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Trait
Widely spaced teeth
Increased spaces (diastemata) between most of the teeth in the same dental arch.
Summary
- Also called
- Wide-spaced teeth, Widely-spaced teeth, Generalised dental spacing, Generalised spacing of teeth, Generalized dental spacing, Generalized spacing of teeth, Multiple diastemata
- Body system
- Abnormality of head or neck
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This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/widely-spaced-teeth.json"
page <- fromJSON(url)
page$trait$nameWidely spaced teethHP:0000687
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Read the genes linked to Widely spaced teeth, and the rest of your genome, with one test.
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Get my Genome Test68 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Cornelia de Lange SyndromeReads 6 of these genesSMC3BRD4HDAC8NIPBLRAD21SMC1AAbout this report →
- Hypodontia and AnodontiaReads 6 of these genesEDALRP6MSX1PAX9WNT10AWNT10BAbout this report →
- Intellectual DisabilityReads 24 of these genesTAF4TBL1XR1TCF4BRD4RPS6KA3ADNPAbout this report →
- Ellis-van Creveld Syndrome and Cranioectodermal DysplasiaReads 4 of these genesIFT43IFT52WDR35IFT122About this report →
Show 64 more reports
- DOORS SyndromeReads 2 of these genesATP6V1B2TBC1D24About this report →
- Familial Isolated Pituitary Adenoma (FIPA / X-LAG)Reads 2 of these genesAIPGPR101About this report →
- Kabuki SyndromeReads 2 of these genesKDM6AKMT2DAbout this report →
- Ectodermal DysplasiasReads 5 of these genesEDAEDARADDWNT10ANECTIN4TP63About this report →
- Syndromic CraniosynostosisReads 5 of these genesIFT43IFT52WDR35FGFR1IFT122About this report →
- Acromelic Frontonasal DysostosisReads 1 of these genesZSWIM6About this report →
- Angelman SyndromeReads 1 of these genesUBE3AAbout this report →
- BAP1 Tumour Predisposition SyndromeReads 1 of these genesBAP1About this report →
- DPH1-Related Developmental Delay with Short StatureReads 1 of these genesDPH1About this report →
- Frontonasal Dysplasia with Alopecia and Genital Anomaly (ALX4)Reads 1 of these genesALX4About this report →
- GM1 Gangliosidosis and Morquio B SyndromeReads 1 of these genesGLB1About this report →
- IFT140-Related CiliopathyReads 1 of these genesIFT140About this report →
- Jaberi-Elahi SyndromeReads 1 of these genesGTPBP2About this report →
- KDM1A-Related Neurodevelopmental DisorderReads 1 of these genesKDM1AAbout this report →
- Labyrinthine Aplasia, Microtia and Microdontia (LAMM)Reads 1 of these genesFGF3About this report →
- MED27-Related Neurodevelopmental DisorderReads 1 of these genesMED27About this report →
- Mowat-Wilson SyndromeReads 1 of these genesZEB2About this report →
- Mucopolysaccharidosis Type II (Hunter Syndrome)Reads 1 of these genesIDSAbout this report →
- Mucopolysaccharidosis Type IVA (Morquio A Syndrome)Reads 1 of these genesGALNSAbout this report →
- Mucopolysaccharidosis Type VII (Sly Syndrome)Reads 1 of these genesGUSBAbout this report →
- Rett Syndrome and MECP2-Related DisordersReads 1 of these genesMECP2About this report →
- Short-Rib Thoracic Dysplasia 7 (WDR35)Reads 1 of these genesWDR35About this report →
- Skraban-Deardorff SyndromeReads 1 of these genesWDR26About this report →
- Snijders Blok-Campeau SyndromeReads 1 of these genesCHD3About this report →
- Spondyloepiphyseal Dysplasia With Congenital Joint DislocationsReads 1 of these genesCHST3About this report →
- TANC2-Related Neurodevelopmental DisorderReads 1 of these genesTANC2About this report →
- Turnpenny-Fry SyndromeReads 1 of these genesPCGF2About this report →
- Hereditary Orofacial CleftingReads 2 of these genesIRF6MSX1About this report →
- Epilepsy (Full Panel)Reads 11 of these genesCDK19PIGASMC1APACS2RNU2-2ATP6V1B2About this report →
- Lysosomal Storage DiseaseReads 6 of these genesARSKGUSBMAN2B1GALNSGLB1IDSAbout this report →
- Enlarged Parietal Foramina (MSX2)Reads 1 of these genesALX4About this report →
- Fibrodysplasia Ossificans ProgressivaReads 1 of these genesACVR1About this report →
- PRR12-Related Neuroocular SyndromeReads 1 of these genesPRR12About this report →
