Corneal Dystrophy
A group of inherited conditions affecting one or more layers of the cornea, including Fuchs endothelial dystrophy (often linked to a TCF4 repeat expansion), TGFBI-related granular and lattice dystrophies, and rarer types caused by genes such as SLC4A11, COL8A2, ZEB1 and CHST6.
Co se diagnózou změní
Carriers of TGFBI variants are generally advised to avoid laser refractive surgery (LASIK or PRK), which can make deposits worse; corneal transplant can restore vision in advanced disease.
Analyzované geny
Známé také jako
Corneal dystrophies; corneal dystrophy (disease)
Zahrnuje 57 příbuzných podtypů ↓Skrýt podtypy ↑
- autosomal dominant keratitis
- band keratopathy
- central cloudy dystrophy of François
- Chandler syndrome
- congenital hereditary endothelial dystrophy of cornea
- congenital hereditary endothelial dystrophy type I
- congenital stromal corneal dystrophy
- corneal dystrophy, Fuchs endothelial, 1
- corneal dystrophy, fuchs endothelial, 2
- corneal dystrophy, Fuchs endothelial, 3
- corneal dystrophy, Fuchs endothelial, 4
- corneal dystrophy, fuchs endothelial, 5
- corneal dystrophy, Fuchs endothelial, 6
- corneal dystrophy, fuchs endothelial, 7
- corneal dystrophy, Fuchs endothelial, 8
- corneal dystrophy, lattice type 3A
- corneal dystrophy, Meesmann, 1
- corneal dystrophy, Meesmann, 2
- corneal dystrophy, posterior polymorphous, 4
- corneal dystrophy, punctiform and polychromatic pre-descemet
- corneal endothelial dystrophy
- corneal granular dystrophy
- corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome
- epithelial and subepithelial corneal dystrophy
- epithelial basement membrane dystrophy
- epithelial recurrent erosion dystrophy
- epithelial-stromal TGFBI dystrophy
- Finnish type amyloidosis
- fleck corneal dystrophy
- Fuchs' endothelial dystrophy
- gelatinous drop-like corneal dystrophy
- granular corneal dystrophy type I
- granular corneal dystrophy type II
- Grayson-Wilbrandt corneal dystrophy
- hereditary benign intraepithelial dyskeratosis
- honey-droplet corneal dystrophy
- Judge Misch wright syndrome
- lattice corneal dystrophy
- lattice corneal dystrophy type I
- Lisch epithelial corneal dystrophy
- macular corneal dystrophy
- macular dystrophy, fenestrated sheen type
- Meesmann corneal dystrophy
- posterior amorphous corneal dystrophy
- posterior corneal dystrophy
- posterior polymorphous corneal dystrophy
- posterior polymorphous corneal dystrophy 1
- posterior polymorphous corneal dystrophy 2
- posterior polymorphous corneal dystrophy 3
- pre-descemet corneal dystrophy
- Reis-Bucklers corneal dystrophy
- Schnyder corneal dystrophy
- stromal corneal dystrophy
- subepithelial mucinous corneal dystrophy
- superficial corneal dystrophy
- Thiel-Behnke corneal dystrophy
- X-linked endothelial corneal dystrophy
