Trait
Narrow chest
Reduced width of the chest from side to side, associated with a reduced distance from the sternal notch to the tip of the shoulder.
Summary
- Also called
- Low chest circumference, Narrow shoulders, Narrow thorax, Reduced anterior-posterior chest diameter
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test138 genes linked to Narrow chest
Changes in these genes cause rare conditions in which Narrow chest is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| BNIP1BCL2 interacting protein 1 | Always | In 1 condition |
| CEP120centrosomal protein 120 | Always | In 2 conditions |
| CILK1ciliogenesis associated kinase 1 | Always | In 2 conditions |
| CREB3L1cAMP responsive element binding protein 3 like 1 | Always | In 1 condition |
| CUL7cullin 7 | Always | In 1 condition |
| DONSONDNA replication fork stabilization factor DONSON | Always | In 2 conditions |
| DSTdystonin | Always | In 1 condition |
| DYNC2LI1dynein cytoplasmic 2 light intermediate chain 1 | Always | In 3 conditions |
| FBN1fibrillin 1 | Always | In 2 conditions |
| FGFR3fibroblast growth factor receptor 3 | Always | In 5 conditions |
| FLNAfilamin A | Always | In 4 conditions |
| HHAThedgehog acyltransferase | Always | In 2 conditions |
| IFT122intraflagellar transport 122 | Always | In 2 conditions |
| IFT140intraflagellar transport 140 | Always | In 3 conditions |
| IFT43intraflagellar transport 43 | Always | In 2 conditions |
| IFT52intraflagellar transport 52 | Always | In 2 conditions |
| KAT6Alysine acetyltransferase 6A | Always | In 1 condition |
| KIAA0753KIAA0753 | Always | In 2 conditions |
| MYOD1myogenic differentiation 1 | Always | In 1 condition |
| PAM16presequence translocase associated motor 16 | Always | In 1 condition |
| PAN2poly(A) specific ribonuclease subunit PAN2 | Always | In 1 condition |
| PLCB3phospholipase C beta 3 | Always | In 1 condition |
| PPIBpeptidylprolyl isomerase B | Always | In 1 condition |
| PTH1Rparathyroid hormone 1 receptor | Always | In 2 conditions |
| SEC23ASEC23 homolog A, COPII component | Always | In 2 conditions |
| SLC35D1solute carrier family 35 member D1 | Always | In 2 conditions |
| SLC37A4solute carrier family 37 member 4 | Always | In 1 condition |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| TBX5T-box transcription factor 5 | Always | In 1 condition |
| TOMM7translocase of outer mitochondrial membrane 7 | Always | In 1 condition |
| TRIP11thyroid hormone receptor interactor 11 | Always | In 4 conditions |
| TTC21Btetratricopeptide repeat domain 21B | Always | In 2 conditions |
| WDR19WD repeat domain 19 | Always | In 4 conditions |
| WDR35WD repeat domain 35 | Always | In 4 conditions |
| CASRcalcium sensing receptor | Very often (80–99%) | In 2 conditions |
| CLCN7Cl-/H+ antiporter 7 | Very often (80–99%) | In 1 condition |
| COL11A1collagen type XI alpha 1 chain | Very often (80–99%) | In 2 conditions |
| COL11A2collagen type XI alpha 2 chain | Very often (80–99%) | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Very often (80–99%) | In 3 conditions |
| DYNC2H1dynein cytoplasmic 2 heavy chain 1 | Very often (80–99%) | In 2 conditions |
Show 98 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| DYNC2I1dynein 2 intermediate chain 1 | Very often (80–99%) | In 3 conditions |
| DYNC2I2dynein 2 intermediate chain 2 | Very often (80–99%) | In 3 conditions |
| EVCEvC ciliary complex subunit 1 | Very often (80–99%) | In 2 conditions |
| EVC2EvC ciliary complex subunit 2 | Very often (80–99%) | In 2 conditions |
| FLNBfilamin B | Very often (80–99%) | In 3 conditions |
