Trait
Bloody nose
Clinical name: Epistaxis
Epistaxis, or nosebleed, refers to a hemorrhage localized in the nose.
Summary
- Also called
- Frequent nosebleeds, Nose bleed, Nose bleeding, Nosebleed, Nasal haemorrhage, Nasal hemorrhage
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Bloody nose, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test110 genes linked to Bloody nose
Changes in these genes cause rare conditions in which Bloody nose is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| APOLD1apolipoprotein L domain containing 1 | Always | In 1 condition |
| ATXN7L3ataxin 7 like 3 | Always | In 1 condition |
| BLOC1S5biogenesis of lysosomal organelles complex 1 subunit 5 | Always | In 1 condition |
| CEBPECCAAT enhancer binding protein epsilon | Always | In 1 condition |
| DTNBP1dystrobrevin binding protein 1 | Always | In 1 condition |
| F7coagulation factor VII | Always | In 2 conditions |
| GFI1Bgrowth factor independent 1B transcriptional repressor | Always | In 2 conditions |
| GGCXgamma-glutamyl carboxylase | Always | In 3 conditions |
| HMOX1heme oxygenase 1 | Always | In 1 condition |
| ITGA2Bintegrin subunit alpha 2b | Always | In 2 conditions |
| MARK2microtubule affinity regulating kinase 2 | Always | In 1 condition |
| OAS22'-5'-oligoadenylate synthetase 2 | Always | In 1 condition |
| PLCG1phospholipase C gamma 1 | Always | In 1 condition |
| PRKACGprotein kinase cAMP-activated catalytic subunit gamma | Always | In 1 condition |
| RASGRP2RAS guanyl releasing protein 2 | Always | In 1 condition |
| TBXA2Rthromboxane A2 receptor | Always | In 1 condition |
| ACVRL1activin A receptor like type 1 | Very often (80–99%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Very often (80–99%) | In 1 condition |
| ENGendoglin | Very often (80–99%) | In 1 condition |
| EPORerythropoietin receptor | Very often (80–99%) | In 1 condition |
| FGAfibrinogen alpha chain | Very often (80–99%) | In 4 conditions |
| FGBfibrinogen beta chain | Very often (80–99%) | In 4 conditions |
| FGGfibrinogen gamma chain | Very often (80–99%) | In 4 conditions |
| GDF2growth differentiation factor 2 | Very often (80–99%) | In 1 condition |
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Very often (80–99%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Very often (80–99%) | In 1 condition |
| JAK2Janus kinase 2 | Very often (80–99%) | In 1 condition |
| LYSTlysosomal trafficking regulator | Very often (80–99%) | In 2 conditions |
| PRTN3proteinase 3 | Very often (80–99%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Very often (80–99%) | In 2 conditions |
| SMAD4SMAD family member 4 | Very often (80–99%) | In 2 conditions |
| ANO6anoctamin 6 | Often (30–79%) | In 1 condition |
| ATP8B1ATPase phospholipid transporting 8B1 | Often (30–79%) | In 1 condition |
| BCORBCL6 corepressor | Often (30–79%) | In 1 condition |
| F10coagulation factor X | Often (30–79%) | In 2 conditions |
| F11coagulation factor XI | Often (30–79%) | In 1 condition |
| F2coagulation factor II, thrombin | Often (30–79%) | In 2 conditions |
| F5coagulation factor V | Often (30–79%) | In 2 conditions |
| F8coagulation factor VIII | Often (30–79%) | In 3 conditions |
| FIP1L1factor interacting with PAPOLA and CPSF1 | Often (30–79%) | In 1 condition |
Show 70 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| GALEUDP-galactose-4-epimerase | Often (30–79%) | In 1 condition |
| GNEglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | Often (30–79%) | In 1 condition |
| GP1BAglycoprotein Ib platelet subunit alpha | Often (30–79%) | In 3 conditions |
| HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 | Often (30–79%) | In 1 condition |
| HPS5HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 | Often (30–79%) | In 1 condition |
| HPS6HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 | Often (30–79%) | In 1 condition |
| IRF2BP2interferon regulatory factor 2 binding protein 2 | Often (30–79%) | In 1 condition |
| LMAN1lectin, mannose binding 1 | Often (30–79%) | In 1 condition |
| LMX1BLIM homeobox transcription factor 1 beta | Often (30–79%) | In 1 condition |
| MCFD2multiple coagulation factor deficiency 2, ER cargo receptor complex subunit | Often (30–79%) | In 2 conditions |
| NABP1nucleic acid binding protein 1 | Often (30–79%) | In 1 condition |
| NBEAL2neurobeachin like 2 | Often (30–79%) | In 2 conditions |
| NPM1nucleophosmin 1 | Often (30–79%) | In 1 condition |
