Gene
RC3H1
ring finger and CCCH-type domains 1
- HGNC 29434↗(opens in a new tab)
- Ensembl gene ENSG00000135870↗(opens in a new tab)
- NCBI Gene 149041↗(opens in a new tab)
Summary
- Cytogenetic location
- 1q25.1
- Coordinates
- Chromosome 1: 173,931,084–174,022,357 (GRCh38)
- Exons
- 20 exons across 91.3 kb
- Protein
- 1,133 amino acids
- Also known as
- KIAA2025, roquin, RP5-1198E17.5, RNF198
- MANE Select transcript
- ENST00000367696.7NM_172071.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How RC3H1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 11.5 kb of the gene's 91.3 kb; 3,402 of those bases code for the protein.
Traits linked to RC3H1
The Human Phenotype Ontology lists these as features of the rare conditions RC3H1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of blood and blood-forming tissues
- Decreased blood leukocyte number
- Decreased blood lymphocyte number
- Hemophagocytosis
- Hypofibrinogenemia
- Increased naive B cell proportion
- Low blood monocyte number
- Low blood neutrophil count
- Low number of red blood cells or hemoglobin
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). RC3H1 gene: ring finger and CCCH-type domains 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/rc3h1
Dante Labs. RC3H1 gene: ring finger and CCCH-type domains 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rc3h1
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