Gene
FIBP
FGF1 intracellular binding protein
- HGNC 3705↗(opens in a new tab)
- Ensembl gene ENSG00000172500↗(opens in a new tab)
- NCBI Gene 9158↗(opens in a new tab)
Summary
- Cytogenetic location
- 11q13.1
- Coordinates
- Chromosome 11: 65,883,740–65,888,471 (GRCh38)
- Exons
- 10 exons across 4.7 kb
- Protein
- 357 amino acids
- Also known as
- FGFIBP
- MANE Select transcript
- ENST00000357519.9NM_004214.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads FIBP yet. The test sequences your whole genome, so your data includes it all the same.
How FIBP is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.4 kb of the gene's 4.7 kb; 1,074 of those bases code for the protein.
How a genome test reads FIBP
3
positions in FIBP where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 4.7 kb of FIBP, introns included, not only the 1.4 kb of exons.
Traits linked to FIBP
The Human Phenotype Ontology lists these as features of the rare conditions FIBP can cause. Each trait's page lists the other genes linked to it.
Abnormality of limbs
- Fluid accumulation in lower limbs
- Abnormal femoral torsion
- Abnormality of the thumb
- Bowed legs
- Bowed shankbone
- Club feet
- Dropped arches
- Front half of foot turns inward
Show 4 more traits
Abnormality of head or neck
- Abnormally large tongue
- Big calvaria
- Broad opening between the eyelids
- Downward slanting of the opening between the eyelids
- Full lips
- Abnormal facial shape
- Eye folds
- Midface retrusion
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). FIBP gene: FGF1 intracellular binding protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/fibp
Dante Labs. FIBP gene: FGF1 intracellular binding protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/fibp
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