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Gene

CDIN1

CDAN1 interacting nuclease 1

Summary

Cytogenetic location
15q14
Coordinates
Chromosome 15: 36,579,626–36,810,244 (GRCh38)
Exons
11 exons across 230.6 kb
Protein
281 amino acids
Also known as
HH114, MGC11326, FLJ22851
Previous symbols
C15orf41
MANE Select transcript
ENST00000566621.6NM_001321759.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Congenital Dyserythropoietic Anaemias

    • Congenital Dyserythropoietic Anaemia

      A group of conditions (types I to IV and related forms) caused by changes in genes such as CDAN1, CDIN1, SEC23B, KIF23, KLF1 and GATA1, mostly inherited recessively, with some dominant forms.

      • 1 GenCC submitter rates it definitive or strong
      What knowing changes

      A diagnosis guides monitoring and treatment of iron overload, which can develop even without transfusions; interferon-alpha can help in type I.

How CDIN1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 15, with a bracket where CDIN1 sits. CDIN1 and 1 gene near it on chromosome 15, from 36,194,935 to 37,194,934.Chromosome 1515q14p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q14q15.1q15.2q15.3q21.1q21.2q21.3q22.1q22.2q22.31q22.32q22.33q23q24.1q24.2q24.3q25.1q25.2q25.3q26.1q26.2q26.336.2 Mb36.4 Mb36.6 Mb36.8 Mb37 MbCDIN1: 36,579,626–36,810,244, forward strandCDIN1MEIS2: 36,889,204–37,102,646, reverse strandMEIS2Diagram of CDIN1: 11 exons on the forward strand of chromosome 15Exon 5: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 1: 36,579,626–36,579,961, 336 basesExon 2: 36,644,278–36,644,323, 46 basesExon 3: 36,645,223–36,645,287, 65 basesExon 4: 36,654,098–36,654,158, 61 basesExon 5: 36,657,833–36,657,905, 73 basesExon 6: 36,691,685–36,691,764, 80 basesExon 7: 36,692,126–36,692,175, 50 basesExon 8: 36,697,323–36,697,390, 68 basesExon 9: 36,709,223–36,709,288, 66 basesExon 10: 36,709,856–36,709,961, 106 basesExon 11: 36,808,324–36,810,244, 1,921 bases1246810115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.9 kb of the gene's 230.6 kb; 846 of those bases code for the protein.

How a genome test reads CDIN1

3

positions in CDIN1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 230.6 kb of CDIN1, introns included, not only the 2.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CDIN1 gene: CDAN1 interacting nuclease 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/cdin1

Vancouver

Dante Labs. CDIN1 gene: CDAN1 interacting nuclease 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/cdin1

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