Skip to content
Use your HSA or FSA funds

Gene

TTI1

TELO2 interacting protein 1

Summary

Cytogenetic location
20q11.23
Coordinates
Chromosome 20: 37,983,021–38,033,456 (GRCh38)
Exons
8 exons across 50.4 kb
Protein
1,089 amino acids
Also known as
smg-10
Previous symbols
KIAA0406
MANE Select transcript
ENST00000373447.8NM_001303457.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TTI1 yet. The test sequences your whole genome, so your data includes it all the same.

How TTI1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 20, with a bracket where TTI1 sits. TTI1 and 10 genes near it on chromosome 20, from 37,508,239 to 38,508,238.Chromosome 2020q11.23p13p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12q13.11q13.12q13.13q13.2q13.31q13.32q13.3337.6 Mb37.8 Mb38 Mb38.2 Mb38.4 MbBLCAP: 37,492,472–37,528,100, reverse strandBLCAPNNAT: 37,521,201–37,523,690, forward strandNNATCTNNBL1: 37,693,949–37,872,129, forward strandCTNNBL1VSTM2L: 37,902,987–37,945,354, forward strandVSTM2LTTI1: 37,983,021–38,033,456, reverse strandTTI1RPRD1B: 38,033,514–38,127,780, forward strandRPRD1BTGM2: 38,127,385–38,168,463, reverse strandTGM2KIAA1755: 38,210,503–38,261,039, reverse strandKIAA1755BPI: 38,260,141–38,337,505, forward strandBPILBP: 38,346,076–38,378,131, forward strandLBPRALGAPB: 38,472,813–38,579,009, forward strandRALGAPBDiagram of TTI1: 8 exons on the reverse strand of chromosome 20Exon 2: 3 known disease-causing sitesExon 8: 37,983,021–37,983,639, 619 basesExon 7: 37,996,375–37,996,462, 88 basesExon 6: 37,996,749–37,996,953, 205 basesExon 5: 37,999,188–37,999,328, 141 basesExon 4: 38,002,628–38,002,776, 149 basesExon 3: 38,006,197–38,006,397, 201 basesExon 2: 38,011,515–38,013,857, 2,343 basesExon 1: 38,033,404–38,033,456, 53 bases864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.8 kb of the gene's 50.4 kb; 3,270 of those bases code for the protein.

How a genome test reads TTI1

3

positions in TTI1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 50.4 kb of TTI1, introns included, not only the 3.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TTI1 gene: TELO2 interacting protein 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/tti1

Vancouver

Dante Labs. TTI1 gene: TELO2 interacting protein 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tti1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test