111 basesExon 45: 98,959,344–98,959,490, 147 basesExon 46: 98,961,261–98,961,474, 214 basesExon 47: 98,962,302–98,962,427, 126 basesExon 48: 98,964,629–98,964,775, 147 basesExon 49: 98,965,696–98,965,895, 200 basesExon 50: 98,967,041–98,967,162, 122 basesExon 51: 98,967,485–98,967,698, 214 basesExon 52: 98,970,112–98,970,291, 180 basesExon 53: 98,971,799–98,971,945, 147 basesExon 54: 98,976,149–98,976,268, 120 basesExon 55: 98,976,483–98,976,770, 288 basesExon 56: 98,976,939–98,977,076, 138 basesExon 57: 98,978,211–98,978,323, 113 basesExon 58: 98,978,769–98,978,904, 136 basesExon 59: 98,981,769–98,981,960, 192 basesExon 60: 98,983,264–98,983,459, 196 basesExon 61: 98,984,093–98,984,358, 266 basesExon 62: 98,984,944–98,985,044, 101 basesExon 63: 98,988,765–98,988,966, 202 basesExon 64: 98,990,455–98,990,619, 165 basesExon 65: 98,992,137–98,992,227, 91 basesExon 66: 98,993,538–98,993,737, 200 basesExon 67: 98,994,587–98,994,848, 262 basesExon 68: 99,004,190–99,004,415, 226 basesExon 69: 99,005,131–99,005,348, 218 basesExon 70: 99,008,377–99,008,561, 185 basesExon 71: 99,011,052–99,011,255, 204 basesExon 72: 99,011,341–99,011,535, 195 basesExon 73: 99,012,071–99,013,241, 1,171 bases1510152025303540455055606570735′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 12.7 kb of the gene's 134.7 kb; 11,622 of those bases code for the protein.

Sequencing TRRAP

16

positions in TRRAP where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 134.7 kb of TRRAP, introns included, not only the 12.7 kb of exons.

Traits linked to TRRAP

The Human Phenotype Ontology lists these as features of the rare conditions TRRAP can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TRRAP gene: transformation/transcription domain associated protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/trrap

Vancouver

Dante Labs. TRRAP gene: transformation/transcription domain associated protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/trrap

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test