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Gene

CACNA2D1

calcium voltage-gated channel auxiliary subunit alpha2delta 1

Summary

Cytogenetic location
7q21.11
Coordinates
Chromosome 7: 81,946,444–82,443,777 (GRCh38)
Exons
39 exons across 497.3 kb
Protein
1,091 amino acids
Also known as
lncRNA-N3, alpha2delta-1
Previous symbols
CACNL2A, CACNA2, MHS3, LINC01112
MANE Select transcript
ENST00000356860.8NM_000722.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CACNA2D1 yet. The test sequences your whole genome, so your data includes it all the same.

How CACNA2D1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where CACNA2D1 sits. CACNA2D1 and 2 genes near it on chromosome 7, from 81,449,110 to 82,941,111.Chromosome 77q21.11p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.381.6 Mb81.8 Mb82 Mb82.2 Mb82.4 Mb82.6 Mb82.8 MbHGF: 81,699,010–81,770,438, reverse strandHGFCACNA2D1: 81,946,444–82,443,777, reverse strandCACNA2D1PCLO: 82,754,012–83,162,930, reverse strandPCLODiagram of CACNA2D1: 39 exons on the reverse strand of chromosome 7Exon 19: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 39: 81,946,444–81,950,508, 4,065 basesExon 38: 81,959,275–81,959,357, 83 basesExon 37: 81,959,720–81,959,829, 110 basesExon 36: 81,961,894–81,962,023, 130 basesExon 35: 81,962,440–81,962,495, 56 basesExon 34: 81,964,056–81,964,108, 53 basesExon 33: 81,964,207–81,964,359, 153 basesExon 32: 81,965,594–81,965,665, 72 basesExon 31: 81,967,169–81,967,207, 39 basesExon 30: 81,967,596–81,967,663, 68 basesExon 29: 81,968,887–81,968,973, 87 basesExon 28: 81,969,881–81,969,984, 104 basesExon 27: 81,970,675–81,970,737, 63 basesExon 26: 81,971,777–81,971,864, 88 basesExon 25: 81,974,455–81,974,552, 98 basesExon 24: 81,982,567–81,982,627, 61 basesExon 23: 81,983,314–81,983,334, 21 basesExon 22: 81,984,635–81,984,711, 77 basesExon 21: 81,991,185–81,991,246, 62 basesExon 20: 81,994,868–81,994,939, 72 basesExon 19: 81,997,179–81,997,250, 72 basesExon 18: 82,005,423–82,005,497, 75 basesExon 17: 82,005,765–82,005,839, 75 basesExon 16: 82,007,679–82,007,756, 78 basesExon 15: 82,012,154–82,012,243, 90 basesExon 14: 82,013,461–82,013,510, 50 basesExon 13: 82,014,401–82,014,479, 79 basesExon 12: 82,032,797–82,032,901, 105 basesExon 11: 82,038,077–82,038,235, 159 basesExon 10: 82,060,428–82,060,527, 100 basesExon 9: 82,064,304–82,064,354, 51 basesExon 8: 82,066,455–82,066,524, 70 basesExon 7: 82,084,769–82,084,900, 132 basesExon 6: 82,117,044–82,117,173, 130 basesExon 5: 82,136,635–82,136,676, 42 basesExon 4: 82,170,550–82,170,609, 60 basesExon 3: 82,335,135–82,335,251, 117 basesExon 2: 82,349,568–82,349,649, 82 basesExon 1: 82,443,365–82,443,777, 413 bases3930201015′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.5 kb of the gene's 497.3 kb; 3,276 of those bases code for the protein.

How a genome test reads CACNA2D1

3

positions in CACNA2D1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 497.3 kb of CACNA2D1, introns included, not only the 7.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CACNA2D1 gene: calcium voltage-gated channel auxiliary subunit alpha2delta 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/cacna2d1

Vancouver

Dante Labs. CACNA2D1 gene: calcium voltage-gated channel auxiliary subunit alpha2delta 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/cacna2d1

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