Trait
Sinus bradycardia
Bradycardia related to a mean resting sinus rate of less than 50 beats per minute.
Summary
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test23 genes linked to Sinus bradycardia
Changes in these genes cause rare conditions in which Sinus bradycardia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CALM2calmodulin 2 | Always | In 1 condition |
| DSTdystonin | Always | In 1 condition |
| EMDemerin | Always | In 1 condition |
| FEM1Bfem-1 homolog B | Always | In 1 condition |
| GFM2GTP dependent ribosome recycling factor mitochondrial 2 | Always | In 1 condition |
| HCN4hyperpolarization activated cyclic nucleotide gated potassium channel 4 | Always | In 1 condition |
| HEPHL1hephaestin like 1 | Always | In 1 condition |
| KCNE1potassium voltage-gated channel subfamily E regulatory subunit 1 | Always | In 1 condition |
| TBX5T-box transcription factor 5 | Always | In 1 condition |
| CAV3caveolin 3 | Often (30–79%) | In 1 condition |
| GNB2G protein subunit beta 2 | Often (30–79%) | In 1 condition |
| MYO1Hmyosin IH | Often (30–79%) | In 1 condition |
| POPDC1popeye domain cAMP effector 1 | Often (30–79%) | In 1 condition |
| POPDC2popeye domain cAMP effector 2 | Often (30–79%) | In 1 condition |
| ALPK3alpha kinase 3 | Sometimes (5–29%) | In 1 condition |
| CACNA1Ccalcium voltage-gated channel subunit alpha1 C | Sometimes (5–29%) | In 1 condition |
| KCNA5potassium voltage-gated channel subfamily A member 5 | Sometimes (5–29%) | In 1 condition |
| LMNAlamin A/C | Sometimes (5–29%) | In 1 condition |
| TNNT2troponin T2, cardiac type | Sometimes (5–29%) | In 1 condition |
| ANK2ankyrin 2 | Rarely (1–4%) | In 1 condition |
| PRKAG2protein kinase AMP-activated non-catalytic subunit gamma 2 | Not recorded | In 1 condition |
| SCN5Asodium voltage-gated channel alpha subunit 5 | Not recorded | In 1 condition |
| TNNI3KTNNI3 interacting kinase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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