Trait
Slow heartbeats
Clinical name: Bradycardia
A slower than normal heart rate (in adults, slower than 60 beats per minute).
Summary
- Also called
- Brachycardia
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
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Get my Genome Test84 genes linked to Slow heartbeats
Changes in these genes cause rare conditions in which Slow heartbeats is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ACY1aminoacylase 1 | Always | In 1 condition |
| BRAT1BRCA1 associated ATM activator 1 | Always | In 1 condition |
| CACNA1Dcalcium voltage-gated channel subunit alpha1 D | Always | In 1 condition |
| CALM3calmodulin 3 | Always | In 1 condition |
| DHDDSdehydrodolichyl diphosphate synthase subunit | Always | In 1 condition |
| DMRT2doublesex and mab-3 related transcription factor 2 | Always | In 1 condition |
| EFEMP2EGF-like fibulin extracellular matrix protein 2 | Always | In 1 condition |
| FAAP100FA core complex associated protein 100 | Always | In 1 condition |
| GLULglutamate-ammonia ligase | Always | In 1 condition |
| GNB5G protein subunit beta 5 | Always | In 3 conditions |
| GRIN1glutamate ionotropic receptor NMDA type subunit 1 | Always | In 1 condition |
| HCN4hyperpolarization activated cyclic nucleotide gated potassium channel 4 | Always | In 1 condition |
| MPV17mitochondrial inner membrane protein MPV17 | Always | In 1 condition |
| MTO1mitochondrial tRNA translation optimization 1 | Always | In 1 condition |
| NDUFA2NADH:ubiquinone oxidoreductase subunit A2 | Always | In 1 condition |
| SCN4Asodium voltage-gated channel alpha subunit 4 | Always | In 1 condition |
| SCO1synthesis of cytochrome C oxidase 1 | Always | In 1 condition |
| SGO1shugoshin 1 | Always | In 1 condition |
| TM2D3TM2 domain containing 3 | Always | In 1 condition |
| UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | Always | In 1 condition |
| CACNA1Ccalcium voltage-gated channel subunit alpha1 C | Very often (80–99%) | In 1 condition |
| CACNA2D1calcium voltage-gated channel auxiliary subunit alpha2delta 1 | Very often (80–99%) | In 1 condition |
| KCNH2potassium voltage-gated channel subfamily H member 2 | Very often (80–99%) | In 1 condition |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Very often (80–99%) | In 1 condition |
| KCNQ1potassium voltage-gated channel subfamily Q member 1 | Very often (80–99%) | In 2 conditions |
| SCN5Asodium voltage-gated channel alpha subunit 5 | Very often (80–99%) | In 2 conditions |
| SLC4A3solute carrier family 4 member 3 | Very often (80–99%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Often (30–79%) | In 1 condition |
| CALM2calmodulin 2 | Often (30–79%) | In 1 condition |
| COQ4coenzyme Q4 | Often (30–79%) | In 1 condition |
| DSTdystonin | Often (30–79%) | In 2 conditions |
| ECHS1enoyl-CoA hydratase, short chain 1 | Often (30–79%) | In 1 condition |
| GBE11,4-alpha-glucan branching enzyme 1 | Often (30–79%) | In 1 condition |
| GFM2GTP dependent ribosome recycling factor mitochondrial 2 | Often (30–79%) | In 1 condition |
| GLYCTKglycerate kinase | Often (30–79%) | In 1 condition |
| HESX1HESX homeobox 1 | Often (30–79%) | In 1 condition |
| IFNGinterferon gamma | Often (30–79%) | In 1 condition |
| LHX3LIM homeobox 3 | Often (30–79%) | In 1 condition |
| LHX4LIM homeobox 4 | Often (30–79%) | In 1 condition |
