Trait
Psychosis
A condition characterized by changes in personality and thought patterns, often accompanied by hallucinations and delusional beliefs, is known as psychosis.
Summary
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
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Get my Genome Test147 genes linked to Psychosis
Changes in these genes cause rare conditions in which Psychosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| LRRC7leucine rich repeat containing 7 | Always | In 1 condition |
| MMADHCmetabolism of cobalamin associated D | Always | In 1 condition |
| NOTCH3notch receptor 3 | Always | In 1 condition |
| RFC4replication factor C subunit 4 | Always | In 1 condition |
| TBC1D7TBC1 domain family member 7 | Always | In 1 condition |
| TRRAPtransformation/transcription domain associated protein | Always | In 1 condition |
| UNC13Aunc-13 homolog A | Always | In 1 condition |
| WFS1wolframin ER transmembrane glycoprotein | Very often (80–99%) | In 1 condition |
| CMPK2cytidine/uridine monophosphate kinase 2 | Often (30–79%) | In 1 condition |
| DNMT1DNA methyltransferase 1 | Often (30–79%) | In 1 condition |
| H4C3H4 clustered histone 3 | Often (30–79%) | In 1 condition |
| JAM2junctional adhesion molecule 2 | Often (30–79%) | In 2 conditions |
| MAGEL2MAGE family member L2 | Often (30–79%) | In 5 conditions |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Often (30–79%) | In 1 condition |
| MT-CO2mitochondrially encoded cytochrome c oxidase II | Often (30–79%) | In 1 condition |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Often (30–79%) | In 1 condition |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Often (30–79%) | In 1 condition |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Often (30–79%) | In 1 condition |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Often (30–79%) | In 1 condition |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Often (30–79%) | In 1 condition |
| MT-TFmitochondrially encoded tRNA-Phe (UUU/C) | Often (30–79%) | In 1 condition |
| MT-THmitochondrially encoded tRNA-His (CAU/C) | Often (30–79%) | In 1 condition |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Often (30–79%) | In 1 condition |
| MT-TQmitochondrially encoded tRNA-Gln (CAA/G) | Often (30–79%) | In 1 condition |
| MT-TS1mitochondrially encoded tRNA-Ser (UCN) 1 | Often (30–79%) | In 1 condition |
| MT-TS2mitochondrially encoded tRNA-Ser (AGU/C) 2 | Often (30–79%) | In 1 condition |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Often (30–79%) | In 1 condition |
| MYORGmyogenesis regulating glycosidase | Often (30–79%) | In 3 conditions |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Often (30–79%) | In 3 conditions |
| NDNnecdin, MAGE family member | Often (30–79%) | In 3 conditions |
| NDPnorrin cystine knot growth factor NDP | Often (30–79%) | In 2 conditions |
| OCA2OCA2 melanosomal transmembrane protein | Often (30–79%) | In 3 conditions |
| PDGFBplatelet derived growth factor subunit B | Often (30–79%) | In 3 conditions |
| PDGFRBplatelet derived growth factor receptor beta | Often (30–79%) | In 2 conditions |
| RRP12ribosomal RNA processing 12 homolog | Often (30–79%) | In 1 condition |
| SLC20A2solute carrier family 20 member 2 | Often (30–79%) | In 2 conditions |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Often (30–79%) | In 3 conditions |
| TPM2tropomyosin 2 | Often (30–79%) | In 1 condition |
| WARS2tryptophanyl tRNA synthetase 2, mitochondrial | Often (30–79%) | In 1 condition |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Often (30–79%) | In 2 conditions |
Show 107 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| AARS2alanyl-tRNA synthetase 2, mitochondrial | Sometimes (5–29%) | In 1 condition |
| ACADSacyl-CoA dehydrogenase short chain | Sometimes (5–29%) | In 1 condition |
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Sometimes (5–29%) | In 1 condition |
