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Gene

SRPX2

sushi repeat containing protein X-linked 2

Summary

Cytogenetic location
Xq22.1
Coordinates
Chromosome X: 100,644,199–100,675,788 (GRCh38)
Exons
11 exons across 31.6 kb
Protein
465 amino acids
Also known as
SRPUL
MANE Select transcript
ENST00000373004.5NM_014467.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads SRPX2 yet. The test sequences your whole genome, so your data includes it all the same.

How SRPX2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome X, with a bracket where SRPX2 sits. SRPX2 and 11 genes near it on chromosome X, from 100,159,994 to 101,159,993.Chromosome XXq22.1p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q28100.2 Mb100.4 Mb100.6 Mb100.8 Mb101 MbPCDH19: 100,291,644–100,410,296, reverse strandPCDH19TNMD: 100,584,929–100,601,108, forward strandTNMDTSPAN6: 100,627,080–100,639,991, reverse strandTSPAN6SRPX2: 100,644,199–100,675,788, forward strandSRPX2SYTL4: 100,671,783–100,732,154, reverse strandSYTL4CSTF2: 100,820,331–100,843,533, forward strandCSTF2NOX1: 100,843,324–100,874,464, reverse strandNOX1XKRX: 100,886,924–100,929,433, reverse strandXKRXARL13A: 100,969,708–100,990,831, forward strandARL13ATRMT2B: 100,973,670–101,052,135, reverse strandTRMT2BTMEM35A: 101,078,870–101,096,367, forward strandTMEM35ACENPI: 101,098,150–101,166,126, forward strandCENPIDiagram of SRPX2: 11 exons on the forward strand of chromosome XExon 10: 1 known disease-causing siteExon 1: 100,644,199–100,644,515, 317 basesExon 2: 100,646,193–100,646,404, 212 basesExon 3: 100,650,785–100,650,865, 81 basesExon 4: 100,662,176–100,662,367, 192 basesExon 5: 100,664,774–100,664,950, 177 basesExon 6: 100,665,243–100,665,369, 127 basesExon 7: 100,665,536–100,665,657, 122 basesExon 8: 100,666,754–100,666,933, 180 basesExon 9: 100,667,274–100,667,407, 134 basesExon 10: 100,669,248–100,669,369, 122 basesExon 11: 100,670,807–100,675,788, 4,982 bases1246810115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.6 kb of the gene's 31.6 kb; 1,398 of those bases code for the protein.

Sequencing SRPX2

1Low

How hard SRPX2 is to sequence with short reads, out of 100

  • Mappability0%
  • Homology0%
  • Repeats3.1%
  • GC content2.2%
  • Reference coverage0%

1

position in SRPX2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 31.6 kb of SRPX2, introns included, not only the 6.6 kb of exons.

Traits linked to SRPX2

The Human Phenotype Ontology lists these as features of the rare conditions SRPX2 can cause. Each trait's page lists the other genes linked to it.

Abnormality of the nervous system

Show 41 more traits

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

Cite this page

APA

Dante Labs. (n.d.). SRPX2 gene: sushi repeat containing protein X-linked 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/srpx2

Vancouver

Dante Labs. SRPX2 gene: sushi repeat containing protein X-linked 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/srpx2

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