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Trait
Slow movements
Clinical name: Bradykinesia
Bradykinesia literally means slow movement, and is used clinically to denote a slowness in the execution of movement (in contrast to hypokinesia, which is used to refer to slowness in the initiation of movement).
Summary
- Also called
- Slowness of movements
- Body system
- Abnormality of the nervous system
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This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/traits/bradykinesia.json"
page <- fromJSON(url)
page$trait$nameSlow movementsHP:0002067
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Get my Genome Test130 genes linked to Slow movements
Changes in these genes cause rare conditions in which Slow movements is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AHDC1AT-hook DNA binding motif containing 1 | Always | In 1 condition |
| ATP13A2ATPase cation transporting 13A2 | Always | In 4 conditions |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Always | In 3 conditions |
| ATP6AP2ATPase H+ transporting accessory protein 2 | Always | In 3 conditions |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Always | In 3 conditions |
| EIF2AK1eukaryotic translation initiation factor 2 alpha kinase 1 | Always | In 1 condition |
| EPG5ectopic P-granules 5 autophagy tethering factor | Always | In 1 condition |
| HTThuntingtin | Always | In 4 conditions |
| LRRC7leucine rich repeat containing 7 | Always | In 1 condition |
| MAPTmicrotubule associated protein tau | Always | In 6 conditions |
| MECP2methyl-CpG binding protein 2 | Always | In 2 conditions |
| MYORGmyogenesis regulating glycosidase | Always | In 3 conditions |
| PARK7Parkinsonism associated deglycase | Always | In 2 conditions |
| PDE8Bphosphodiesterase 8B | Always | In 2 conditions |
| PET117PET117 cytochrome c oxidase chaperone | Always | In 1 condition |
| PLA2G6phospholipase A2 group VI | Always | In 3 conditions |
| POLGDNA polymerase gamma, catalytic subunit | Always | In 4 conditions |
| PRKNparkin RBR E3 ubiquitin protein ligase | Always | In 2 conditions |
| PTRHD1peptidyl-tRNA hydrolase domain containing 1 | Always | In 1 condition |
| RAB32RAB32, member RAS oncogene family | Always | In 1 condition |
| RAB39BRAB39B, member RAS oncogene family | Always | In 1 condition |
| SNCAsynuclein alpha | Always | In 4 conditions |
| SYNJ1synaptojanin 1 | Always | In 3 conditions |
| UQCRC1ubiquinol-cytochrome c reductase core protein 1 | Always | In 1 condition |
| CHCHD2coiled-coil-helix-coiled-coil-helix domain containing 2 | Very often (80–99%) | In 1 condition |
| NIT1nitrilase 1 | Very often (80–99%) | In 1 condition |
| PODXLpodocalyxin like | Very often (80–99%) | In 2 conditions |
| SLC6A3solute carrier family 6 member 3 | Very often (80–99%) | In 2 conditions |
| ACTA1actin alpha 1, skeletal muscle | Often (30–79%) | In 1 condition |
| ATCAYATCAY kinesin light chain interacting caytaxin | Often (30–79%) | In 1 condition |
| ATXN1ataxin 1 | Often (30–79%) | In 1 condition |
| ATXN10ataxin 10 | Often (30–79%) | In 1 condition |
| ATXN8ataxin 8 | Often (30–79%) | In 1 condition |
| ATXN8OSATXN8 opposite strand lncRNA | Often (30–79%) | In 2 conditions |
| CMPK2cytidine/uridine monophosphate kinase 2 | Often (30–79%) | In 1 condition |
| COQ2coenzyme Q2, polyprenyltransferase | Often (30–79%) | In 3 conditions |
| EIF2AK2eukaryotic translation initiation factor 2 alpha kinase 2 | Often (30–79%) | In 1 condition |
| FBXO7F-box protein 7 | Often (30–79%) | In 2 conditions |
| FGF13fibroblast growth factor 13 | Often (30–79%) | In 2 conditions |
