Trait
Difficulty getting a full erection
Clinical name: Impotence
Inability to develop or maintain an erection of the penis.
Summary
- Also called
- Difficulty getting an erection
- Body system
- Abnormality of the genitourinary system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test62 genes linked to Difficulty getting a full erection
Changes in these genes cause rare conditions in which Difficulty getting a full erection is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FMR1fragile X messenger ribonucleoprotein 1 | Always | In 2 conditions |
| AIPAHR interacting HSP90 co-chaperone | Very often (80–99%) | In 2 conditions |
| CDH23cadherin related 23 | Very often (80–99%) | In 2 conditions |
| CHD7chromodomain helicase DNA binding protein 7 | Very often (80–99%) | In 1 condition |
| DUSP6dual specificity phosphatase 6 | Very often (80–99%) | In 1 condition |
| EMX2empty spiracles homeobox 2 | Very often (80–99%) | In 1 condition |
| FGF17fibroblast growth factor 17 | Very often (80–99%) | In 1 condition |
| FGF8fibroblast growth factor 8 | Very often (80–99%) | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Very often (80–99%) | In 1 condition |
| GNRH1gonadotropin releasing hormone 1 | Very often (80–99%) | In 1 condition |
| GNRHRgonadotropin releasing hormone receptor | Very often (80–99%) | In 1 condition |
| HS6ST1heparan sulfate 6-O-sulfotransferase 1 | Very often (80–99%) | In 1 condition |
| KISS1KiSS-1 metastasis suppressor | Very often (80–99%) | In 1 condition |
| KISS1RKISS1 receptor | Very often (80–99%) | In 1 condition |
| MEN1menin 1 | Very often (80–99%) | In 2 conditions |
| NHLH2nescient helix-loop-helix 2 | Very often (80–99%) | In 1 condition |
| NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor | Very often (80–99%) | In 1 condition |
| PROK2prokineticin 2 | Very often (80–99%) | In 1 condition |
| PROKR2prokineticin receptor 2 | Very often (80–99%) | In 1 condition |
| SPRY4sprouty RTK signaling antagonist 4 | Very often (80–99%) | In 1 condition |
| TAC3tachykinin precursor 3 | Very often (80–99%) | In 1 condition |
| TACR3tachykinin receptor 3 | Very often (80–99%) | In 1 condition |
| WDR11WD repeat domain 11 | Very often (80–99%) | In 1 condition |
| AKT1AKT serine/threonine kinase 1 | Often (30–79%) | In 1 condition |
| ATXN8ataxin 8 | Often (30–79%) | In 1 condition |
| ATXN8OSATXN8 opposite strand lncRNA | Often (30–79%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Often (30–79%) | In 1 condition |
| CDKN1Bcyclin dependent kinase inhibitor 1B | Often (30–79%) | In 1 condition |
| CDKN2Bcyclin dependent kinase inhibitor 2B | Often (30–79%) | In 1 condition |
| HAMPhepcidin antimicrobial peptide | Often (30–79%) | In 1 condition |
| HJVhemojuvelin BMP co-receptor | Often (30–79%) | In 1 condition |
| NF2NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor | Often (30–79%) | In 1 condition |
| PDGFBplatelet derived growth factor subunit B | Often (30–79%) | In 2 conditions |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Often (30–79%) | In 1 condition |
| SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1 | Often (30–79%) | In 1 condition |
| SMARCE1SWI/SNF related BAF chromatin remodeling complex subunit E1 | Often (30–79%) | In 1 condition |
| SMOsmoothened, frizzled class receptor | Often (30–79%) | In 1 condition |
| SUFUSUFU negative regulator of hedgehog signaling | Often (30–79%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TRAF7TNF receptor associated factor 7 | Often (30–79%) | In 1 condition |
Show 22 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| TTRtransthyretin | Often (30–79%) | In 2 conditions |
| CACNA1Gcalcium voltage-gated channel subunit alpha1 G | Sometimes (5–29%) | In 1 condition |
| CMPK2cytidine/uridine monophosphate kinase 2 | Sometimes (5–29%) | In 1 condition |
| GPR101G protein-coupled receptor 101 | Sometimes (5–29%) | In 1 condition |
| JAM2junctional adhesion molecule 2 | Sometimes (5–29%) | In 1 condition |
| LMNB1lamin B1 | Sometimes (5–29%) | In 1 condition |
| MYORGmyogenesis regulating glycosidase | Sometimes (5–29%) | In 1 condition |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Sometimes (5–29%) | In 1 condition |
| PDGFRBplatelet derived growth factor receptor beta | Sometimes (5–29%) | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Sometimes (5–29%) | In 1 condition |
| RRP12ribosomal RNA processing 12 homolog | Sometimes (5–29%) | In 1 condition |
| SLC20A2solute carrier family 20 member 2 | Sometimes (5–29%) | In 1 condition |
| TFR2transferrin receptor 2 | Sometimes (5–29%) | In 2 conditions |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Sometimes (5–29%) | In 1 condition |
| SACSsacsin molecular chaperone | Rarely (1–4%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Not recorded | In 1 condition |
| BMP2bone morphogenetic protein 2 | Not recorded | In 1 condition |
| COQ2coenzyme Q2, polyprenyltransferase | Not recorded | In 1 condition |
| GUCY1A1guanylate cyclase 1 soluble subunit alpha 1 | Not recorded | In 1 condition |
| HEXBhexosaminidase subunit beta | Not recorded | In 1 condition |
| HFEhomeostatic iron regulator | Not recorded | In 1 condition |
| SLC40A1solute carrier family 40 member 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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