Trait
Enlarged kidney
An abnormal increase in the size of the kidney.
Summary
- Also called
- Large kidneys, Nephromegaly, Renal enlargement
- Body system
- Abnormality of the genitourinary system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test48 genes linked to Enlarged kidney
Changes in these genes cause rare conditions in which Enlarged kidney is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CD81CD81 molecule | Always | In 1 condition |
| CPT2carnitine palmitoyltransferase 2 | Always | In 1 condition |
| FLVCR1FLVCR choline and heme transporter 1 | Always | In 1 condition |
| VPS45vacuolar protein sorting 45 homolog | Always | In 1 condition |
| WT1WT1 transcription factor | Always | In 2 conditions |
| DZIP1LDAZ interacting zinc finger protein 1 like | Very often (80–99%) | In 2 conditions |
| PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin | Very often (80–99%) | In 2 conditions |
| ANKS6ankyrin repeat and sterile alpha motif domain containing 6 | Often (30–79%) | In 1 condition |
| DICER1dicer 1, ribonuclease III | Often (30–79%) | In 1 condition |
| FAHfumarylacetoacetate hydrolase | Often (30–79%) | In 1 condition |
| INSRinsulin receptor | Often (30–79%) | In 2 conditions |
| MYRFmyelin regulatory factor | Often (30–79%) | In 1 condition |
| NEK8NIMA related kinase 8 | Often (30–79%) | In 4 conditions |
| NPHP3nephrocystin 3 | Often (30–79%) | In 3 conditions |
| PRKAG2protein kinase AMP-activated non-catalytic subunit gamma 2 | Often (30–79%) | In 1 condition |
| RBSNrabenosyn, RAB effector | Often (30–79%) | In 1 condition |
| SAA1serum amyloid A1 | Often (30–79%) | In 1 condition |
| SLC37A4solute carrier family 37 member 4 | Often (30–79%) | In 2 conditions |
| ZIC3Zic family zinc finger 3 | Often (30–79%) | In 2 conditions |
| ADNPactivity dependent neuroprotector homeobox | Sometimes (5–29%) | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Sometimes (5–29%) | In 1 condition |
| ALG5ALG5 dolichyl-phosphate beta-glucosyltransferase | Sometimes (5–29%) | In 1 condition |
| ALG9ALG9 alpha-1,2-mannosyltransferase | Sometimes (5–29%) | In 2 conditions |
| BICC1BicC family RNA binding protein 1 | Sometimes (5–29%) | In 1 condition |
| DNAJB11DnaJ heat shock protein family (Hsp40) member B11 | Sometimes (5–29%) | In 1 condition |
| FIBPFGF1 intracellular binding protein | Sometimes (5–29%) | In 1 condition |
| GANABglucosidase II alpha subunit | Sometimes (5–29%) | In 1 condition |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Sometimes (5–29%) | In 1 condition |
| IFT140intraflagellar transport 140 | Sometimes (5–29%) | In 1 condition |
| NAA10N-alpha-acetyltransferase 10, NatA catalytic subunit | Sometimes (5–29%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| PKD1polycystin 1, transient receptor potential channel interacting | Sometimes (5–29%) | In 1 condition |
| PKD2polycystin 2, transient receptor potential cation channel | Sometimes (5–29%) | In 1 condition |
| SLC29A3solute carrier family 29 member 3 | Sometimes (5–29%) | In 1 condition |
| TCTN2tectonic family member 2 | Sometimes (5–29%) | In 1 condition |
| TRPV6transient receptor potential cation channel subfamily V member 6 | Sometimes (5–29%) | In 1 condition |
| TULP3TUB like protein 3 | Sometimes (5–29%) | In 1 condition |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Sometimes (5–29%) | In 2 conditions |
| BMPERBMP binding endothelial regulator | Not recorded | In 1 condition |
| CDKN1Ccyclin dependent kinase inhibitor 1C | Not recorded | In 1 condition |
Show 8 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| CILK1ciliogenesis associated kinase 1 | Not recorded | In 1 condition |
| DYNC2H1dynein cytoplasmic 2 heavy chain 1 | Not recorded | In 1 condition |
| G6PC1glucose-6-phosphatase catalytic subunit 1 | Not recorded | In 1 condition |
| GPC3glypican 3 | Not recorded | In 1 condition |
| IGF2insulin like growth factor 2 | Not recorded | In 1 condition |
| INVSinversin | Not recorded | In 1 condition |
| KCNQ1potassium voltage-gated channel subfamily Q member 1 | Not recorded | In 1 condition |
| KCNQ1OT1KCNQ1 opposite strand/antisense transcript 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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