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Gene

KCNN2

potassium calcium-activated channel subfamily N member 2

Summary

Cytogenetic location
5q22.3
Coordinates
Chromosome 5: 114,362,070–114,496,496 (GRCh38)
Exons
8 exons across 134.4 kb
Protein
791 amino acids
Also known as
KCa2.2, hSK2
MANE Select transcript
ENST00000673685.1NM_021614.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KCNN2 yet. The test sequences your whole genome, so your data includes it all the same.

How KCNN2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 5, with a bracket where KCNN2 sits. KCNN2 and 0 genes near it on chromosome 5, from 113,929,283 to 114,929,282.Chromosome 55q22.3p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.3114 Mb114.2 Mb114.4 Mb114.6 Mb114.8 MbKCNN2: 114,362,070–114,496,496, forward strandKCNN2Diagram of KCNN2: 8 exons on the forward strand of chromosome 5Exon 1: 1 known disease-causing siteExon 3: 2 known disease-causing sitesExon 4: 3 known disease-causing sitesExon 5: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 1: 114,362,070–114,363,261, 1,192 basesExon 2: 114,363,906–114,364,001, 96 basesExon 3: 114,404,438–114,404,856, 419 basesExon 4: 114,463,049–114,463,190, 142 basesExon 5: 114,473,054–114,473,164, 111 basesExon 6: 114,487,050–114,487,177, 128 basesExon 7: 114,493,403–114,493,472, 70 basesExon 8: 114,495,895–114,496,496, 602 bases1585′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.8 kb of the gene's 134.4 kb; 2,376 of those bases code for the protein.

How a genome test reads KCNN2

9

positions in KCNN2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 134.4 kb of KCNN2, introns included, not only the 2.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). KCNN2 gene: potassium calcium-activated channel subfamily N member 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/kcnn2

Vancouver

Dante Labs. KCNN2 gene: potassium calcium-activated channel subfamily N member 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kcnn2

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