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Gene

NFU1

NFU1 iron-sulfur cluster scaffold

Summary

Cytogenetic location
2p13.3
Coordinates
Chromosome 2: 69,396,126–69,437,435 (GRCh38)
Exons
8 exons across 41.3 kb
Protein
254 amino acids
Also known as
CGI-33, NifU, NIFUC
Previous symbols
HIRIP5
MANE Select transcript
ENST00000410022.7NM_001002755.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NFU1 yet. The test sequences your whole genome, so your data includes it all the same.

How NFU1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where NFU1 sits. NFU1 and 10 genes near it on chromosome 2, from 68,916,781 to 69,916,780.Chromosome 22p13.3p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.369 Mb69.2 Mb69.4 Mb69.6 Mb69.8 MbGKN2: 68,938,776–68,953,028, reverse strandGKN2GKN1: 68,974,573–68,980,980, forward strandGKN1ANTXR1: 69,013,085–69,249,327, forward strandANTXR1GFPT1: 69,319,616–69,387,313, reverse strandGFPT1NFU1: 69,396,126–69,437,435, reverse strandNFU1AAK1: 69,457,559–69,674,349, reverse strandAAK1ANXA4: 69,643,109–69,827,121, forward strandANXA4GMCL1: 69,829,612–69,881,393, forward strandGMCL1: 69,829,739–69,829,798, forward strandSNRNP27: 69,893,944–69,907,658, forward strandSNRNP27MXD1: 69,897,688–69,942,945, forward strandMXD1Diagram of NFU1: 8 exons on the reverse strand of chromosome 2Exon 7: 2 known disease-causing sitesExon 6: 3 known disease-causing sitesExon 3: 1 known disease-causing siteExon 8: 69,396,126–69,396,290, 165 basesExon 7: 69,400,364–69,400,538, 175 basesExon 6: 69,406,022–69,406,082, 61 basesExon 5: 69,415,185–69,415,299, 115 basesExon 4: 69,419,538–69,419,604, 67 basesExon 3: 69,423,582–69,423,717, 136 basesExon 2: 69,431,902–69,432,005, 104 basesExon 1: 69,437,361–69,437,435, 75 bases876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.9 kb of the gene's 41.3 kb; 765 of those bases code for the protein.

How a genome test reads NFU1

10

positions in NFU1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 41.3 kb of NFU1, introns included, not only the 0.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NFU1 gene: NFU1 iron-sulfur cluster scaffold. Retrieved 17 October 2026, from https://dantelabs.com/genes/nfu1

Vancouver

Dante Labs. NFU1 gene: NFU1 iron-sulfur cluster scaffold [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nfu1

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