Trait
Elevated lipids in blood
Clinical name: Hyperlipidemia
The concentration of lipid in the blood circulation is above the upper limit of normal.
Summary
- Also called
- Elevated lipid concentration, Elevated lipid level, Elevated lipid level in blood, Increased lipid concentration, Increased lipid level, Increased lipid level in blood
- Body system
- Laboratory abnormality
Reference genomeGRCh38hg38
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Read the genes linked to Elevated lipids in blood, and the rest of your genome, with one test.
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Get my Genome Test45 genes linked to Elevated lipids in blood
Changes in these genes cause rare conditions in which Elevated lipids in blood is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCG5ATP binding cassette subfamily G member 5 | Always | In 1 condition |
| ABCG8ATP binding cassette subfamily G member 8 | Always | In 1 condition |
| APOBapolipoprotein B | Always | In 1 condition |
| DGAT1diacylglycerol O-acyltransferase 1 | Always | In 1 condition |
| G6PC1glucose-6-phosphatase catalytic subunit 1 | Always | In 1 condition |
| LDLRlow density lipoprotein receptor | Always | In 1 condition |
| LDLRAP1low density lipoprotein receptor adaptor protein 1 | Always | In 1 condition |
| PCSK9proprotein convertase subtilisin/kexin type 9 | Always | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Very often (80–99%) | In 1 condition |
| CYP19A1cytochrome P450 family 19 subfamily A member 1 | Very often (80–99%) | In 1 condition |
| DCAF17DDB1 and CUL4 associated factor 17 | Very often (80–99%) | In 2 conditions |
| SLC37A4solute carrier family 37 member 4 | Very often (80–99%) | In 3 conditions |
| ALBalbumin | Often (30–79%) | In 1 condition |
| ARMC5armadillo repeat containing 5 | Often (30–79%) | In 1 condition |
| CPT2carnitine palmitoyltransferase 2 | Often (30–79%) | In 1 condition |
| GLAgalactosidase alpha | Often (30–79%) | In 1 condition |
| GNASGNAS complex locus | Often (30–79%) | In 1 condition |
| HMOX1heme oxygenase 1 | Often (30–79%) | In 1 condition |
| KDM1Alysine demethylase 1A | Often (30–79%) | In 1 condition |
| LIPElipase E, hormone sensitive type | Often (30–79%) | In 1 condition |
| LMNAlamin A/C | Often (30–79%) | In 2 conditions |
| MYO5Amyosin VA | Often (30–79%) | In 1 condition |
| PNPLA2patatin like domain 2, triacylglycerol lipase | Often (30–79%) | In 1 condition |
| RAB27ARAB27A, member RAS oncogene family | Often (30–79%) | In 1 condition |
| SLC25A13solute carrier family 25 member 13 | Often (30–79%) | In 1 condition |
| SMARCAL1SNF2 related chromatin remodeling annealing helicase 1 | Often (30–79%) | In 1 condition |
| SMPD1sphingomyelin phosphodiesterase 1 | Often (30–79%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Often (30–79%) | In 2 conditions |
| CNBPCCHC-type zinc finger nucleic acid binding protein | Sometimes (5–29%) | In 1 condition |
| GYS2glycogen synthase 2 | Sometimes (5–29%) | In 1 condition |
| PYGLglycogen phosphorylase L | Sometimes (5–29%) | In 2 conditions |
| TFGtrafficking from ER to golgi regulator | Sometimes (5–29%) | In 1 condition |
| LMAN1lectin, mannose binding 1 | Rarely (1–4%) | In 1 condition |
| MCFD2multiple coagulation factor deficiency 2, ER cargo receptor complex subunit | Rarely (1–4%) | In 1 condition |
| MYT1Lmyelin transcription factor 1 like | Rarely (1–4%) | In 1 condition |
| ACTN4actinin alpha 4 | Not recorded | In 1 condition |
| ADCY3adenylate cyclase 3 | Not recorded | In 1 condition |
| AGLamylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase | Not recorded | In 1 condition |
| CFHcomplement factor H | Not recorded | In 1 condition |
| CFHR1complement factor H related 1 | Not recorded | In 1 condition |
Show 5 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| CFHR3complement factor H related 3 | Not recorded | In 1 condition |
| LPLlipoprotein lipase | Not recorded | In 2 conditions |
| NPHS1NPHS1 adhesion molecule, nephrin | Not recorded | In 1 condition |
| NPHS2NPHS2 stomatin family member, podocin | Not recorded | In 1 condition |
| SH2B1SH2B adaptor protein 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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