| GLI1GLI family zinc finger 1 | Very often (80–99%) | In 1 condition |
| IFT172intraflagellar transport 172 | Very often (80–99%) | In 1 condition |
| IFT80intraflagellar transport 80 | Very often (80–99%) | In 3 conditions |
| INPPL1inositol polyphosphate phosphatase like 1 | Very often (80–99%) | In 3 conditions |
| LBRlamin B receptor | Very often (80–99%) | In 2 conditions |
| OSTM1osteoclastogenesis associated transmembrane protein 1 | Very often (80–99%) | In 1 condition |
| PRKACAprotein kinase cAMP-activated catalytic subunit alpha | Very often (80–99%) | In 1 condition |
| PRKACBprotein kinase cAMP-activated catalytic subunit beta | Very often (80–99%) | In 2 conditions |
| RUNX2RUNX family transcription factor 2 | Very often (80–99%) | In 2 conditions |
| SLC26A2solute carrier family 26 member 2 | Very often (80–99%) | In 3 conditions |
| SNX10sorting nexin 10 | Very often (80–99%) | In 1 condition |
| SOX9SRY-box transcription factor 9 | Very often (80–99%) | In 1 condition |
| TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | Very often (80–99%) | In 1 condition |
| TMCO1transmembrane and coiled-coil domains 1 | Very often (80–99%) | In 2 conditions |
| TNFSF11TNF superfamily member 11 | Very often (80–99%) | In 1 condition |
| TRPV4transient receptor potential cation channel subfamily V member 4 | Very often (80–99%) | In 2 conditions |
| TRPV6transient receptor potential cation channel subfamily V member 6 | Very often (80–99%) | In 2 conditions |
| ABCC9ATP binding cassette subfamily C member 9 | Often (30–79%) | In 2 conditions |
| ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3 | Often (30–79%) | In 1 condition |
| ATP7AATPase copper transporting alpha | Often (30–79%) | In 3 conditions |
| CANT1calcium activated nucleotidase 1 | Often (30–79%) | In 1 condition |
| CCBE1collagen and calcium binding EGF domains 1 | Often (30–79%) | In 1 condition |
| CCDC47coiled-coil domain containing 47 | Often (30–79%) | In 1 condition |
| DCHS1dachsous cadherin-related 1 | Often (30–79%) | In 1 condition |
| DDR2discoidin domain receptor tyrosine kinase 2 | Often (30–79%) | In 1 condition |
| DLG3discs large MAGUK scaffold protein 3 | Often (30–79%) | In 1 condition |
| DYNLT2Bdynein light chain Tctex-type 2B | Often (30–79%) | In 1 condition |
| FAT4FAT atypical cadherin 4 | Often (30–79%) | In 2 conditions |
| FGF4fibroblast growth factor 4 | Often (30–79%) | In 1 condition |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Often (30–79%) | In 1 condition |
| GPX4glutathione peroxidase 4 | Often (30–79%) | In 2 conditions |
| HSPG2heparan sulfate proteoglycan 2 | Often (30–79%) | In 1 condition |
| IHHIndian hedgehog signaling molecule | Often (30–79%) | In 2 conditions |
| KCNJ8potassium inwardly rectifying channel subfamily J member 8 | Often (30–79%) | In 1 condition |
| KYNUkynureninase | Often (30–79%) | In 1 condition |
| MESDmesoderm development LRP chaperone | Often (30–79%) | In 1 condition |
| NEK9NIMA related kinase 9 | Often (30–79%) | In 1 condition |
| POLR3ARNA polymerase III subunit A | Often (30–79%) | In 1 condition |
| RMP64ribonuclease MRP subunit p64 | Often (30–79%) | In 1 condition |
| RMRPRNA component of mitochondrial RNA processing endoribonuclease | Often (30–79%) | In 2 conditions |
| TWIST1twist family bHLH transcription factor 1 | Often (30–79%) | In 1 condition |
| WDR11WD repeat domain 11 | Often (30–79%) | In 1 condition |
| ZBTB20zinc finger and BTB domain containing 20 | Often (30–79%) | In 2 conditions |