- GPI Anchor Biosynthesis DefectsReads 3 of these genesPIGAPIGLPIGSAbout this report →
- Van der Woude and Popliteal Pterygium Syndromes (IRF6)Reads 1 of these genesIRF6About this report →
- Familial Atrial FibrillationReads 1 of these genesGJA5About this report →
- Noonan SyndromeReads 2 of these genesMAPK1PPP1CBAbout this report →
- Congenital Disorders of GlycosylationReads 4 of these genesPIGASSR4B3GLCTPIGLAbout this report →
- Alpha-Mannosidosis and Other GlycoproteinosesReads 1 of these genesMAN2B1About this report →
- Oculocutaneous AlbinismReads 1 of these genesOCA2About this report →
- Pyruvate Kinase Deficiency and Other Red Cell Enzyme DisordersReads 1 of these genesHK1About this report →
- Retinitis PigmentosaReads 3 of these genesIFT140IFT43HK1About this report →
- Kidney CancerReads 1 of these genesBAP1About this report →
- HyperinsulinismReads 1 of these genesHK1About this report →
- Polycystic Kidney DiseaseReads 1 of these genesIFT140About this report →
- Urinary and Renal System TumourReads 1 of these genesBAP1About this report →
- Hypertrophic CardiomyopathyReads 2 of these genesMAPK1PPP1CBAbout this report →
- Hereditary Hypotrichosis, Woolly Hair and MonilethrixReads 1 of these genesCDH3About this report →
- Amelogenesis ImperfectaReads 1 of these genesDLX3About this report →
- Autosomal Recessive Primary MicrocephalyReads 1 of these genesCDK5RAP2About this report →
- Hereditary Corneal DystrophiesReads 1 of these genesTCF4About this report →
- Pontocerebellar Hypoplasia (TSEN54 and MINPP1)Reads 1 of these genesCLP1About this report →
- Lissencephaly Spectrum DisordersReads 1 of these genesKATNB1About this report →
- Pelizaeus-Merzbacher Disease & Hypomyelinating LeukodystrophiesReads 1 of these genesAIMP2About this report →
- Diabetes MellitusReads 1 of these genesEIF2S3About this report →
- Inherited ThrombocytopeniasReads 1 of these genesCDC42About this report →
- Hereditary Palmoplantar Keratodermas and Pachyonychia CongenitaReads 1 of these genesWNT10AAbout this report →
- Hypogonadotropic HypogonadismReads 1 of these genesFGFR1About this report →
- Female InfertilityReads 1 of these genesTP63About this report →
- Charcot-Marie-Tooth DiseaseReads 1 of these genesHK1About this report →
- Other Inherited LeukodystrophiesReads 1 of these genesAIMP2About this report →
- Inherited Neurodegenerative DisordersReads 2 of these genesAIMP2TBCDAbout this report →
- Hearing Loss and DeafnessReads 1 of these genesTBC1D24About this report →
- Rare Hereditary Peripheral NeuropathiesReads 1 of these genesHK1About this report →
Read the genes linked to Widely spaced teeth, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test129 genes linked to Widely spaced teeth
Changes in these genes cause rare conditions in which Widely spaced teeth is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CDK19cyclin dependent kinase 19 | Always | In 1 condition |
| CDK5RAP2CDK5 regulatory subunit associated protein 2 | Always | In 1 condition |
| DRG1developmentally regulated GTP binding protein 1 | Always | In 1 condition |
| FGF3fibroblast growth factor 3 | Always | In 2 conditions |
| GTPBP2GTP binding protein 2 | Always | In 1 condition |
| IFT140intraflagellar transport 140 | Always | In 2 conditions |
| IFT43intraflagellar transport 43 | Always | In 1 condition |
| IFT52intraflagellar transport 52 | Always | In 1 condition |
| JKAMPJNK1/MAPK8 associated membrane protein | Always | In 1 condition |
| KDM1Alysine demethylase 1A | Always | In 2 conditions |
| KIAA0753KIAA0753 | Always | In 1 condition |
| MED16mediator complex subunit 16 | Always | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Always | In 2 conditions |
| PPFIA3PPFI scaffold protein A3 | Always | In 1 condition |
| RDH11retinol dehydrogenase 11 | Always | In 1 condition |
| SMC3structural maintenance of chromosomes 3 | Always | In 2 conditions |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| TBL1XR1TBL1X/Y related 1 | Always | In 2 conditions |
| TCF4transcription factor 4 | Always | In 1 condition |
| WDR35WD repeat domain 35 | Always | In 1 condition |
| BRD4bromodomain containing 4 | Very often (80–99%) | In 1 condition |
| HDAC4histone deacetylase 4 | Very often (80–99%) | In 1 condition |
