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Gene

DYNC2LI1

dynein cytoplasmic 2 light intermediate chain 1

Summary

Cytogenetic location
2p21
Coordinates
Chromosome 2: 43,774,039–43,810,010 (GRCh38)
Exons
13 exons across 36 kb
Protein
351 amino acids
Also known as
D2LIC, LIC3, CGI-60, DKFZP564A033
MANE Select transcript
ENST00000260605.12NM_016008.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads DYNC2LI1 yet. The test sequences your whole genome, so your data includes it all the same.

How DYNC2LI1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where DYNC2LI1 sits. DYNC2LI1 and 9 genes near it on chromosome 2, from 43,292,025 to 44,292,024.Chromosome 22p21p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.343.4 Mb43.6 Mb43.8 Mb44 Mb44.2 MbTHADA: 43,230,126–43,596,070, reverse strandTHADAPLEKHH2: 43,637,249–43,767,987, forward strandPLEKHH2C1GALT1C1L: 43,675,151–43,676,429, reverse strandC1GALT1C1LDYNC2LI1: 43,774,039–43,810,010, forward strandDYNC2LI1ABCG5: 43,806,213–43,838,865, reverse strandABCG5ABCG8: 43,831,942–43,882,988, forward strandABCG8LRPPRC: 43,886,224–43,996,226, reverse strandLRPPRCPPM1B: 44,167,969–44,244,384, forward strandPPM1B: 44,168,851–44,320,310, forward strandSLC3A1: 44,275,458–44,322,674, forward strandSLC3A1Diagram of DYNC2LI1: 13 exons on the forward strand of chromosome 2Exon 6: 2 known disease-causing sitesExon 13: 1 known disease-causing siteExon 1: 43,774,039–43,774,146, 108 basesExon 2: 43,776,782–43,776,899, 118 basesExon 3: 43,783,520–43,783,554, 35 basesExon 4: 43,787,181–43,787,250, 70 basesExon 5: 43,789,633–43,789,721, 89 basesExon 6: 43,794,457–43,794,643, 187 basesExon 7: 43,795,890–43,795,958, 69 basesExon 8: 43,796,718–43,796,795, 78 basesExon 9: 43,800,841–43,800,917, 77 basesExon 10: 43,801,639–43,801,709, 71 basesExon 11: 43,804,642–43,804,739, 98 basesExon 12: 43,805,154–43,805,246, 93 basesExon 13: 43,809,705–43,810,010, 306 bases124681012135′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.4 kb of the gene's 36 kb; 1,056 of those bases code for the protein.

How a genome test reads DYNC2LI1

4

positions in DYNC2LI1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 36 kb of DYNC2LI1, introns included, not only the 1.4 kb of exons.

Traits linked to DYNC2LI1

The Human Phenotype Ontology lists these as features of the rare conditions DYNC2LI1 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DYNC2LI1 gene: dynein cytoplasmic 2 light intermediate chain 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/dync2li1

Vancouver

Dante Labs. DYNC2LI1 gene: dynein cytoplasmic 2 light intermediate chain 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dync2li1

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