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Gene

SUZ12

SUZ12 polycomb repressive complex 2 subunit

Summary

Cytogenetic location
17q11.2
Coordinates
Chromosome 17: 31,937,007–32,001,038 (GRCh38)
Exons
16 exons across 64 kb
Protein
739 amino acids
Also known as
JJAZ1, KIAA0160, CHET9
MANE Select transcript
ENST00000322652.10NM_015355.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SUZ12 yet. The test sequences your whole genome, so your data includes it all the same.

How SUZ12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where SUZ12 sits. SUZ12 and 9 genes near it on chromosome 17, from 31,469,023 to 32,469,022.Chromosome 1717q11.2p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.331.6 Mb31.8 Mb32 Mb32.2 Mb32.4 MbRAB11FIP4: 31,391,605–31,538,211, forward strandRAB11FIP4COPRS: 31,851,871–31,859,291, reverse strandCOPRSUTP6: 31,860,898–31,901,751, reverse strandUTP6SUZ12: 31,937,007–32,001,038, forward strandSUZ12LRRC37B: 32,007,367–32,053,504, forward strandLRRC37BRHOT1: 32,142,435–32,253,391, forward strandRHOT1RHBDL3: 32,265,787–32,338,568, forward strandRHBDL3C17orf75: 32,324,562–32,350,023, reverse strandC17orf75ZNF207: 32,350,122–32,381,885, forward strandZNF207PSMD11: 32,444,379–32,483,319, forward strandPSMD11Diagram of SUZ12: 16 exons on the forward strand of chromosome 17Exon 3: 2 known disease-causing sitesExon 8: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 10: 3 known disease-causing sitesExon 11: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 14: 2 known disease-causing sitesExon 15: 1 known disease-causing siteExon 16: 1 known disease-causing siteExon 1: 31,937,007–31,937,520, 514 basesExon 2: 31,940,286–31,940,332, 47 basesExon 3: 31,940,422–31,940,486, 65 basesExon 4: 31,947,617–31,947,685, 69 basesExon 5: 31,966,147–31,966,196, 50 basesExon 6: 31,973,146–31,973,231, 86 basesExon 7: 31,975,482–31,975,713, 232 basesExon 8: 31,976,521–31,976,614, 94 basesExon 9: 31,982,999–31,983,104, 106 basesExon 10: 31,988,320–31,988,497, 178 basesExon 11: 31,993,242–31,993,333, 92 basesExon 12: 31,993,865–31,994,008, 144 basesExon 13: 31,994,564–31,994,721, 158 basesExon 14: 31,995,564–31,995,762, 199 basesExon 15: 31,996,798–31,996,877, 80 basesExon 16: 31,998,658–32,001,038, 2,381 bases12468101214165′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.5 kb of the gene's 64 kb; 2,220 of those bases code for the protein.

How a genome test reads SUZ12

16

positions in SUZ12 where ClinVar classes a change as pathogenic or likely pathogenic

5 of them (31%) fall in regions short reads find hard.

  • Low mappability (4 sites)Regions where 100 bp or 250 bp reads cannot be placed uniquely.
  • Segmental duplications (5 sites)Copies of at least 1 kb sharing at least 90% identity with another part of the genome (paralogues, pseudogenes); reads may align to the wrong copy.

A whole genome covers all 64 kb of SUZ12, introns included, not only the 4.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SUZ12 gene: SUZ12 polycomb repressive complex 2 subunit. Retrieved 17 October 2026, from https://dantelabs.com/genes/suz12

Vancouver

Dante Labs. SUZ12 gene: SUZ12 polycomb repressive complex 2 subunit [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/suz12

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