| HDAC8histone deacetylase 8 | Very often (80–99%) | In 2 conditions |
| LARP7La ribonucleoprotein 7, transcriptional regulator | Very often (80–99%) | In 2 conditions |
| MAU2MAU2 sister chromatid cohesion factor | Very often (80–99%) | In 2 conditions |
| NIPBLNIPBL cohesin loading factor | Very often (80–99%) | In 2 conditions |
| RAD21RAD21 cohesin complex component | Very often (80–99%) | In 1 condition |
| RPS6KA3ribosomal protein S6 kinase A3 | Very often (80–99%) | In 2 conditions |
| SMC1Astructural maintenance of chromosomes 1A | Very often (80–99%) | In 2 conditions |
| SSR4signal sequence receptor subunit 4 | Very often (80–99%) | In 2 conditions |
| WDR26WD repeat domain 26 | Very often (80–99%) | In 2 conditions |
| ADNPactivity dependent neuroprotector homeobox | Often (30–79%) | In 1 condition |
| AFF3ALF transcription elongation factor 3 | Often (30–79%) | In 1 condition |
| AHDC1AT-hook DNA binding motif containing 1 | Often (30–79%) | In 1 condition |
| AIMP2aminoacyl tRNA synthetase complex interacting multifunctional protein 2 | Often (30–79%) | In 1 condition |
| AIPAHR interacting HSP90 co-chaperone | Often (30–79%) | In 1 condition |
| ALX4ALX homeobox 4 | Often (30–79%) | In 1 condition |
| ARSKarylsulfatase family member K | Often (30–79%) | In 1 condition |
| B3GLCTbeta 3-glucosyltransferase | Often (30–79%) | In 2 conditions |
| CDH3cadherin 3 | Often (30–79%) | In 2 conditions |
Show 89 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| CERT1ceramide transporter 1 | Often (30–79%) | In 1 condition |
| CLP1cleavage factor polyribonucleotide kinase subunit 1 | Often (30–79%) | In 1 condition |
| DLX3distal-less homeobox 3 | Often (30–79%) | In 2 conditions |
| DYRK1Adual specificity tyrosine phosphorylation regulated kinase 1A | Often (30–79%) | In 2 conditions |
| EDAectodysplasin A | Often (30–79%) | In 1 condition |
| EDARADDEDAR associated via death domain | Often (30–79%) | In 1 condition |
| FGF10fibroblast growth factor 10 | Often (30–79%) | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Often (30–79%) | In 1 condition |
| GPR101G protein-coupled receptor 101 | Often (30–79%) | In 2 conditions |
| GREM2gremlin 2, DAN family BMP antagonist | Often (30–79%) | In 1 condition |
| GUSBglucuronidase beta | Often (30–79%) | In 1 condition |
| IRF6interferon regulatory factor 6 | Often (30–79%) | In 1 condition |
| KANSL1KAT8 regulatory NSL complex subunit 1 | Often (30–79%) | In 1 condition |
| KDM6Alysine demethylase 6A | Often (30–79%) | In 2 conditions |
| KMT2Dlysine methyltransferase 2D | Often (30–79%) | In 2 conditions |
| LRP6LDL receptor related protein 6 | Often (30–79%) | In 1 condition |
| MBD5methyl-CpG binding domain protein 5 | Often (30–79%) | In 1 condition |
| MSX1msh homeobox 1 | Often (30–79%) | In 1 condition |
| NONOnon-POU domain containing octamer binding | Often (30–79%) | In 2 conditions |
| OCA2OCA2 melanosomal transmembrane protein | Often (30–79%) | In 1 condition |
| PACS2phosphofurin acidic cluster sorting protein 2 | Often (30–79%) | In 1 condition |
| PAX9paired box 9 | Often (30–79%) | In 1 condition |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Often (30–79%) | In 1 condition |
| PRKD1protein kinase D1 | Often (30–79%) | In 1 condition |
| PRR12proline rich 12 | Often (30–79%) | In 1 condition |
| PTPRFprotein tyrosine phosphatase receptor type F | Often (30–79%) | In 1 condition |
| RLIMring finger protein, LIM domain interacting | Often (30–79%) | In 1 condition |
| RNU2-2RNA, U2 small nuclear 2 | Often (30–79%) | In 1 condition |
| SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 | Often (30–79%) | In 2 conditions |
| SUMO1small ubiquitin like modifier 1 | Often (30–79%) | In 1 condition |
| TBCDtubulin folding cofactor D | Often (30–79%) | In 2 conditions |
| TGFAtransforming growth factor alpha | Often (30–79%) | In 1 condition |
| UBE3Aubiquitin protein ligase E3A | Often (30–79%) | In 4 conditions |
| WNT10AWnt family member 10A | Often (30–79%) | In 1 condition |
| WNT10BWnt family member 10B | Often (30–79%) | In 1 condition |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Sometimes (5–29%) | In 1 condition |
