Gene
RRP12
ribosomal RNA processing 12 homolog
- HGNC 29100(opens in a new tab)
- Ensembl gene ENSG00000052749(opens in a new tab)
- NCBI Gene 23223(opens in a new tab)
Summary
- Cytogenetic location
- 10q24.1
- Coordinates
- Chromosome 10: 97,356,701–97,401,340 (GRCh38)
- Exons
- 34 exons across 44.6 kb
- Protein
- 1,297 amino acids
- Previous symbols
- KIAA0690
- MANE Select transcript
- ENST00000370992.9NM_015179.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How RRP12 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.4 kb of the gene's 44.6 kb; 3,894 of those bases code for the protein.
Traits linked to RRP12
The Human Phenotype Ontology lists these as features of the rare conditions RRP12 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Can't control feelings
- Difficulty articulating speech
- Diffuse leukoencephalopathy
- Generalized brain degeneration
- Generalized-onset seizure
- Headache
- Impaired executive functioning
- Incoordination
Show 31 more traits
- Leukoencephalopathy
- Loss of ability to walk
- Loss of articulate speech
- Memory impairment
- Seizure affecting one half of brain
- Stuttering
- Tetraparesis
- Thalamic calcification
- Anxiety
- Bilateral basal ganglia lesions
- Choreoathetosis
- Dementia
- Dystonia
- Epilepsy
- Mental deterioration
- Personality changes
- Psychosis
- Slow movements
- Tremor
- Worsening neurological symptoms
- Abnormal pyramidal sign
- Ataxia
- Bipolar disorder
- Chorea
- Clumsiness
- Disorder of involuntary muscle movements
- Involuntary movements
- Parkinsonism
- Poor concentration
- Slurred speech
- Unsteady walk
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). RRP12 gene: ribosomal RNA processing 12 homolog. Retrieved 17 October 2026, from https://dantelabs.com/genes/rrp12
Dante Labs. RRP12 gene: ribosomal RNA processing 12 homolog [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rrp12
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