Trait
Abnormal dental position
Clinical name: Tooth malposition
Abnormal alignment, positioning, or spacing of the teeth, i.e., misaligned teeth.
Summary
- Also called
- Abnormal teeth spacing, Abnormality of alignment of teeth, Abnormality of position of teeth, Abnormality of teeth spacing, Crooked teeth, Malaligned teeth, Malposition of teeth, Malpositioned teeth, Misalignment of teeth, Teeth, malposition
- Body system
- Abnormality of head or neck
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test28 genes linked to Abnormal dental position
Changes in these genes cause rare conditions in which Abnormal dental position is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AEBP1AE binding protein 1 | Always | In 2 conditions |
| SMARCD2SWI/SNF related BAF chromatin remodeling complex subunit D2 | Always | In 1 condition |
| SOSTsclerostin | Always | In 1 condition |
| ZEB2zinc finger E-box binding homeobox 2 | Always | In 3 conditions |
| SMCHD1structural maintenance of chromosomes flexible hinge domain containing 1 | Very often (80–99%) | In 1 condition |
| TCF4transcription factor 4 | Very often (80–99%) | In 1 condition |
| BCAS3BCAS3 microtubule associated cell migration factor | Often (30–79%) | In 1 condition |
| BCORBCL6 corepressor | Often (30–79%) | In 2 conditions |
| BPTFbromodomain PHD finger transcription factor | Often (30–79%) | In 1 condition |
| EXOSC5exosome component 5 | Often (30–79%) | In 1 condition |
| FLNAfilamin A | Often (30–79%) | In 2 conditions |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Often (30–79%) | In 1 condition |
| POLR2ARNA polymerase II subunit A | Often (30–79%) | In 1 condition |
| PSMD12proteasome 26S subunit, non-ATPase 12 | Often (30–79%) | In 1 condition |
| RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1 | Often (30–79%) | In 1 condition |
| RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2 | Often (30–79%) | In 2 conditions |
| RIC1RIC1 partner of RAB6A GEF complex | Often (30–79%) | In 1 condition |
| CA2carbonic anhydrase 2 | Sometimes (5–29%) | In 1 condition |
| CHSY1chondroitin sulfate synthase 1 | Sometimes (5–29%) | In 1 condition |
| CNOT2CCR4-NOT transcription complex subunit 2 | Sometimes (5–29%) | In 1 condition |
| USP9Xubiquitin specific peptidase 9 X-linked | Sometimes (5–29%) | In 1 condition |
| RNU4-2RNA, U4 small nuclear 2 | Rarely (1–4%) | In 1 condition |
| ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10 | Not recorded | In 1 condition |
| ANKHANKH inorganic pyrophosphate transport regulator | Not recorded | In 1 condition |
| FBN1fibrillin 1 | Not recorded | In 1 condition |
| NAA10N-alpha-acetyltransferase 10, NatA catalytic subunit | Not recorded | In 1 condition |
| PTH1Rparathyroid hormone 1 receptor | Not recorded | In 1 condition |
| XRCC4X-ray repair cross complementing 4 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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