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Gene

NARS1

asparaginyl-tRNA synthetase 1

Summary

Cytogenetic location
18q21.31
Coordinates
Chromosome 18: 57,600,656–57,621,836 (GRCh38)
Exons
14 exons across 21.2 kb
Protein
548 amino acids
Also known as
AsnRS
Previous symbols
NARS
MANE Select transcript
ENST00000256854.10NM_004539.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NARS1 yet. The test sequences your whole genome, so your data includes it all the same.

How NARS1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 18, with a bracket where NARS1 sits. NARS1 and 6 genes near it on chromosome 18, from 57,111,246 to 58,111,245.Chromosome 1818q21.31p11.32p11.31p11.23p11.22p11.21p11.1q11.1q11.2q12.1q12.2q12.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q2357.2 Mb57.4 Mb57.6 Mb57.8 Mb58 MbBOD1L2: 57,147,087–57,150,410, forward strandBOD1L2ST8SIA3: 57,352,430–57,371,731, forward strandST8SIA3ONECUT2: 57,435,374–57,491,298, forward strandONECUT2FECH: 57,544,377–57,586,942, reverse strandFECHNARS1: 57,600,656–57,621,836, reverse strandNARS1ATP8B1: 57,646,426–57,803,560, reverse strandATP8B1NEDD4L: 58,043,980–58,401,540, forward strandNEDD4LDiagram of NARS1: 14 exons on the reverse strand of chromosome 18Exon 14: 3 known disease-causing sitesExon 13: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 11: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 9: 3 known disease-causing sitesExon 8: 2 known disease-causing sitesExon 5: 1 known disease-causing siteExon 4: 2 known disease-causing sitesExon 3: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 14: 57,600,656–57,601,783, 1,128 basesExon 13: 57,602,355–57,602,486, 132 basesExon 12: 57,602,812–57,602,943, 132 basesExon 11: 57,605,857–57,605,970, 114 basesExon 10: 57,606,616–57,606,751, 136 basesExon 9: 57,607,134–57,607,333, 200 basesExon 8: 57,607,444–57,607,665, 222 basesExon 7: 57,609,357–57,609,443, 87 basesExon 6: 57,611,637–57,611,707, 71 basesExon 5: 57,613,602–57,613,680, 79 basesExon 4: 57,615,641–57,615,730, 90 basesExon 3: 57,615,817–57,615,975, 159 basesExon 2: 57,620,569–57,620,651, 83 basesExon 1: 57,621,708–57,621,836, 129 bases141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.8 kb of the gene's 21.2 kb; 1,647 of those bases code for the protein.

How a genome test reads NARS1

18

positions in NARS1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 21.2 kb of NARS1, introns included, not only the 2.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NARS1 gene: asparaginyl-tRNA synthetase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/nars1

Vancouver

Dante Labs. NARS1 gene: asparaginyl-tRNA synthetase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nars1

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