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Gene

NAA60

N-alpha-acetyltransferase 60, NatF catalytic subunit

Summary

Cytogenetic location
16p13.3
Coordinates
Chromosome 16: 3,443,680–3,486,953 (GRCh38)
Exons
8 exons across 43.3 kb
Protein
242 amino acids
Also known as
FLJ14154, HAT4, NatF, hNaa60
Previous symbols
NAT15
MANE Select transcript
ENST00000407558.9NM_001083601.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated report relevant to this gene

  • Basal Ganglia Calcification

    • Primary Familial Brain Calcification (All Types)

      Umbrella term covering primary familial brain calcification (bilateral striopallidodentate calcinosis), including the dominant SLC20A2, PDGFRB, PDGFB and XPR1 forms and the recessive MYORG and JAM2 forms.

      • 1 GenCC submitter rates it definitive or strong

How NAA60 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 16, with a bracket where NAA60 sits. NAA60 and 35 genes near it on chromosome 16, from 2,965,317 to 3,965,316.Chromosome 1616p13.3p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.33 Mb3.2 Mb3.4 Mb3.6 Mb3.8 MbKREMEN2: 2,963,625–2,968,380, forward strandKREMEN2PKMYT1: 2,968,024–2,980,813, reverse strandPAQR4: 2,969,242–2,973,484, forward strandPAQR4GREP1: 2,988,256–3,002,295, forward strand: 3,004,132–3,004,859, forward strandCLDN9: 3,012,923–3,014,505, forward strandCLDN6: 3,014,705–3,020,071, reverse strandTNFRSF12A: 3,018,445–3,022,385, forward strandTHOC6: 3,022,541–3,027,755, forward strandTHOC6HCFC1R1: 3,022,625–3,024,312, reverse strandHCFC1R1BICDL2: 3,027,682–3,036,993, reverse strandBICDL2MMP25: 3,046,062–3,060,729, forward strandMMP25IL32: 3,064,301–3,082,192, forward strandIL32ZSCAN10: 3,088,888–3,099,370, reverse strandZSCAN10ZNF205: 3,112,550–3,120,527, forward strandZNF205ZNF213: 3,129,777–3,142,804, forward strandZNF213OR1F1: 3,188,204–3,224,779, forward strandOR1F1ZNF200: 3,222,324–3,236,221, reverse strandZNF200MEFV: 3,240,392–3,256,954, reverse strandMEFVZNF263: 3,263,800–3,301,705, forward strandZNF263TIGD7: 3,298,390–3,305,729, reverse strandTIGD7ZNF75A: 3,305,385–3,320,003, forward strandZNF75AOR2C1: 3,355,889–3,357,306, forward strandOR2C1: 3,365,099–3,479,550, forward strandZSCAN32: 3,382,081–3,401,483, reverse strandZSCAN32ZNF174: 3,401,194–3,409,478, forward strandZNF174ZNF597: 3,432,414–3,443,539, reverse strandZNF597NAA60: 3,443,680–3,486,953, forward strandNAA60C16orf90: 3,493,484–3,495,489, reverse strandC16orf90IFT38: 3,500,976–3,540,653, forward strandIFT38NLRC3: 3,538,090–3,577,403, reverse strandNLRC3SLX4: 3,579,654–3,611,617, reverse strandSLX4DNASE1: 3,611,678–3,680,143, forward strandDNASE1TRAP1: 3,651,639–3,717,595, reverse strandTRAP1CREBBP: 3,725,054–3,880,734, reverse strandCREBBPADCY9: 3,953,387–4,116,493, reverse strandADCY9Diagram of NAA60: 8 exons on the forward strand of chromosome 16Exon 1: 3,443,680–3,443,837, 158 basesExon 2: 3,448,471–3,448,540, 70 basesExon 3: 3,476,222–3,476,337, 116 basesExon 4: 3,479,471–3,479,600, 130 basesExon 5: 3,482,502–3,482,598, 97 basesExon 6: 3,483,363–3,483,597, 235 basesExon 7: 3,484,699–3,485,061, 363 basesExon 8: 3,485,467–3,486,953, 1,487 bases123456785′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 43.3 kb; 729 of those bases code for the protein.

Genes linked to the same conditions

Traits linked to NAA60

The Human Phenotype Ontology lists these as features of the rare conditions NAA60 can cause. Each trait's page lists the other genes linked to it.

Abnormality of the nervous system

Show 38 more traits

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NAA60 gene: N-alpha-acetyltransferase 60, NatF catalytic subunit. Retrieved 17 October 2026, from https://dantelabs.com/genes/naa60

Vancouver

Dante Labs. NAA60 gene: N-alpha-acetyltransferase 60, NatF catalytic subunit [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/naa60

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