| ASLargininosuccinate lyase | Sometimes (5–29%) | In 1 condition |
| ATP7BATPase copper transporting beta | Sometimes (5–29%) | In 1 condition |
| ATXN7ataxin 7 | Sometimes (5–29%) | In 1 condition |
| BRD4bromodomain containing 4 | Sometimes (5–29%) | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Sometimes (5–29%) | In 2 conditions |
| CBScystathionine beta-synthase | Sometimes (5–29%) | In 1 condition |
| CHD2chromodomain helicase DNA binding protein 2 | Sometimes (5–29%) | In 1 condition |
| CHD8chromodomain helicase DNA binding protein 8 | Sometimes (5–29%) | In 1 condition |
| CHMP2Bcharged multivesicular body protein 2B | Sometimes (5–29%) | In 1 condition |
| CLTRNcollectrin, amino acid transport regulator | Sometimes (5–29%) | In 1 condition |
| CPOXcoproporphyrinogen oxidase | Sometimes (5–29%) | In 1 condition |
| CUX2cut like homeobox 2 | Sometimes (5–29%) | In 1 condition |
| DCAF17DDB1 and CUL4 associated factor 17 | Sometimes (5–29%) | In 2 conditions |
| DNM1dynamin 1 | Sometimes (5–29%) | In 1 condition |
| EHMT1euchromatic histone lysine methyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| GABRB3gamma-aminobutyric acid type A receptor subunit beta3 | Sometimes (5–29%) | In 1 condition |
| GCLCglutamate-cysteine ligase catalytic subunit | Sometimes (5–29%) | In 1 condition |
| GRNgranulin precursor | Sometimes (5–29%) | In 1 condition |
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Sometimes (5–29%) | In 1 condition |
| IRAK1interleukin 1 receptor associated kinase 1 | Sometimes (5–29%) | In 1 condition |
| JARID2jumonji and AT-rich interaction domain containing 2 | Sometimes (5–29%) | In 1 condition |
| KCNN2potassium calcium-activated channel subfamily N member 2 | Sometimes (5–29%) | In 1 condition |
| KCNT1potassium sodium-activated channel subfamily T member 1 | Sometimes (5–29%) | In 1 condition |
| KDM6Blysine demethylase 6B | Sometimes (5–29%) | In 1 condition |
| MAPK10mitogen-activated protein kinase 10 | Sometimes (5–29%) | In 1 condition |
| MAPTmicrotubule associated protein tau | Sometimes (5–29%) | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Sometimes (5–29%) | In 1 condition |
| MED12mediator complex subunit 12 | Sometimes (5–29%) | In 2 conditions |
| MKRN3makorin ring finger protein 3 | Sometimes (5–29%) | In 1 condition |
| MTHFRmethylenetetrahydrofolate reductase | Sometimes (5–29%) | In 1 condition |
| NIT1nitrilase 1 | Sometimes (5–29%) | In 1 condition |
| NPAP1nuclear pore associated protein 1 | Sometimes (5–29%) | In 1 condition |
| PAK3p21 (RAC1) activated kinase 3 | Sometimes (5–29%) | In 1 condition |
| PIDD1p53-induced death domain protein 1 | Sometimes (5–29%) | In 1 condition |
| PRORPprotein only RNase P catalytic subunit | Sometimes (5–29%) | In 1 condition |
| PSEN1presenilin 1 | Sometimes (5–29%) | In 1 condition |
| PUS3pseudouridine synthase 3 | Sometimes (5–29%) | In 1 condition |
| PWAR1Prader Willi/Angelman region RNA 1 | Sometimes (5–29%) | In 1 condition |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Sometimes (5–29%) | In 1 condition |
| RPS6KA3ribosomal protein S6 kinase A3 | Sometimes (5–29%) | In 1 condition |
| SAT1spermidine/spermine N1-acetyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Sometimes (5–29%) | In 1 condition |
| SIM1SIM bHLH transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| SLC25A13solute carrier family 25 member 13 | Sometimes (5–29%) | In 1 condition |
| SLC6A19solute carrier family 6 member 19 | Sometimes (5–29%) | In 2 conditions |
| SMAD4SMAD family member 4 | Sometimes (5–29%) | In 1 condition |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Sometimes (5–29%) | In 1 condition |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Sometimes (5–29%) | In 1 condition |
| SOBPsine oculis binding protein homolog | Sometimes (5–29%) | In 1 condition |
| SPARTspartin | Sometimes (5–29%) | In 1 condition |
