Traits

Traits linked to DVL3

dishevelled segment polarity protein 3

The Human Phenotype Ontology links 105 traits to DVL3, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of head or neck

Trait	Kuinka usein sitä esiintyy
Cleft tongue	Aina
Gum enlargement	Aina
Midface retrusion	Aina
Nasal tip, upturned	Aina
Short nose	Aina
Wide nasal bridge	Aina
Wide nose	Hyvin usein (80–99%)
Abnormality of the gums	Usein (30–79%)
Absence of adult teeth	Usein (30–79%)
Big calvaria	Usein (30–79%)
Broad opening between the eyelids	Usein (30–79%)
Central cleft palate	Usein (30–79%)
Cleft palate	Usein (30–79%)
Corners of eye widely separated	Usein (30–79%)
Curly eyelashes	Usein (30–79%)
Depressed nasal bridge	Usein (30–79%)
Downturned corners of mouth	Usein (30–79%)
Euryblepharon	Usein (30–79%)
Eye folds	Usein (30–79%)
Frontal bossing	Usein (30–79%)
High, narrow palate	Usein (30–79%)
Little lower jaw	Usein (30–79%)
Long eyelashes	Usein (30–79%)
Long philtrum	Usein (30–79%)
Open bite	Usein (30–79%)
Prominent forehead	Usein (30–79%)
Receding chin	Usein (30–79%)
Upward slanting of the opening between the eyelids	Usein (30–79%)
Bad bite	Joskus (5–29%)
Cleft lip	Joskus (5–29%)
Downward slanting of the opening between the eyelids	Joskus (5–29%)
Extra teeth	Joskus (5–29%)
Failure of development of all teeth	Joskus (5–29%)
Failure of development of between one and six teeth	Joskus (5–29%)
Failure of development of more than six teeth	Joskus (5–29%)
High forehead	Joskus (5–29%)
Short neck	Joskus (5–29%)
Short philtrum	Joskus (5–29%)
Triangular mouth	Joskus (5–29%)
Webbed neck	Joskus (5–29%)

Abnormality of limbs

Trait	Kuinka usein sitä esiintyy
Curvature of digit	Aina
Disproportionately short middle portion of limb	Aina
Short fingers or toes	Aina
Short palm	Hyvin usein (80–99%)
Smaller or shorter than typical limbs	Hyvin usein (80–99%)
Curvature of little finger	Usein (30–79%)
Short finger bones	Usein (30–79%)
Avascular necrosis of the capital femoral epiphysis	Joskus (5–29%)
Broad thumb	Joskus (5–29%)
Coxa valga	Joskus (5–29%)
Coxa vara	Joskus (5–29%)
Elbow dislocation	Joskus (5–29%)
Finger syndactyly	Joskus (5–29%)
Hip dislocation	Joskus (5–29%)
Permanent flexion of the finger	Joskus (5–29%)
Webbed fingers or toes	Joskus (5–29%)

Abnormality of the genitourinary system

Trait	Kuinka usein sitä esiintyy
Short penis	Aina
Undescended testes	Aina
Underdeveloped penis	Hyvin usein (80–99%)
Small clitoris	Usein (30–79%)
Small labia majora	Usein (30–79%)
Underdeveloped inner lips	Usein (30–79%)
Abnormality of the penis	Joskus (5–29%)
Epispadias	Joskus (5–29%)
Hypospadias	Joskus (5–29%)
Vesicoureteral reflux	Joskus (5–29%)

Abnormality of the musculoskeletal system

Trait	Kuinka usein sitä esiintyy
Abnormal vertebral body morphology	Usein (30–79%)
Funnel chest	Usein (30–79%)
Hunched back	Usein (30–79%)
Missing part of vertebrae	Usein (30–79%)
Scoliosis	Usein (30–79%)
Abnormal formation of the hip	Joskus (5–29%)
Permanent flexion of the finger or toe	Joskus (5–29%)
Pigeon chest	Joskus (5–29%)

Abnormality of the cardiovascular system

Trait	Kuinka usein sitä esiintyy
Hole in heart wall separating two lower heart chambers	Usein (30–79%)
Patent ductus arteriosus	Joskus (5–29%)
Patent foramen ovale	Joskus (5–29%)
Pulmonary artery atresia	Joskus (5–29%)
Strawberry birthmark	Joskus (5–29%)
Tricuspid regurgitation	Joskus (5–29%)
Underdeveloped right heart	Joskus (5–29%)

Abnormality of the integument

Trait	Kuinka usein sitä esiintyy
Abnormal fingernail development	Joskus (5–29%)
Hair loss	Joskus (5–29%)
Overgrowth and curving of fingernail	Joskus (5–29%)
Port-wine stain on eyelid	Joskus (5–29%)
Ridged fingernail	Joskus (5–29%)
Spinal dimple	Joskus (5–29%)

Abnormality of the digestive system

Trait	Kuinka usein sitä esiintyy
Umbilical hernia	Usein (30–79%)
Anteriorly placed anus	Joskus (5–29%)
Femoral hernia	Joskus (5–29%)
Inguinal hernia	Joskus (5–29%)
Omphalocele	Joskus (5–29%)

Abnormality of the eye

Trait	Kuinka usein sitä esiintyy
Wide-set eyes	Hyvin usein (80–99%)
Blue outer white part of eyeball	Usein (30–79%)
Bulging eye	Usein (30–79%)
Cross-eyed	Joskus (5–29%)
Drooping upper eyelid	Joskus (5–29%)

Abnormality of the ear

Trait	Kuinka usein sitä esiintyy
Ears rotated toward back of head	Joskus (5–29%)
Hearing impairment	Joskus (5–29%)
Low-set ears	Joskus (5–29%)

Abnormality of the nervous system

Trait	Kuinka usein sitä esiintyy
Global developmental delay	Joskus (5–29%)
Intellectual disability	Joskus (5–29%)
Specific learning disability	Joskus (5–29%)

Growth abnormality

Trait	Kuinka usein sitä esiintyy
Short stature	Aina
Severe short stature	Usein (30–79%)

Kuinka usein ilmiö esiintyy ihmisillä, joilla on jokin geenin sairauksista, niin kuin Human Phenotype Ontology sen kirjaa. Nämä sivut kuvaavat piirteitä ja niiden taustalla olevaa tutkimusta, eivätkä ne ole diagnoosi. Oireista kannattaa kysyä lääkäriltä tai geneettiseltä neuvojalta.

Mistä tämä tieto tulee

The Human Phenotype Ontology, release 2026-09-01: the traits linked to DVL3 and how often each is seen. Find out more at hpo.jax.org.

Yksi testi. Vastauksia koko elämäksi.

Alkaen 449 $Ilmainen toimitus · Tulokset 6–8 viikossa

Tilaa Genome Test