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Gene

HMOX1

heme oxygenase 1

Summary

Cytogenetic location
22q12.3
Coordinates
Chromosome 22: 35,381,096–35,394,207 (GRCh38)
Exons
5 exons across 13.1 kb
Protein
288 amino acids
Also known as
bK286B10, HO-1
MANE Select transcript
ENST00000216117.9NM_002133.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HMOX1 yet. The test sequences your whole genome, so your data includes it all the same.

How HMOX1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 22, with a bracket where HMOX1 sits. HMOX1 and 9 genes near it on chromosome 22, from 34,887,652 to 35,887,651.Chromosome 2222q12.3p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3335 Mb35.2 Mb35.4 Mb35.6 Mb35.8 MbISX: 35,066,136–35,087,392, forward strandISXHMGXB4: 35,257,452–35,295,807, forward strandHMGXB4TOM1: 35,299,275–35,351,740, forward strandTOM1HMOX1: 35,381,096–35,394,207, forward strandHMOX1MCM5: 35,400,076–35,452,656, forward strandMCM5RASD2: 35,539,796–35,554,003, forward strandRASD2MB: 35,606,764–35,637,951, reverse strandMBAPOL6: 35,648,128–35,668,409, forward strandAPOL6APOL5: 35,717,872–35,729,483, forward strandAPOL5RBFOX2: 35,738,736–36,028,824, reverse strandRBFOX2Diagram of HMOX1: 5 exons on the forward strand of chromosome 22Exon 3: 2 known disease-causing sitesExon 1: 35,381,096–35,381,196, 101 basesExon 2: 35,383,106–35,383,226, 121 basesExon 3: 35,386,685–35,387,176, 492 basesExon 4: 35,389,864–35,389,963, 100 basesExon 5: 35,393,468–35,394,207, 740 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 13.1 kb; 867 of those bases code for the protein.

How a genome test reads HMOX1

2

positions in HMOX1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 13.1 kb of HMOX1, introns included, not only the 1.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). HMOX1 gene: heme oxygenase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/hmox1

Vancouver

Dante Labs. HMOX1 gene: heme oxygenase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hmox1

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