| FTLferritin light chain | Often (30–79%) | In 2 conditions |
Show 90 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| GABRA1gamma-aminobutyric acid type A receptor subunit alpha1 | Often (30–79%) | In 1 condition |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Often (30–79%) | In 2 conditions |
| GCH1GTP cyclohydrolase 1 | Often (30–79%) | In 2 conditions |
| JAM2junctional adhesion molecule 2 | Often (30–79%) | In 3 conditions |
| KBTBD13kelch repeat and BTB domain containing 13 | Often (30–79%) | In 1 condition |
| KLHL41kelch like family member 41 | Often (30–79%) | In 1 condition |
| MYPNmyopalladin | Often (30–79%) | In 1 condition |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Often (30–79%) | In 2 conditions |
| NEBnebulin | Often (30–79%) | In 1 condition |
| NR4A2nuclear receptor subfamily 4 group A member 2 | Often (30–79%) | In 3 conditions |
| PCDH19protocadherin 19 | Often (30–79%) | In 1 condition |
| PDGFBplatelet derived growth factor subunit B | Often (30–79%) | In 2 conditions |
| PDGFRBplatelet derived growth factor receptor beta | Often (30–79%) | In 2 conditions |
| POLG2DNA polymerase gamma 2, accessory subunit | Often (30–79%) | In 1 condition |
| PRKAR1Bprotein kinase cAMP-dependent type I regulatory subunit beta | Often (30–79%) | In 1 condition |
| PRKRAprotein activator of interferon induced protein kinase EIF2AK2 | Often (30–79%) | In 2 conditions |
| PRNPprion protein (Kanno blood group) | Often (30–79%) | In 3 conditions |
| PTPAprotein phosphatase 2 phosphatase activator | Often (30–79%) | In 1 condition |
| RAB3ARAB3A, member RAS oncogene family | Often (30–79%) | In 1 condition |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Often (30–79%) | In 1 condition |
| RRP12ribosomal RNA processing 12 homolog | Often (30–79%) | In 2 conditions |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Often (30–79%) | In 2 conditions |
| SCN1Bsodium voltage-gated channel beta subunit 1 | Often (30–79%) | In 2 conditions |
| SCN2Asodium voltage-gated channel alpha subunit 2 | Often (30–79%) | In 2 conditions |
| SCN9Asodium voltage-gated channel alpha subunit 9 | Often (30–79%) | In 2 conditions |
| SLC20A2solute carrier family 20 member 2 | Often (30–79%) | In 2 conditions |
| SLC25A4solute carrier family 25 member 4 | Often (30–79%) | In 1 condition |
| SLC2A3solute carrier family 2 member 3 | Often (30–79%) | In 1 condition |
| SLC30A10solute carrier family 30 member 10 | Often (30–79%) | In 2 conditions |
| SLC39A14solute carrier family 39 member 14 | Often (30–79%) | In 2 conditions |
| SLC9A6solute carrier family 9 member A6 | Often (30–79%) | In 1 condition |
| SPRsepiapterin reductase | Often (30–79%) | In 1 condition |
| TAF1TATA-box binding protein associated factor 1 | Often (30–79%) | In 1 condition |
| THtyrosine hydroxylase | Often (30–79%) | In 1 condition |
| TPM2tropomyosin 2 | Often (30–79%) | In 1 condition |
| TPM3tropomyosin 3 | Often (30–79%) | In 1 condition |
| TSPOAP1TSPO associated protein 1 | Often (30–79%) | In 1 condition |
| TWNKtwinkle mtDNA helicase | Often (30–79%) | In 1 condition |
| WARS2tryptophanyl tRNA synthetase 2, mitochondrial | Often (30–79%) | In 1 condition |
| WDR45WD repeat domain 45 | Often (30–79%) | In 2 conditions |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Often (30–79%) | In 2 conditions |
| ATP5MKATP synthase membrane subunit k | Sometimes (5–29%) | In 1 condition |
| CLTCclathrin heavy chain | Sometimes (5–29%) | In 1 condition |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Sometimes (5–29%) | In 1 condition |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Sometimes (5–29%) | In 2 conditions |