| ATXN7L3ataxin 7 like 3 | Sometimes (5–29%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Sometimes (5–29%) | In 1 condition |
| BCAS3BCAS3 microtubule associated cell migration factor | Sometimes (5–29%) | In 1 condition |
| CAMK2Bcalcium/calmodulin dependent protein kinase II beta | Sometimes (5–29%) | In 1 condition |
| CDC42cell division cycle 42 | Sometimes (5–29%) | In 2 conditions |
| CDC42BPBCDC42 binding protein kinase beta | Sometimes (5–29%) | In 1 condition |
| CEP295centrosomal protein 295 | Sometimes (5–29%) | In 1 condition |
| DPH1diphthamide biosynthesis 1 | Sometimes (5–29%) | In 1 condition |
| DPH2diphthamide biosynthesis 2 | Sometimes (5–29%) | In 1 condition |
| H4C5H4 clustered histone 5 | Sometimes (5–29%) | In 1 condition |
| HK1hexokinase 1 | Sometimes (5–29%) | In 1 condition |
| KATNB1katanin regulatory subunit B1 | Sometimes (5–29%) | In 1 condition |
| LMBRD2LMBR1 domain containing 2 | Sometimes (5–29%) | In 1 condition |
| MAN2B1mannosidase alpha class 2B member 1 | Sometimes (5–29%) | In 2 conditions |
| MAPK1mitogen-activated protein kinase 1 | Sometimes (5–29%) | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Sometimes (5–29%) | In 1 condition |
| MED12mediator complex subunit 12 | Sometimes (5–29%) | In 1 condition |
| MED13Lmediator complex subunit 13L | Sometimes (5–29%) | In 1 condition |
| MED27mediator complex subunit 27 | Sometimes (5–29%) | In 1 condition |
| NAA20N-alpha-acetyltransferase 20, NatB catalytic subunit | Sometimes (5–29%) | In 1 condition |
| NARS1asparaginyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| NDST1N-deacetylase and N-sulfotransferase 1 | Sometimes (5–29%) | In 1 condition |
| PIGSphosphatidylinositol glycan anchor biosynthesis class S | Sometimes (5–29%) | In 1 condition |
| PPP1CBprotein phosphatase 1 catalytic subunit beta | Sometimes (5–29%) | In 1 condition |
| RHOBTB2Rho related BTB domain containing 2 | Sometimes (5–29%) | In 1 condition |
| SATB1SATB homeobox 1 | Sometimes (5–29%) | In 1 condition |
| SEPHS1selenophosphate synthetase 1 | Sometimes (5–29%) | In 1 condition |
| SETD1ASET domain containing 1A, histone lysine methyltransferase | Sometimes (5–29%) | In 1 condition |
| SHANK3SH3 and multiple ankyrin repeat domains 3 | Sometimes (5–29%) | In 1 condition |
| TBC1D24TBC1 domain family member 24 | Sometimes (5–29%) | In 1 condition |
| TBX4T-box transcription factor 4 | Sometimes (5–29%) | In 1 condition |
| TTI1TELO2 interacting protein 1 | Sometimes (5–29%) | In 1 condition |
| TWIST2twist family bHLH transcription factor 2 | Sometimes (5–29%) | In 1 condition |
| ZNF526zinc finger protein 526 | Sometimes (5–29%) | In 1 condition |
| CHD3chromodomain helicase DNA binding protein 3 | Rarely (1–4%) | In 1 condition |
| CNTNAP2contactin associated protein 2 | Rarely (1–4%) | In 1 condition |
| GJA5gap junction protein alpha 5 | Rarely (1–4%) | In 1 condition |
| GJA8gap junction protein alpha 8 | Rarely (1–4%) | In 1 condition |
| ACVR1activin A receptor type 1 | Not recorded | In 1 condition |
| CCDC47coiled-coil domain containing 47 | Not recorded | In 1 condition |
| CHST3carbohydrate sulfotransferase 3 | Not recorded | In 1 condition |
| EIF2S3eukaryotic translation initiation factor 2 subunit gamma | Not recorded | In 1 condition |
| GALNSgalactosamine (N-acetyl)-6-sulfatase | Not recorded | In 1 condition |
| GLB1galactosidase beta 1 | Not recorded | In 1 condition |
| IDSiduronate 2-sulfatase | Not recorded | In 1 condition |
| IFT122intraflagellar transport 122 | Not recorded | In 1 condition |
| LTBP3latent transforming growth factor beta binding protein 3 | Not recorded | In 1 condition |
| NECTIN4nectin cell adhesion molecule 4 | Not recorded | In 1 condition |
| PCGF2polycomb group ring finger 2 | Not recorded | In 1 condition |
| TANC2tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | Not recorded | In 1 condition |
| TP63tumor protein p63 | Not recorded | In 1 condition |
| ZEB2zinc finger E-box binding homeobox 2 | Not recorded | In 1 condition |
| ZSWIM6zinc finger SWIM-type containing 6 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.19-9814e911.
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