| NUMA1nuclear mitotic apparatus protein 1 | Often (30–79%) | In 1 condition |
| PMLPML nuclear body scaffold | Often (30–79%) | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Often (30–79%) | In 1 condition |
| RARAretinoic acid receptor alpha | Often (30–79%) | In 1 condition |
| SOX17SRY-box transcription factor 17 | Often (30–79%) | In 1 condition |
| STAT3signal transducer and activator of transcription 3 | Often (30–79%) | In 1 condition |
| STAT5Bsignal transducer and activator of transcription 5B | Often (30–79%) | In 1 condition |
| STIM1stromal interaction molecule 1 | Often (30–79%) | In 1 condition |
| STXBP1syntaxin binding protein 1 | Often (30–79%) | In 1 condition |
| TBL1XR1TBL1X/Y related 1 | Often (30–79%) | In 1 condition |
| VWFvon Willebrand factor | Often (30–79%) | In 3 conditions |
| ZBTB16zinc finger and BTB domain containing 16 | Often (30–79%) | In 1 condition |
| ACTN1actinin alpha 1 | Sometimes (5–29%) | In 2 conditions |
| BLOC1S3biogenesis of lysosomal organelles complex 1 subunit 3 | Sometimes (5–29%) | In 1 condition |
| CACNA1Dcalcium voltage-gated channel subunit alpha1 D | Sometimes (5–29%) | In 1 condition |
| CDC42BPBCDC42 binding protein kinase beta | Sometimes (5–29%) | In 1 condition |
| CLCN2chloride voltage-gated channel 2 | Sometimes (5–29%) | In 1 condition |
| CYP11B1cytochrome P450 family 11 subfamily B member 1 | Sometimes (5–29%) | In 1 condition |
| CYP11B2cytochrome P450 family 11 subfamily B member 2 | Sometimes (5–29%) | In 1 condition |
| F13A1coagulation factor XIII A chain | Sometimes (5–29%) | In 2 conditions |
| F13Bcoagulation factor XIII B chain | Sometimes (5–29%) | In 1 condition |
| F9coagulation factor IX | Sometimes (5–29%) | In 1 condition |
| FCGR2CFc gamma receptor IIc (gene/pseudogene) | Sometimes (5–29%) | In 1 condition |
| FERMT3FERM domain containing kindlin 3 | Sometimes (5–29%) | In 1 condition |
| GIMAP5GTPase, IMAP family member 5 | Sometimes (5–29%) | In 1 condition |
| GP1BBglycoprotein Ib platelet subunit beta | Sometimes (5–29%) | In 2 conditions |
| HLA-Bmajor histocompatibility complex, class I, B | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Sometimes (5–29%) | In 1 condition |
| IFNGinterferon gamma | Sometimes (5–29%) | In 1 condition |
| ITGB3integrin subunit beta 3 | Sometimes (5–29%) | In 2 conditions |
| KCNJ5potassium inwardly rectifying channel subfamily J member 5 | Sometimes (5–29%) | In 1 condition |
| LAMA3laminin subunit alpha 3 | Sometimes (5–29%) | In 1 condition |
| MYD88MYD88 innate immune signal transduction adaptor | Sometimes (5–29%) | In 1 condition |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Sometimes (5–29%) | In 1 condition |
| PRF1perforin 1 | Sometimes (5–29%) | In 1 condition |
| SBDSSBDS ribosome maturation factor | Sometimes (5–29%) | In 1 condition |
| SERPINE1serpin family E member 1 | Sometimes (5–29%) | In 1 condition |
| SLC37A4solute carrier family 37 member 4 | Sometimes (5–29%) | In 1 condition |
| TERCtelomerase RNA component | Sometimes (5–29%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Sometimes (5–29%) | In 1 condition |
| TPM4tropomyosin 4 | Sometimes (5–29%) | In 1 condition |
| TRPM7transient receptor potential cation channel subfamily M member 7 | Sometimes (5–29%) | In 1 condition |
| TUBA8tubulin alpha 8 | Sometimes (5–29%) | In 1 condition |
| TUBB1tubulin beta 1 class VI | Sometimes (5–29%) | In 1 condition |
| VKORC1vitamin K epoxide reductase complex subunit 1 | Sometimes (5–29%) | In 1 condition |
| WASWASP actin nucleation promoting factor | Sometimes (5–29%) | In 3 conditions |
| ETV6ETS variant transcription factor 6 | Not recorded | In 1 condition |
| GATA1GATA binding protein 1 | Not recorded | In 2 conditions |
| GBA1glucosylceramidase beta 1 | Not recorded | In 1 condition |
| GP6glycoprotein VI platelet | Not recorded | In 1 condition |
| GP9glycoprotein IX platelet | Not recorded | In 1 condition |
| HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 | Not recorded | In 1 condition |
| MYH9myosin heavy chain 9 | Not recorded | In 1 condition |
| P2RY12purinergic receptor P2Y12 | Not recorded | In 1 condition |
| PLAUplasminogen activator, urokinase | Not recorded | In 1 condition |
| RUNX1RUNX family transcription factor 1 | Not recorded | In 1 condition |
| SLFN14schlafen family member 14 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks