Gene
FCGR2A
Fc gamma receptor IIa
- HGNC 3616↗(opens in a new tab)
- Ensembl gene ENSG00000143226↗(opens in a new tab)
- NCBI Gene 2212↗(opens in a new tab)
Summary
- Cytogenetic location
- 1q23.3
- Coordinates
- Chromosome 1: 161,505,457–161,519,829 (GRCh38)
- Exons
- 7 exons across 14.4 kb
- Protein
- 317 amino acids
- Also known as
- CD32, CD32A, IGFR2, CDw32, Fc-gamma-RIIa, FcgammaRIIa
- Previous symbols
- FCG2, FCGR2A1, FCGR2
- MANE Select transcript
- ENST00000271450.12NM_001136219.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How FCGR2A is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.6 kb of the gene's 14.4 kb; 954 of those bases code for the protein.
Traits linked to FCGR2A
The Human Phenotype Ontology lists these as features of the rare conditions FCGR2A can cause. Each trait's page lists the other genes linked to it.
Abnormality of the digestive system
- Inability to properly digest food due to lack of pancreatic digestive enzymes
- Diarrhea
- Fat in feces
- Pancreatic inflammation
- Enlarged liver
- Ileus
- Scar tissue replaces healthy tissue in the liver
- Biliary cirrhosis
Show 2 more traits
Abnormality of the respiratory system
- Permanent enlargement of the airways of the lungs
- Decreased forced expiratory flow 25-75%
- Reduced forced expiratory volume in one second
- Coughing up blood
- Reduced forced vital capacity
- Chronic lung disease
- Hyperpolarized transepithelial nasal potential difference
- Inflammation of tissues lining lungs and chest
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). FCGR2A gene: Fc gamma receptor IIa. Retrieved 16 October 2026, from https://dantelabs.com/genes/fcgr2a
Dante Labs. FCGR2A gene: Fc gamma receptor IIa [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fcgr2a
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