Gene
DYNC2I1
dynein 2 intermediate chain 1
- HGNC 21862↗(opens in a new tab)
- Ensembl gene ENSG00000126870↗(opens in a new tab)
- NCBI Gene 55112↗(opens in a new tab)
Summary
- Cytogenetic location
- 7q36.3
- Coordinates
- Chromosome 7: 158,856,558–158,946,189 (GRCh38)
- Exons
- 25 exons across 89.6 kb
- Protein
- 1,066 amino acids
- Also known as
- FLJ10300, FAP163, CFAP163, DIC6
- Previous symbols
- WDR60
- MANE Select transcript
- ENST00000407559.8NM_018051.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads DYNC2I1 yet. The test sequences your whole genome, so your data includes it all the same.
How DYNC2I1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.8 kb of the gene's 89.6 kb; 3,201 of those bases code for the protein.
How a genome test reads DYNC2I1
25
positions in DYNC2I1 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 89.6 kb of DYNC2I1, introns included, not only the 3.8 kb of exons.
Traits linked to DYNC2I1
The Human Phenotype Ontology lists these as features of the rare conditions DYNC2I1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Big calvaria
- Cleft upper lip
- Depressed nasal bridge
- Eye folds
- Frontal bossing
- Little lower jaw
- Long philtrum
- Wide nose
Show 3 more traits
Abnormality of the genitourinary system
- Ambiguous external genitalia
- Double uterus
- Hydronephrosis
- Small kidneys
- Underdeveloped penis
- Undescended testes
- Urethrovaginal fistula
- Cystic kidney disease
Show 3 more traits
Abnormality of the digestive system
- Abdominal bloating
- Excessive buildup of connective tissue and scarring of liver at birth
- Abnormal anus position
- Abnormality of the liver
- Absent anus
- Birth defect in which part of esophagus did not develop
- Feeding difficulties in infancy
- Omphalocele
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). DYNC2I1 gene: dynein 2 intermediate chain 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/dync2i1
Dante Labs. DYNC2I1 gene: dynein 2 intermediate chain 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dync2i1
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