Trait
Tetraparesis
Weakness of all four limbs.
Summary
- Also called
- Quadriparesis
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test64 genes linked to Tetraparesis
Changes in these genes cause rare conditions in which Tetraparesis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AIFM1apoptosis inducing factor mitochondria associated 1 | Always | In 1 condition |
| CARS2cysteinyl-tRNA synthetase 2, mitochondrial | Always | In 2 conditions |
| COL4A2collagen type IV alpha 2 chain | Always | In 1 condition |
| DNM1Ldynamin 1L | Always | In 1 condition |
| GTF3C3general transcription factor IIIC subunit 3 | Always | In 1 condition |
| GTPBP1GTP binding protein 1 | Always | In 1 condition |
| LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated | Always | In 1 condition |
| PTPMT1protein tyrosine phosphatase mitochondrial 1 | Always | In 1 condition |
| RRP12ribosomal RNA processing 12 homolog | Always | In 1 condition |
| SLC25A10solute carrier family 25 member 10 | Always | In 1 condition |
| TMEM63Btransmembrane protein 63B | Always | In 1 condition |
| VCPvalosin containing protein | Always | In 3 conditions |
| GTPBP2GTP binding protein 2 | Very often (80–99%) | In 1 condition |
| NEXMIFneurite extension and migration factor | Very often (80–99%) | In 1 condition |
| ADARadenosine deaminase RNA specific | Often (30–79%) | In 1 condition |
| AGTPBP1ATP/GTP binding carboxypeptidase 1 | Often (30–79%) | In 1 condition |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Often (30–79%) | In 1 condition |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Often (30–79%) | In 1 condition |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Often (30–79%) | In 1 condition |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Often (30–79%) | In 1 condition |
| FUSFUS RNA binding protein | Often (30–79%) | In 1 condition |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Often (30–79%) | In 1 condition |
| MT-TL2mitochondrially encoded tRNA-Leu (CUN) 2 | Often (30–79%) | In 1 condition |
| NAXENAD(P)HX epimerase | Often (30–79%) | In 1 condition |
| NEK1NIMA related kinase 1 | Often (30–79%) | In 1 condition |
| NMNAT1nicotinamide nucleotide adenylyltransferase 1 | Often (30–79%) | In 1 condition |
| NUP54nucleoporin 54 | Often (30–79%) | In 1 condition |
| NUP62nucleoporin 62 | Often (30–79%) | In 1 condition |
| PDHXpyruvate dehydrogenase complex component X | Often (30–79%) | In 1 condition |
| POLGDNA polymerase gamma, catalytic subunit | Often (30–79%) | In 1 condition |
| POLR3KRNA polymerase III subunit K | Often (30–79%) | In 1 condition |
| PPOXprotoporphyrinogen oxidase | Often (30–79%) | In 1 condition |
| RHOBTB2Rho related BTB domain containing 2 | Often (30–79%) | In 1 condition |
| SCN2Asodium voltage-gated channel alpha subunit 2 | Often (30–79%) | In 1 condition |
| SLC19A3solute carrier family 19 member 3 | Often (30–79%) | In 2 conditions |
| SLC1A2solute carrier family 1 member 2 | Often (30–79%) | In 1 condition |
| SLC1A3solute carrier family 1 member 3 | Often (30–79%) | In 1 condition |
| SLC2A1solute carrier family 2 member 1 | Often (30–79%) | In 1 condition |
| SQSTM1sequestosome 1 | Often (30–79%) | In 1 condition |
| TARDBPTAR DNA binding protein | Often (30–79%) | In 1 condition |
Show 24 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| TBK1TANK binding kinase 1 | Often (30–79%) | In 1 condition |
| TUBB2Btubulin beta 2B class IIb | Often (30–79%) | In 1 condition |
| UNC13Aunc-13 homolog A | Often (30–79%) | In 1 condition |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Sometimes (5–29%) | In 2 conditions |
| GAD1glutamate decarboxylase 1 | Sometimes (5–29%) | In 1 condition |
| HINT1histidine triad nucleotide binding protein 1 | Sometimes (5–29%) | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Sometimes (5–29%) | In 1 condition |
| LMNB1lamin B1 | Sometimes (5–29%) | In 1 condition |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Sometimes (5–29%) | In 1 condition |
| SARDHsarcosine dehydrogenase | Sometimes (5–29%) | In 1 condition |
| UGP2UDP-glucose pyrophosphorylase 2 | Sometimes (5–29%) | In 1 condition |
| CA2carbonic anhydrase 2 | Rarely (1–4%) | In 1 condition |
| GALCgalactosylceramidase | Rarely (1–4%) | In 1 condition |
| ARFGEF2ARF guanine nucleotide exchange factor 2 | Not recorded | In 1 condition |
| C9orf72C9orf72-SMCR8 complex subunit | Not recorded | In 1 condition |
| COL4A1collagen type IV alpha 1 chain | Not recorded | In 1 condition |
| GBE11,4-alpha-glucan branching enzyme 1 | Not recorded | In 1 condition |
| GJA1gap junction protein alpha 1 | Not recorded | In 1 condition |
| LIMS2LIM zinc finger domain containing 2 | Not recorded | In 1 condition |
| LRP4LDL receptor related protein 4 | Not recorded | In 1 condition |
| NDUFS3NADH:ubiquinone oxidoreductase core subunit S3 | Not recorded | In 1 condition |
| PNPpurine nucleoside phosphorylase | Not recorded | In 1 condition |
| TNFRSF11ATNF receptor superfamily member 11a | Not recorded | In 1 condition |
| UCHL1ubiquitin C-terminal hydrolase L1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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