Trait
Nasal speech
Clinical name: Hypernasal speech
A type of speech characterized by the presence of an abnormally increased nasal airflow during speech associated with structural abnormality of the nasal passages.
Summary
- Also called
- Nasal voice, Hypernasal voice
- Body system
- Abnormality of the voice
Reference genomeGRCh38hg38
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Read the genes linked to Nasal speech, and the rest of your genome, with one test.
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Get my Genome Test110 genes linked to Nasal speech
Changes in these genes cause rare conditions in which Nasal speech is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CEP104centrosomal protein 104 | Always | In 1 condition |
| ERI1exoribonuclease 1 | Always | In 1 condition |
| JPH1junctophilin 1 | Always | In 1 condition |
| KDM6Blysine demethylase 6B | Always | In 1 condition |
| MEGF10multiple EGF like domains 10 | Always | In 2 conditions |
| NDC1NDC1 transmembrane nucleoporin | Always | In 1 condition |
| NONOnon-POU domain containing octamer binding | Always | In 2 conditions |
| NOTCH3notch receptor 3 | Always | In 1 condition |
| PABPN1poly(A) binding protein nuclear 1 | Always | In 1 condition |
| PYROXD1pyridine nucleotide-disulphide oxidoreductase domain 1 | Always | In 1 condition |
| SCN4Asodium voltage-gated channel alpha subunit 4 | Always | In 2 conditions |
| SLC18A2solute carrier family 18 member A2 | Always | In 2 conditions |
| TUBB6tubulin beta 6 class V | Always | In 1 condition |
| UNC45Bunc-45 myosin chaperone B | Always | In 1 condition |
| ZBTB18zinc finger and BTB domain containing 18 | Always | In 1 condition |
| ARVCFARVCF delta catenin family member | Very often (80–99%) | In 1 condition |
| ATP6V0A2ATPase H+ transporting V0 subunit a2 | Very often (80–99%) | In 2 conditions |
| CAMKMTcalmodulin-lysine N-methyltransferase | Very often (80–99%) | In 1 condition |
| COMTcatechol-O-methyltransferase | Very often (80–99%) | In 1 condition |
| GP1BBglycoprotein Ib platelet subunit beta | Very often (80–99%) | In 1 condition |
| HIRAhistone cell cycle regulator | Very often (80–99%) | In 1 condition |
| JMJD1Cjumonji domain containing 1C | Very often (80–99%) | In 1 condition |
| MED12mediator complex subunit 12 | Very often (80–99%) | In 2 conditions |
| PCNTpericentrin | Very often (80–99%) | In 1 condition |
| PPM1Bprotein phosphatase, Mg2+/Mn2+ dependent 1B | Very often (80–99%) | In 1 condition |
| PREPLprolyl endopeptidase like | Very often (80–99%) | In 2 conditions |
| RREB1ras responsive element binding protein 1 | Very often (80–99%) | In 1 condition |
| SEC24CSEC24 homolog C, COPII component | Very often (80–99%) | In 1 condition |
| SLC3A1solute carrier family 3 member 1 | Very often (80–99%) | In 2 conditions |
| TBX1T-box transcription factor 1 | Very often (80–99%) | In 4 conditions |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Very often (80–99%) | In 1 condition |
| UPF3BUPF3B regulator of nonsense mediated mRNA decay | Very often (80–99%) | In 2 conditions |
| ZDHHC9zDHHC palmitoyltransferase 9 | Very often (80–99%) | In 1 condition |
| AAASaladin WD repeat nucleoporin | Often (30–79%) | In 1 condition |
| BAG3BAG cochaperone 3 | Often (30–79%) | In 1 condition |
| CAMTA1calmodulin binding transcription activator 1 | Often (30–79%) | In 1 condition |
| CNOT2CCR4-NOT transcription complex subunit 2 | Often (30–79%) | In 1 condition |
| COL9A1collagen type IX alpha 1 chain | Often (30–79%) | In 1 condition |
| GMPPAGDP-mannose pyrophosphorylase A | Often (30–79%) | In 2 conditions |
| GRHL3grainyhead like transcription factor 3 | Often (30–79%) | In 2 conditions |
Show 70 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Often (30–79%) | In 1 condition |
| IL1RAPL1interleukin 1 receptor accessory protein like 1 | Often (30–79%) | In 1 condition |
| IQSEC2IQ motif and Sec7 domain ArfGEF 2 | Often (30–79%) | In 1 condition |
| IRF6interferon regulatory factor 6 | Often (30–79%) | In 2 conditions |
| KANSL1KAT8 regulatory NSL complex subunit 1 | Often (30–79%) | In 1 condition |
| MAGEL2MAGE family member L2 | Often (30–79%) | In 1 condition |
| MATR3matrin 3 | Often (30–79%) | In 1 condition |
| MGME1mitochondrial genome maintenance exonuclease 1 | Often (30–79%) | In 2 conditions |
| MKRN3makorin ring finger protein 3 | Often (30–79%) | In 1 condition |
| MSX1msh homeobox 1 | Often (30–79%) | In 2 conditions |
| MYH3myosin heavy chain 3 | Often (30–79%) | In 2 conditions |