| ACTA1actin alpha 1, skeletal muscle | Sometimes (5–29%) | In 2 conditions |
| ACTG2actin gamma 2, smooth muscle | Sometimes (5–29%) | In 1 condition |
| CFAP410cilia and flagella associated protein 410 | Sometimes (5–29%) | In 1 condition |
| CFL2cofilin 2 | Sometimes (5–29%) | In 1 condition |
| DDX3XDEAD-box helicase 3 X-linked | Sometimes (5–29%) | In 1 condition |
| DLK1delta like non-canonical Notch ligand 1 | Sometimes (5–29%) | In 1 condition |
| GAD1glutamate decarboxylase 1 | Sometimes (5–29%) | In 1 condition |
| KBTBD13kelch repeat and BTB domain containing 13 | Sometimes (5–29%) | In 1 condition |
| KLHL41kelch like family member 41 | Sometimes (5–29%) | In 3 conditions |
| LMNAlamin A/C | Sometimes (5–29%) | In 1 condition |
| LMOD3leiomodin 3 | Sometimes (5–29%) | In 1 condition |
| MED12mediator complex subunit 12 | Sometimes (5–29%) | In 1 condition |
| MEG3maternally expressed 3 | Sometimes (5–29%) | In 1 condition |
| MYPNmyopalladin | Sometimes (5–29%) | In 1 condition |
| NEBnebulin | Sometimes (5–29%) | In 2 conditions |
| PCNTpericentrin | Sometimes (5–29%) | In 1 condition |
| PIGNphosphatidylinositol glycan anchor biosynthesis class N | Sometimes (5–29%) | In 2 conditions |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| PORcytochrome p450 oxidoreductase | Sometimes (5–29%) | In 2 conditions |
| PUF60poly(U) binding splicing factor 60 | Sometimes (5–29%) | In 1 condition |
| RTL1retrotransposon Gag like 1 | Sometimes (5–29%) | In 1 condition |
| SKISKI proto-oncogene | Sometimes (5–29%) | In 1 condition |
| TCTN2tectonic family member 2 | Sometimes (5–29%) | In 1 condition |
| TPM2tropomyosin 2 | Sometimes (5–29%) | In 2 conditions |
| TPM3tropomyosin 3 | Sometimes (5–29%) | In 1 condition |
| UPF3BUPF3B regulator of nonsense mediated mRNA decay | Sometimes (5–29%) | In 1 condition |
| XYLT1xylosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| CTSKcathepsin K | Rarely (1–4%) | In 1 condition |
| AGRNagrin | Not recorded | In 1 condition |
| B3GAT3beta-1,3-glucuronyltransferase 3 | Not recorded | In 1 condition |
| B4GALT7beta-1,4-galactosyltransferase 7 | Not recorded | In 1 condition |
| BCORBCL6 corepressor | Not recorded | In 1 condition |
| CHST3carbohydrate sulfotransferase 3 | Not recorded | In 1 condition |
| CRTAPcartilage associated protein | Not recorded | In 1 condition |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Not recorded | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Not recorded | In 1 condition |
| IFT81intraflagellar transport 81 | Not recorded | In 1 condition |
| INTUinturned planar cell polarity protein | Not recorded | In 1 condition |
| ITGA3integrin subunit alpha 3 | Not recorded | In 1 condition |
| KIAA0586KIAA0586 | Not recorded | In 1 condition |
| NAA10N-alpha-acetyltransferase 10, NatA catalytic subunit | Not recorded | In 1 condition |
| NEK1NIMA related kinase 1 | Not recorded | In 1 condition |
| ORC6origin recognition complex subunit 6 | Not recorded | In 1 condition |
| PCGF2polycomb group ring finger 2 | Not recorded | In 1 condition |
| RPS19ribosomal protein S19 | Not recorded | In 1 condition |
| SBDSSBDS ribosome maturation factor | Not recorded | In 1 condition |
| SERPINH1serpin family H member 1 | Not recorded | In 1 condition |
| SLC9A6solute carrier family 9 member A6 | Not recorded | In 1 condition |
| SRP54signal recognition particle 54 | Not recorded | In 1 condition |
| ZC4H2zinc finger C4H2-type containing | Not recorded | In 2 conditions |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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