| FARS2phenylalanyl-tRNA synthetase 2, mitochondrial | Sometimes (5–29%) | In 1 condition |
| FMR1fragile X messenger ribonucleoprotein 1 | Sometimes (5–29%) | In 2 conditions |
| GBA1glucosylceramidase beta 1 | Sometimes (5–29%) | In 2 conditions |
| GIGYF2GRB10 interacting GYF protein 2 | Sometimes (5–29%) | In 2 conditions |
| HTRA2HtrA serine peptidase 2 | Sometimes (5–29%) | In 2 conditions |
| IMPDH2inosine monophosphate dehydrogenase 2 | Sometimes (5–29%) | In 1 condition |
| KCNN2potassium calcium-activated channel subfamily N member 2 | Sometimes (5–29%) | In 1 condition |
| LRRK2leucine rich repeat kinase 2 | Sometimes (5–29%) | In 3 conditions |
| PIDD1p53-induced death domain protein 1 | Sometimes (5–29%) | In 1 condition |
| PINK1PTEN induced kinase 1 | Sometimes (5–29%) | In 2 conditions |
| PPP2R2Bprotein phosphatase 2 regulatory subunit Bbeta | Sometimes (5–29%) | In 1 condition |
| PRDX3peroxiredoxin 3 | Sometimes (5–29%) | In 1 condition |
| PTS6-pyruvoyltetrahydropterin synthase | Sometimes (5–29%) | In 2 conditions |
| RRM1ribonucleotide reductase catalytic subunit M1 | Sometimes (5–29%) | In 1 condition |
| TACO1translational activator of cytochrome c oxidase I | Sometimes (5–29%) | In 1 condition |
| TK2thymidine kinase 2 | Sometimes (5–29%) | In 1 condition |
| TOP3ADNA topoisomerase III alpha | Sometimes (5–29%) | In 1 condition |
| TTC19tetratricopeptide repeat domain 19 | Sometimes (5–29%) | In 1 condition |
| UCHL1ubiquitin C-terminal hydrolase L1 | Sometimes (5–29%) | In 2 conditions |
| VPS13Avacuolar protein sorting 13 homolog A | Sometimes (5–29%) | In 1 condition |
| VPS13Cvacuolar protein sorting 13 homolog C | Sometimes (5–29%) | In 1 condition |
| VPS35VPS35 retromer complex component | Sometimes (5–29%) | In 2 conditions |
| ADGRV1adhesion G protein-coupled receptor V1 | Rarely (1–4%) | In 1 condition |
| ATL1atlastin GTPase 1 | Rarely (1–4%) | In 1 condition |
| CPA6carboxypeptidase A6 | Rarely (1–4%) | In 1 condition |
| GABRDgamma-aminobutyric acid type A receptor subunit delta | Rarely (1–4%) | In 1 condition |
| HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1 | Rarely (1–4%) | In 1 condition |
| KCNC3potassium voltage-gated channel subfamily C member 3 | Rarely (1–4%) | In 1 condition |
| PRRT2proline rich transmembrane protein 2 | Rarely (1–4%) | In 1 condition |
| SLC32A1solute carrier family 32 member 1 | Rarely (1–4%) | In 1 condition |
| STX1Bsyntaxin 1B | Rarely (1–4%) | In 1 condition |
| ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide | Not recorded | In 1 condition |
| ATXN2ataxin 2 | Not recorded | In 2 conditions |
| ATXN3ataxin 3 | Not recorded | In 2 conditions |
| COASYCoenzyme A synthase | Not recorded | In 1 condition |
| CSF1Rcolony stimulating factor 1 receptor | Not recorded | In 1 condition |
| DCTN1dynactin subunit 1 | Not recorded | In 1 condition |
| DHDDSdehydrodolichyl diphosphate synthase subunit | Not recorded | In 1 condition |
| DNAJC12DnaJ heat shock protein family (Hsp40) member C12 | Not recorded | In 1 condition |
| EARS2glutamyl-tRNA synthetase 2, mitochondrial | Not recorded | In 1 condition |
| JPH3junctophilin 3 | Not recorded | In 1 condition |
| MT-TTmitochondrially encoded tRNA-Thr (ACN) | Not recorded | In 1 condition |
| PANK2pantothenate kinase 2 | Not recorded | In 1 condition |
| SNCAIPsynuclein alpha interacting protein | Not recorded | In 1 condition |
| TBPTATA-box binding protein | Not recorded | In 2 conditions |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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