Trait

Cardiogenic shock

Severely decreased cardiac output with evidence of inadequate end-organ perfusion (i.e., tissue hypoxia) in the presence of adequate intravascular volume.

HPO HP:0030149

Also called: Cardiovascular shock
Body system: Abnormality of the cardiovascular system

Reference genomeGRCh38hg38

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9 genes linked to Cardiogenic shock

Changes in these genes cause rare conditions in which Cardiogenic shock is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
ABCC6ATP binding cassette subfamily C member 6	Always	In 1 condition
DNM1Ldynamin 1L	Always	In 1 condition
LMOD2leiomodin 2	Often (30–79%)	In 1 condition
MYL2myosin light chain 2	Often (30–79%)	In 1 condition
PSMB9proteasome 20S subunit beta 9	Often (30–79%)	In 1 condition
NAA10N-alpha-acetyltransferase 10, NatA catalytic subunit	Sometimes (5–29%)	In 1 condition
RPL3Lribosomal protein L3 like	Sometimes (5–29%)	In 1 condition
SDHAsuccinate dehydrogenase complex flavoprotein subunit A	Sometimes (5–29%)	In 1 condition
ATRXATRX chromatin remodeler	Rarely (1–4%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Shock

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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