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Trait
Tall stature
A height above that which is expected according to age and gender norms.
Summary
- Also called
- Increased body height, Accelerated linear growth, Increased linear growth
- Body system
- Growth abnormality
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This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/tall-stature.json"
page <- fromJSON(url)
page$trait$nameTall statureHP:0000098
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Get my Genome Test101 genes linked to Tall stature
Changes in these genes cause rare conditions in which Tall stature is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FBN1fibrillin 1 | Always | In 4 conditions |
| FGFR3fibroblast growth factor receptor 3 | Always | In 1 condition |
| HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | Always | In 1 condition |
| MSL2MSL complex subunit 2 | Always | In 1 condition |
| NPR2natriuretic peptide receptor 2 | Always | In 1 condition |
| NPR3natriuretic peptide receptor 3 | Always | In 1 condition |
| NSD1nuclear receptor binding SET domain protein 1 | Always | In 3 conditions |
| SPTAN1spectrin alpha, non-erythrocytic 1 | Always | In 1 condition |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| TCF20transcription factor 20 | Always | In 1 condition |
| UNC13Aunc-13 homolog A | Always | In 1 condition |
| AIPAHR interacting HSP90 co-chaperone | Very often (80–99%) | In 1 condition |
| APC2APC regulator of Wnt signaling pathway 2 | Very often (80–99%) | In 1 condition |
| ARandrogen receptor | Very often (80–99%) | In 1 condition |
| CYP19A1cytochrome P450 family 19 subfamily A member 1 | Very often (80–99%) | In 1 condition |
| DIS3L2DIS3 like 3'-5' exoribonuclease 2 | Very often (80–99%) | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Very often (80–99%) | In 1 condition |
| ESR1estrogen receptor 1 | Very often (80–99%) | In 1 condition |
| EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit | Very often (80–99%) | In 1 condition |
| GPC3glypican 3 | Very often (80–99%) | In 2 conditions |
| GPC4glypican 4 | Very often (80–99%) | In 1 condition |
| LHCGRluteinizing hormone/choriogonadotropin receptor | Very often (80–99%) | In 1 condition |
| LRP4LDL receptor related protein 4 | Very often (80–99%) | In 1 condition |
| MEGF8multiple EGF like domains 8 | Very often (80–99%) | In 1 condition |
| MEN1menin 1 | Very often (80–99%) | In 1 condition |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Very often (80–99%) | In 1 condition |
| PTCH1patched 1 | Very often (80–99%) | In 1 condition |
| RAB23RAB23, member RAS oncogene family | Very often (80–99%) | In 1 condition |
| RNF135ring finger protein 135 | Very often (80–99%) | In 1 condition |
| SHANK3SH3 and multiple ankyrin repeat domains 3 | Very often (80–99%) | In 1 condition |
| SOSTsclerostin | Very often (80–99%) | In 1 condition |
| SUZ12SUZ12 polycomb repressive complex 2 subunit | Very often (80–99%) | In 2 conditions |
| ABAT4-aminobutyrate aminotransferase | Often (30–79%) | In 2 conditions |
| AGGF1angiogenic factor with G-patch and FHA domains 1 | Often (30–79%) | In 1 condition |
| AMOTL1angiomotin like 1 | Often (30–79%) | In 1 condition |
| CHD8chromodomain helicase DNA binding protein 8 | Often (30–79%) | In 1 condition |
| EFEMP1EGF-like fibulin extracellular matrix protein 1 | Often (30–79%) | In 1 condition |
| IPO8importin 8 | Often (30–79%) | In 1 condition |
| MED12mediator complex subunit 12 | Often (30–79%) | In 1 condition |
| NFIXnuclear factor I X | Often (30–79%) | In 2 conditions |
Show 61 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| PDGFRBplatelet derived growth factor receptor beta | Often (30–79%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Often (30–79%) | In 2 conditions |
| PLOD1procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Often (30–79%) | In 1 condition |
| PYROXD1pyridine nucleotide-disulphide oxidoreductase domain 1 | Often (30–79%) | In 1 condition |
| SMAD2SMAD family member 2 | Often (30–79%) | In 3 conditions |
| SMAD3SMAD family member 3 | Often (30–79%) | In 2 conditions |
| SUFUSUFU negative regulator of hedgehog signaling | Often (30–79%) | In 1 condition |