| MYMXmyomixer, myoblast fusion factor | Often (30–79%) | In 1 condition |
| MYOTmyotilin | Often (30–79%) | In 1 condition |
| NALCNsodium leak channel, non-selective | Often (30–79%) | In 1 condition |
| NECTIN1nectin cell adhesion molecule 1 | Often (30–79%) | In 2 conditions |
| NPAP1nuclear pore associated protein 1 | Often (30–79%) | In 1 condition |
| PWAR1Prader Willi/Angelman region RNA 1 | Often (30–79%) | In 1 condition |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Often (30–79%) | In 1 condition |
| RILPL1Rab interacting lysosomal protein like 1 | Often (30–79%) | In 1 condition |
| SHOC2SHOC2 leucine rich repeat scaffold protein | Often (30–79%) | In 1 condition |
| SMSspermine synthase | Often (30–79%) | In 2 conditions |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Often (30–79%) | In 1 condition |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Often (30–79%) | In 1 condition |
| SPG7SPG7 matrix AAA peptidase subunit, paraplegin | Often (30–79%) | In 2 conditions |
| TFAP2Atranscription factor AP-2 alpha | Often (30–79%) | In 2 conditions |
| TP63tumor protein p63 | Often (30–79%) | In 2 conditions |
| TRAPPC11trafficking protein particle complex subunit 11 | Often (30–79%) | In 1 condition |
| UBBubiquitin B | Often (30–79%) | In 2 conditions |
| ARHGAP29Rho GTPase activating protein 29 | Sometimes (5–29%) | In 1 condition |
| ARHGEF38Rho guanine nucleotide exchange factor 38 | Sometimes (5–29%) | In 1 condition |
| ATG7autophagy related 7 | Sometimes (5–29%) | In 1 condition |
| BCL11ABCL11 transcription factor A | Sometimes (5–29%) | In 1 condition |
| BMP4bone morphogenetic protein 4 | Sometimes (5–29%) | In 1 condition |
| CADM3cell adhesion molecule 3 | Sometimes (5–29%) | In 1 condition |
| CDH1cadherin 1 | Sometimes (5–29%) | In 1 condition |
| COBLL1cordon-bleu WH2 repeat protein like 1 | Sometimes (5–29%) | In 1 condition |
| DLG1discs large MAGUK scaffold protein 1 | Sometimes (5–29%) | In 1 condition |
| DLX4distal-less homeobox 4 | Sometimes (5–29%) | In 1 condition |
| FOXP2forkhead box P2 | Sometimes (5–29%) | In 1 condition |
| GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A | Sometimes (5–29%) | In 1 condition |
| MUSKmuscle associated receptor tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| MYPNmyopalladin | Sometimes (5–29%) | In 1 condition |
| PDGFRAplatelet derived growth factor receptor alpha | Sometimes (5–29%) | In 1 condition |
| PLECplectin | Sometimes (5–29%) | In 1 condition |
| POLGDNA polymerase gamma, catalytic subunit | Sometimes (5–29%) | In 1 condition |
| RELREL proto-oncogene, NF-kB subunit | Sometimes (5–29%) | In 1 condition |
| RIC1RIC1 partner of RAB6A GEF complex | Sometimes (5–29%) | In 1 condition |
| SETSET nuclear proto-oncogene | Sometimes (5–29%) | In 1 condition |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Sometimes (5–29%) | In 1 condition |
| SRCAPSnf2 related CREBBP activator protein | Sometimes (5–29%) | In 1 condition |
| SRPX2sushi repeat containing protein X-linked 2 | Sometimes (5–29%) | In 1 condition |
| SYT2synaptotagmin 2 | Sometimes (5–29%) | In 1 condition |
| TPM2tropomyosin 2 | Sometimes (5–29%) | In 1 condition |
| TPM3tropomyosin 3 | Sometimes (5–29%) | In 1 condition |
| TWNKtwinkle mtDNA helicase | Sometimes (5–29%) | In 1 condition |
| XPO1exportin 1 | Sometimes (5–29%) | In 1 condition |
| AMER1APC membrane recruitment protein 1 | Not recorded | In 1 condition |
| CRLF1cytokine receptor like factor 1 | Not recorded | In 1 condition |
| DGCR2DiGeorge syndrome critical region gene 2 | Not recorded | In 1 condition |
| DGCR6DiGeorge syndrome critical region gene 6 | Not recorded | In 1 condition |
| DGCR8DGCR8 microprocessor complex subunit | Not recorded | In 1 condition |
| DYNC1I2dynein cytoplasmic 1 intermediate chain 2 | Not recorded | In 1 condition |
| ESS2ess-2 spliceosome associated protein | Not recorded | In 1 condition |
| LIFRLIF receptor subunit alpha | Not recorded | In 1 condition |
| LRP12LDL receptor related protein 12 | Not recorded | In 1 condition |
| MGPmatrix Gla protein | Not recorded | In 1 condition |
| PHF8PHD finger protein 8 | Not recorded | In 1 condition |
| PQBP1polyglutamine binding protein 1 | Not recorded | In 1 condition |
| SELENONselenoprotein N | Not recorded | In 1 condition |
| SNRPBsmall nuclear ribonucleoprotein polypeptides B and B1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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From $449Free shipping · Results in 6–8 weeks