| MMACHCmetabolism of cobalamin associated C | Often (30–79%) | In 1 condition |
Show 44 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| NDUFA8NADH:ubiquinone oxidoreductase subunit A8 | Often (30–79%) | In 1 condition |
| POU1F1POU class 1 homeobox 1 | Often (30–79%) | In 1 condition |
| PPA2inorganic pyrophosphatase 2 | Often (30–79%) | In 1 condition |
| PRDX1peroxiredoxin 1 | Often (30–79%) | In 1 condition |
| PRKAG2protein kinase AMP-activated non-catalytic subunit gamma 2 | Often (30–79%) | In 1 condition |
| PROP1PROP paired-like homeobox 1 | Often (30–79%) | In 1 condition |
| SCO2synthesis of cytochrome C oxidase 2 | Often (30–79%) | In 1 condition |
| TSC2TSC complex subunit 2 | Often (30–79%) | In 1 condition |
| ABCA3ATP binding cassette subfamily A member 3 | Sometimes (5–29%) | In 1 condition |
| ACTA1actin alpha 1, skeletal muscle | Sometimes (5–29%) | In 1 condition |
| CRELD1CRELD disulfide isomerase 1 | Sometimes (5–29%) | In 1 condition |
| DESdesmin | Sometimes (5–29%) | In 1 condition |
| DOLKdolichol kinase | Sometimes (5–29%) | In 1 condition |
| DUOX2dual oxidase 2 | Sometimes (5–29%) | In 1 condition |
| DUOXA2dual oxidase maturation factor 2 | Sometimes (5–29%) | In 1 condition |
| HTRA2HtrA serine peptidase 2 | Sometimes (5–29%) | In 1 condition |
| IYDiodotyrosine deiodinase | Sometimes (5–29%) | In 1 condition |
| MYL4myosin light chain 4 | Sometimes (5–29%) | In 1 condition |
| NFU1NFU1 iron-sulfur cluster scaffold | Sometimes (5–29%) | In 1 condition |
| NPPAnatriuretic peptide A | Sometimes (5–29%) | In 2 conditions |
| SFTPBsurfactant protein B | Sometimes (5–29%) | In 1 condition |
| SFTPCsurfactant protein C | Sometimes (5–29%) | In 1 condition |
| SLC5A5solute carrier family 5 member 5 | Sometimes (5–29%) | In 1 condition |
| TANGO2transport and golgi organization 2 homolog | Sometimes (5–29%) | In 1 condition |
| TGthyroglobulin | Sometimes (5–29%) | In 1 condition |
| TLL1tolloid like 1 | Sometimes (5–29%) | In 1 condition |
| TPOthyroid peroxidase | Sometimes (5–29%) | In 1 condition |
| TSHBthyroid stimulating hormone subunit beta | Sometimes (5–29%) | In 1 condition |
| TSHRthyroid stimulating hormone receptor | Sometimes (5–29%) | In 1 condition |
| TWNKtwinkle mtDNA helicase | Sometimes (5–29%) | In 1 condition |
| USP18ubiquitin specific peptidase 18 | Sometimes (5–29%) | In 1 condition |
| LAMA3laminin subunit alpha 3 | Rarely (1–4%) | In 1 condition |
| LAMB3laminin subunit beta 3 | Rarely (1–4%) | In 1 condition |
| LAMC2laminin subunit gamma 2 | Rarely (1–4%) | In 1 condition |
| CASQ2calsequestrin 2 | Not recorded | In 1 condition |
| CAVIN1caveolae associated protein 1 | Not recorded | In 1 condition |
| COQ9coenzyme Q9 | Not recorded | In 1 condition |
| LIPT1lipoyltransferase 1 | Not recorded | In 1 condition |
| PAX8paired box 8 | Not recorded | In 1 condition |
| SCN9Asodium voltage-gated channel alpha subunit 9 | Not recorded | In 1 condition |
| SLC25A20solute carrier family 25 member 20 | Not recorded | In 1 condition |
| TMEM43transmembrane protein 43 | Not recorded | In 1 condition |
| TRPM4transient receptor potential cation channel subfamily M member 4 | Not recorded | In 1 condition |
| TSPYL1TSPY like 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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