| TGFB2transforming growth factor beta 2 | Often (30–79%) | In 3 conditions |
| TGFB3transforming growth factor beta 3 | Often (30–79%) | In 3 conditions |
| TGFBR1transforming growth factor beta receptor 1 | Often (30–79%) | In 2 conditions |
| TGFBR2transforming growth factor beta receptor 2 | Often (30–79%) | In 2 conditions |
| TRIM32tripartite motif containing 32 | Often (30–79%) | In 1 condition |
| ACTA2actin alpha 2, smooth muscle | Sometimes (5–29%) | In 1 condition |
| BCL11ABCL11 transcription factor A | Sometimes (5–29%) | In 1 condition |
| C1Rcomplement C1r | Sometimes (5–29%) | In 1 condition |
| CCND1cyclin D1 | Sometimes (5–29%) | In 1 condition |
| CRNKL1crooked neck pre-mRNA splicing factor 1 | Sometimes (5–29%) | In 1 condition |
| EFEMP2EGF-like fibulin extracellular matrix protein 2 | Sometimes (5–29%) | In 1 condition |
| EHMT1euchromatic histone lysine methyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| ELNelastin | Sometimes (5–29%) | In 1 condition |
| FBXO11F-box protein 11 | Sometimes (5–29%) | In 1 condition |
| FGF3fibroblast growth factor 3 | Sometimes (5–29%) | In 1 condition |
| FOXE3forkhead box E3 | Sometimes (5–29%) | In 1 condition |
| GLI3GLI family zinc finger 3 | Sometimes (5–29%) | In 1 condition |
| HEY2hes related family bHLH transcription factor with YRPW motif 2 | Sometimes (5–29%) | In 1 condition |
| KIF7kinesin family member 7 | Sometimes (5–29%) | In 1 condition |
| KLHL20kelch like family member 20 | Sometimes (5–29%) | In 1 condition |
| LOXlysyl oxidase | Sometimes (5–29%) | In 1 condition |
| LRRC7leucine rich repeat containing 7 | Sometimes (5–29%) | In 1 condition |
| MAT2Amethionine adenosyltransferase 2A | Sometimes (5–29%) | In 1 condition |
| MC2Rmelanocortin 2 receptor | Sometimes (5–29%) | In 2 conditions |
| MFAP5microfibril associated protein 5 | Sometimes (5–29%) | In 1 condition |
| MRAPmelanocortin 2 receptor accessory protein | Sometimes (5–29%) | In 1 condition |
| MYH11myosin heavy chain 11 | Sometimes (5–29%) | In 1 condition |
| MYLKmyosin light chain kinase | Sometimes (5–29%) | In 1 condition |
| NNTnicotinamide nucleotide transhydrogenase | Sometimes (5–29%) | In 1 condition |
| PAFAH1B1platelet activating factor acetylhydrolase 1b regulatory subunit 1 | Sometimes (5–29%) | In 1 condition |
| PRKG1protein kinase cGMP-dependent 1 | Sometimes (5–29%) | In 1 condition |
| PTENphosphatase and tensin homolog | Sometimes (5–29%) | In 1 condition |
| RELREL proto-oncogene, NF-kB subunit | Sometimes (5–29%) | In 1 condition |
| REREarginine-glutamic acid dipeptide repeats | Sometimes (5–29%) | In 1 condition |
| SMAD4SMAD family member 4 | Sometimes (5–29%) | In 1 condition |
| SRRM2serine/arginine repetitive matrix 2 | Sometimes (5–29%) | In 1 condition |
| STARsteroidogenic acute regulatory protein | Sometimes (5–29%) | In 1 condition |
| THSD4thrombospondin type 1 domain containing 4 | Sometimes (5–29%) | In 1 condition |
| TXNRD2thioredoxin reductase 2 | Sometimes (5–29%) | In 1 condition |
| UPF3BUPF3B regulator of nonsense mediated mRNA decay | Sometimes (5–29%) | In 1 condition |
| XPO1exportin 1 | Sometimes (5–29%) | In 1 condition |
| YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon | Sometimes (5–29%) | In 1 condition |
| PDE11Aphosphodiesterase 11A | Rarely (1–4%) | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Rarely (1–4%) | In 1 condition |
| AGPAT21-acylglycerol-3-phosphate O-acyltransferase 2 | Not recorded | In 1 condition |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Not recorded | In 1 condition |
| CBScystathionine beta-synthase | Not recorded | In 1 condition |
| EEDembryonic ectoderm development | Not recorded | In 1 condition |
| FIBPFGF1 intracellular binding protein | Not recorded | In 1 condition |
| GPR101G protein-coupled receptor 101 | Not recorded | In 1 condition |
| MC4Rmelanocortin 4 receptor | Not recorded | In 1 condition |
| SLC6A8solute carrier family 6 member 8 | Not recorded | In 1 condition |
| SMSspermine synthase | Not recorded | In 1 condition |
| SRYsex determining region Y | Not recorded | In 2 conditions |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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