Gene
TM2D3
TM2 domain containing 3
- HGNC 24128↗(opens in a new tab)
- Ensembl gene ENSG00000184277↗(opens in a new tab)
- NCBI Gene 80213↗(opens in a new tab)
Summary
- Cytogenetic location
- 15q26.3
- Coordinates
- Chromosome 15: 101,641,848–101,652,381 (GRCh38)
- Exons
- 6 exons across 10.5 kb
- Protein
- 247 amino acids
- Also known as
- BLP2, FLJ22604
- MANE Select transcript
- ENST00000333202.8NM_078474.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read TM2D3, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads TM2D3 yet. The test sequences your whole genome, so your data includes it all the same.
How TM2D3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.4 kb of the gene's 10.5 kb; 744 of those bases code for the protein.
Traits linked to TM2D3
The Human Phenotype Ontology lists these as features of the rare conditions TM2D3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Abnormal cortical gyration
- Absent speech development
- Aggressive behavior
- Cerebellar vermis hypoplasia
- Delayed ability to walk
- Delayed speech and language development
- Difficulty staying asleep
- Episodic hemiplegia
Show 18 more traits
- Fluid-filled cyst in spinal cord
- Inability to coordinate movements when walking
- Irritability
- Pauses in breathing while sleeping
- Repetitive movements
- Seizure affecting one half of brain
- Self-injurious behavior
- Severe global developmental delay
- Tearfulness
- Teeth grinding
- Thick corpus callosum
- Underdeveloped frontal lobe
- Wide based walk
- Agitation
- Anxiety
- Autism spectrum disorder
- Dystonia
- Epilepsy
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). TM2D3 gene: TM2 domain containing 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/tm2d3
Dante Labs. TM2D3 gene: TM2 domain containing 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tm2d3
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks