Skip to content
Use your HSA or FSA funds

Gene

TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

Summary

Cytogenetic location
17q23.2-q23.3
Coordinates
Chromosome 17: 62,966,235–63,427,703 (GRCh38)
Exons
28 exons across 461.5 kb
Protein
2,074 amino acids
Also known as
DKFZP564D166, FLJ10215, FLJ11824, KIAA1148, KIAA1636, rols, ROLSA
MANE Select transcript
ENST00000689528.1NM_001394998.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TANC2 yet. The test sequences your whole genome, so your data includes it all the same.

How TANC2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where TANC2 sits. TANC2 and 21 genes near it on chromosome 17, from 62,504,766 to 63,889,172.Chromosome 1717q23.2-q23.3p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.362.6 Mb62.8 Mb63 Mb63.2 Mb63.4 Mb63.6 Mb63.8 MbTLK2: 62,458,658–62,615,481, forward strandTLK2MRC2: 62,627,417–62,693,597, forward strandMRC2MARCHF10: 62,701,314–62,808,344, reverse strandMARCHF10TANC2: 62,966,235–63,427,703, forward strandTANC2CYB561: 63,432,298–63,447,108, reverse strandCYB561ACE: 63,477,058–63,498,380, forward strandACE: 63,484,823–63,521,848, forward strandKCNH6: 63,523,310–63,548,987, forward strandKCNH6DCAF7: 63,550,222–63,594,286, forward strandDCAF7: 63,550,603–63,608,347, forward strandTACO1: 63,600,879–63,612,023, forward strandTACO1MAP3K3: 63,622,379–63,696,310, forward strandMAP3K3STRADA: 63,682,336–63,742,005, reverse strandSTRADALIMD2: 63,695,883–63,701,183, reverse strandLIMD2: 63,702,845–63,752,097, reverse strandCCDC47: 63,745,250–63,776,351, reverse strandCCDC47DDX42: 63,773,603–63,820,451, forward strandDDX42FTSJ3: 63,819,113–63,830,012, reverse strandFTSJ3PSMC5: 63,827,082–63,832,244, forward strandPSMC5SMARCD2: 63,832,078–63,843,065, reverse strandCSH2: 63,872,007–63,873,769, reverse strandCSH2GH2: 63,880,205–63,881,970, reverse strandGH2Diagram of TANC2: 28 exons on the forward strand of chromosome 17Exon 7: 1 known disease-causing siteExon 9: 3 known disease-causing sitesExon 13: 1 known disease-causing siteExon 14: 3 known disease-causing sitesExon 15: 1 known disease-causing siteExon 16: 1 known disease-causing siteExon 17: 1 known disease-causing siteExon 19: 1 known disease-causing siteExon 20: 1 known disease-causing siteExon 25: 1 known disease-causing siteExon 26: 1 known disease-causing siteExon 28: 1 known disease-causing siteExon 1: 62,966,235–62,966,749, 515 basesExon 2: 63,009,537–63,009,626, 90 basesExon 3: 63,073,943–63,074,014, 72 basesExon 4: 63,099,175–63,099,357, 183 basesExon 5: 63,151,270–63,151,380, 111 basesExon 6: 63,193,991–63,194,139, 149 basesExon 7: 63,200,771–63,200,957, 187 basesExon 8: 63,237,814–63,238,077, 264 basesExon 9: 63,267,748–63,267,873, 126 basesExon 10: 63,314,388–63,314,669, 282 basesExon 11: 63,318,957–63,319,090, 134 basesExon 12: 63,340,101–63,340,332, 232 basesExon 13: 63,351,250–63,351,416, 167 basesExon 14: 63,354,783–63,355,390, 608 basesExon 15: 63,379,718–63,379,826, 109 basesExon 16: 63,388,635–63,388,757, 123 basesExon 17: 63,389,308–63,389,544, 237 basesExon 18: 63,395,743–63,395,928, 186 basesExon 19: 63,398,821–63,398,914, 94 basesExon 20: 63,405,122–63,405,255, 134 basesExon 21: 63,406,154–63,406,277, 124 basesExon 22: 63,411,511–63,411,686, 176 basesExon 23: 63,411,998–63,412,130, 133 basesExon 24: 63,412,680–63,412,709, 30 basesExon 25: 63,413,543–63,413,634, 92 basesExon 26: 63,415,528–63,415,674, 147 basesExon 27: 63,418,307–63,418,407, 101 basesExon 28: 63,419,999–63,427,703, 7,705 bases11020285′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 12.5 kb of the gene's 461.5 kb; 6,225 of those bases code for the protein.

How a genome test reads TANC2

22

positions in TANC2 where ClinVar classes a change as pathogenic or likely pathogenic

2 of them (9.1%) fall in regions short reads find hard.

  • Segmental duplications (2 sites)Copies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy.

A whole genome covers all 461.5 kb of TANC2, introns included, not only the 12.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TANC2 gene: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/tanc2

Vancouver

Dante Labs. TANC2 gene: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tanc2

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test