AtlasGene
DYNC2I2
dynein 2 intermediate chain 2
- HGNC 28296↗(opens in a new tab)
- Ensembl gene ENSG00000119333↗(opens in a new tab)
- NCBI Gene 89891↗(opens in a new tab)
Summary
- Cytogenetic location
- 9q34.11
- Coordinates
- Chromosome 9: 128,633,653–128,656,847 (GRCh38)
- Exons
- 9 exons across 23.2 kb
- Protein
- 536 amino acids
- Also known as
- DIC5, MGC20486, bA216B9.3, FAP133, CFAP133
- Previous symbols
- WDR34
- MANE Select transcript
- ENST00000372715.7NM_052844.4
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
AtlasThis page as data
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No Genome Test report reads DYNC2I2 yet. The test sequences your whole genome, so your data includes it all the same.
How DYNC2I2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.8 kb of the gene's 23.2 kb; 1,611 of those bases code for the protein.
Sequencing DYNC2I2
6Low
How hard DYNC2I2 is to sequence with short reads, out of 100Each bar is the share of DYNC2I2's exon bases in that kind of difficult region. The score weighs them by how much each costs a short-read call: 0 when no base is in any, 100 when every base is in all of them.
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. Weight 35%.0%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. Weight 30%.0%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. Weight 15%.0%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. Weight 10%.55%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. Weight 10%.0%
45
positions in DYNC2I2 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 23.2 kb of DYNC2I2, introns included, not only the 1.8 kb of exons.
Traits linked to DYNC2I2
The Human Phenotype Ontology lists these as features of the rare conditions DYNC2I2 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Big calvaria
- Cleft upper lip
- Depressed nasal bridge
- Eye folds
- Frontal bossing
- Little lower jaw
- Long philtrum
- Wide nose
Show 3 more traits
Abnormality of limbs
- Abnormality of the wide portion of a long bone
- Short foot
- Short palm
- Smaller or shorter than typical limbs
- Extra little finger
- Short fingers or toes
- Extra thumb
- Extra toe attached near the little toe
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.17-8666dff2.
Cite this page
Dante Labs. (n.d.). DYNC2I2 gene: dynein 2 intermediate chain 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/dync2i2
Dante Labs. DYNC2I2 gene: dynein 2 intermediate chain 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dync2i2
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