| SPG11SPG11 vesicle trafficking associated, spatacsin | Sometimes (5–29%) | In 1 condition |
| SPP1secreted phosphoprotein 1 | Sometimes (5–29%) | In 1 condition |
| SQSTM1sequestosome 1 | Sometimes (5–29%) | In 1 condition |
| SRCAPSnf2 related CREBBP activator protein | Sometimes (5–29%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Sometimes (5–29%) | In 1 condition |
| TMEM106Btransmembrane protein 106B | Sometimes (5–29%) | In 2 conditions |
| TREM2triggering receptor expressed on myeloid cells 2 | Sometimes (5–29%) | In 1 condition |
| TREX1three prime repair exonuclease 1 | Sometimes (5–29%) | In 2 conditions |
| UPF3BUPF3B regulator of nonsense mediated mRNA decay | Sometimes (5–29%) | In 1 condition |
| VCPvalosin containing protein | Sometimes (5–29%) | In 1 condition |
| ZDHHC9zDHHC palmitoyltransferase 9 | Sometimes (5–29%) | In 1 condition |
| ZMYM2zinc finger MYM-type containing 2 | Sometimes (5–29%) | In 1 condition |
| ATRXATRX chromatin remodeler | Rarely (1–4%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Rarely (1–4%) | In 1 condition |
| CDH23cadherin related 23 | Rarely (1–4%) | In 1 condition |
| CTSHcathepsin H | Rarely (1–4%) | In 1 condition |
| EIF3Feukaryotic translation initiation factor 3 subunit F | Rarely (1–4%) | In 1 condition |
| FTLferritin light chain | Rarely (1–4%) | In 1 condition |
| HCRThypocretin neuropeptide precursor | Rarely (1–4%) | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Rarely (1–4%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Rarely (1–4%) | In 1 condition |
| MMACHCmetabolism of cobalamin associated C | Rarely (1–4%) | In 1 condition |
| MOGmyelin oligodendrocyte glycoprotein | Rarely (1–4%) | In 1 condition |
| NR3C1nuclear receptor subfamily 3 group C member 1 | Rarely (1–4%) | In 1 condition |
| P2RY11purinergic receptor P2Y11 | Rarely (1–4%) | In 1 condition |
| PANK2pantothenate kinase 2 | Rarely (1–4%) | In 1 condition |
| PCDH19protocadherin 19 | Rarely (1–4%) | In 2 conditions |
| TNFSF4TNF superfamily member 4 | Rarely (1–4%) | In 1 condition |
| TP53tumor protein p53 | Rarely (1–4%) | In 1 condition |
| USP48ubiquitin specific peptidase 48 | Rarely (1–4%) | In 1 condition |
| USP8ubiquitin specific peptidase 8 | Rarely (1–4%) | In 1 condition |
| ZNF365zinc finger protein 365 | Rarely (1–4%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Not recorded | In 1 condition |
| ALDH5A1aldehyde dehydrogenase 5 family member A1 | Not recorded | In 1 condition |
| CLN3CLN3 lysosomal/endosomal transmembrane protein, battenin | Not recorded | In 1 condition |
| DNASE1deoxyribonuclease 1 | Not recorded | In 1 condition |
| EPM2AEPM2A glucan phosphatase, laforin | Not recorded | In 1 condition |
| FCGR2AFc gamma receptor IIa | Not recorded | In 1 condition |
| FCGR2BFc gamma receptor IIb | Not recorded | In 1 condition |
| GNASGNAS complex locus | Not recorded | In 1 condition |
| ITM2Bintegral membrane protein 2B | Not recorded | In 1 condition |
| NPC1NPC intracellular cholesterol transporter 1 | Not recorded | In 1 condition |
| NPC2NPC intracellular cholesterol transporter 2 | Not recorded | In 1 condition |
| PAHphenylalanine hydroxylase | Not recorded | In 1 condition |
| PDE11Aphosphodiesterase 11A | Not recorded | In 1 condition |
| PPOXprotoporphyrinogen oxidase | Not recorded | In 1 condition |
| PRDM8PR/SET domain 8 | Not recorded | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Not recorded | In 1 condition |
| PRNPprion protein (Kanno blood group) | Not recorded | In 1 condition |
| SLC12A6solute carrier family 12 member 6 | Not recorded | In 1 condition |
| TTC19tetratricopeptide repeat domain 19 | Not recorded | In 1 condition |
| TWNKtwinkle mtDNA helicase | Not recorded | In 1 condition |
| VPS13Avacuolar protein sorting 13 homolog A | Not recorded | In 1 condition |
| ZFYVE26zinc finger FYVE-type containing 26 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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